Motif ID: Mnx1_Lhx6_Lmx1a

Z-value: 0.730

Transcription factors associated with Mnx1_Lhx6_Lmx1a:

Gene SymbolEntrez IDGene Name
Lhx6 ENSMUSG00000026890.13 Lhx6
Lmx1a ENSMUSG00000026686.8 Lmx1a
Mnx1 ENSMUSG00000001566.8 Mnx1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Lhx6mm10_v2_chr2_-_36104060_361040730.789.7e-04Click!
Lmx1amm10_v2_chr1_+_167689108_1676892390.126.8e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Mnx1_Lhx6_Lmx1a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_62766153 4.524 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr15_-_11037968 4.279 ENSMUST00000058007.5
Rxfp3
relaxin family peptide receptor 3
chr2_+_116067213 3.846 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr6_-_147264124 3.455 ENSMUST00000052296.6
Pthlh
parathyroid hormone-like peptide
chr7_-_45103747 3.427 ENSMUST00000003512.7
Fcgrt
Fc receptor, IgG, alpha chain transporter
chr16_+_43503607 3.250 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chrX_+_169685191 3.163 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr6_+_124304646 2.625 ENSMUST00000112541.2
ENSMUST00000032234.2
Cd163

CD163 antigen

chr18_+_57468478 2.624 ENSMUST00000091892.2
Ctxn3
cortexin 3
chr6_+_125552948 2.605 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr2_-_116067391 2.410 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr2_+_125136692 2.069 ENSMUST00000099452.2
Ctxn2
cortexin 2
chrM_+_2743 2.063 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr6_-_136875794 1.829 ENSMUST00000032342.1
Mgp
matrix Gla protein
chr12_+_38780284 1.696 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr2_+_25372315 1.616 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
Sapcd2


suppressor APC domain containing 2


chr17_-_49564262 1.538 ENSMUST00000057610.6
Daam2
dishevelled associated activator of morphogenesis 2
chr11_+_101582236 1.502 ENSMUST00000039581.7
ENSMUST00000100403.2
ENSMUST00000107194.1
ENSMUST00000128614.1
Tmem106a



transmembrane protein 106A



chr15_-_79285502 1.388 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr16_+_42907563 1.366 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chrM_+_7005 1.348 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr4_-_14621805 1.336 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr11_-_3931960 1.285 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
Tcn2




transcobalamin 2




chr3_+_68869563 1.272 ENSMUST00000054551.2
1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr12_+_38780817 1.251 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr13_-_97747373 1.250 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chrX_-_139871637 1.222 ENSMUST00000033811.7
ENSMUST00000087401.5
Morc4

microrchidia 4

chr3_-_49757257 1.217 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr3_-_116253467 1.196 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr19_-_11604828 1.179 ENSMUST00000025582.4
Ms4a6d
membrane-spanning 4-domains, subfamily A, member 6D
chr4_-_155056784 1.038 ENSMUST00000131173.2
Plch2
phospholipase C, eta 2
chr10_-_115185015 1.003 ENSMUST00000006949.8
Tph2
tryptophan hydroxylase 2
chr3_-_88410295 0.993 ENSMUST00000056370.7
Pmf1
polyamine-modulated factor 1
chr5_+_118169712 0.944 ENSMUST00000054836.6
Hrk
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr15_-_8710734 0.940 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_-_3931789 0.929 ENSMUST00000109992.1
ENSMUST00000109988.1
Tcn2

transcobalamin 2

chr10_-_128744014 0.913 ENSMUST00000026414.7
Dgka
diacylglycerol kinase, alpha
chr19_+_59458372 0.905 ENSMUST00000062216.3
Emx2
empty spiracles homeobox 2
chr11_+_23306884 0.905 ENSMUST00000180046.1
Usp34
ubiquitin specific peptidase 34
chr2_-_60963192 0.891 ENSMUST00000028347.6
Rbms1
RNA binding motif, single stranded interacting protein 1
chr18_+_23415400 0.886 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna

dystrobrevin alpha

chr2_+_22622183 0.879 ENSMUST00000028123.3
Gad2
glutamic acid decarboxylase 2
chr6_+_8948608 0.870 ENSMUST00000160300.1
Nxph1
neurexophilin 1
chrM_+_9452 0.866 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr3_+_54361103 0.843 ENSMUST00000107985.3
ENSMUST00000117373.1
ENSMUST00000073012.6
ENSMUST00000081564.6
Postn



periostin, osteoblast specific factor



chr16_+_45094036 0.829 ENSMUST00000061050.5
Ccdc80
coiled-coil domain containing 80
chr2_+_152754156 0.821 ENSMUST00000010020.5
Cox4i2
cytochrome c oxidase subunit IV isoform 2
chr10_+_26772477 0.821 ENSMUST00000039557.7
Arhgap18
Rho GTPase activating protein 18
chr5_+_13398688 0.811 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr11_+_23306910 0.794 ENSMUST00000137823.1
Usp34
ubiquitin specific peptidase 34
chr9_+_65890237 0.775 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr12_+_38783503 0.762 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr3_-_106790143 0.757 ENSMUST00000038845.8
Cd53
CD53 antigen
chr4_-_154636831 0.744 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr2_+_109917639 0.711 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr19_-_15924560 0.696 ENSMUST00000162053.1
Psat1
phosphoserine aminotransferase 1
chr6_+_7555053 0.683 ENSMUST00000090679.2
ENSMUST00000184986.1
Tac1

tachykinin 1

chr13_-_97747399 0.677 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr3_-_116712644 0.676 ENSMUST00000029569.2
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr3_+_122419772 0.675 ENSMUST00000029766.4
Bcar3
breast cancer anti-estrogen resistance 3
chr3_-_66296807 0.664 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chr15_-_8710409 0.648 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr12_-_40037387 0.627 ENSMUST00000146905.1
Arl4a
ADP-ribosylation factor-like 4A
chr16_+_43235856 0.626 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr4_+_136143497 0.618 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr2_-_164171113 0.609 ENSMUST00000045196.3
Kcns1
K+ voltage-gated channel, subfamily S, 1
chr6_+_138140521 0.609 ENSMUST00000120939.1
ENSMUST00000120302.1
Mgst1

microsomal glutathione S-transferase 1

chr19_-_15924928 0.608 ENSMUST00000025542.3
Psat1
phosphoserine aminotransferase 1
chr3_+_62419668 0.592 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr9_-_77347889 0.579 ENSMUST00000185039.1
Mlip
muscular LMNA-interacting protein
chr1_-_152625212 0.576 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr10_-_8886033 0.571 ENSMUST00000015449.5
Sash1
SAM and SH3 domain containing 1
chr14_-_48665098 0.567 ENSMUST00000118578.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr9_-_77347816 0.555 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
Mlip



muscular LMNA-interacting protein



chr18_+_12741324 0.546 ENSMUST00000115857.2
ENSMUST00000121018.1
ENSMUST00000119108.1
Cabyr


calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)


chr7_-_37773555 0.535 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr1_+_19103022 0.529 ENSMUST00000037294.7
Tfap2d
transcription factor AP-2, delta
chrM_+_11734 0.521 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr6_+_145934113 0.520 ENSMUST00000032383.7
Sspn
sarcospan
chr12_+_38781093 0.515 ENSMUST00000161513.1
Etv1
ets variant gene 1
chrM_+_10167 0.514 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr17_-_36032682 0.513 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr8_-_84662841 0.505 ENSMUST00000060427.4
Ier2
immediate early response 2
chrX_+_166344692 0.497 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr11_+_116657106 0.488 ENSMUST00000116318.2
Gm11744
predicted gene 11744
chrX_+_56779437 0.488 ENSMUST00000114773.3
Fhl1
four and a half LIM domains 1
chr5_-_77115145 0.484 ENSMUST00000081964.5
Hopx
HOP homeobox
chr1_-_55226768 0.483 ENSMUST00000027121.8
ENSMUST00000114428.2
Rftn2

raftlin family member 2

chrX_-_134111852 0.475 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr4_+_154964117 0.466 ENSMUST00000030931.4
ENSMUST00000070953.4
Pank4

pantothenate kinase 4

chr5_+_64812336 0.451 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr16_+_43363855 0.449 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr18_-_15063560 0.448 ENSMUST00000168989.1
Kctd1
potassium channel tetramerisation domain containing 1
chr2_+_36230426 0.447 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr3_-_33082004 0.445 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chrX_-_155216338 0.443 ENSMUST00000112551.3
Sat1
spermidine/spermine N1-acetyl transferase 1
chr17_-_24073479 0.437 ENSMUST00000017090.5
Kctd5
potassium channel tetramerisation domain containing 5
chr4_-_45532470 0.426 ENSMUST00000147448.1
Shb
src homology 2 domain-containing transforming protein B
chr5_-_137684665 0.417 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
Agfg2


ArfGAP with FG repeats 2


chr1_-_9299238 0.414 ENSMUST00000140295.1
Sntg1
syntrophin, gamma 1
chr6_+_138140298 0.408 ENSMUST00000008684.4
Mgst1
microsomal glutathione S-transferase 1
chr14_+_25980039 0.404 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chr13_-_78196373 0.391 ENSMUST00000125176.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chrM_-_14060 0.383 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr10_-_53647080 0.383 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chr7_-_46667375 0.380 ENSMUST00000107669.2
Tph1
tryptophan hydroxylase 1
chr14_+_79515618 0.374 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr1_-_163725123 0.372 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr9_+_96258697 0.371 ENSMUST00000179416.1
Tfdp2
transcription factor Dp 2
chrX_+_103356464 0.367 ENSMUST00000116547.2
Chic1
cysteine-rich hydrophobic domain 1
chrM_+_7759 0.364 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr7_+_103550368 0.355 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr19_-_50678642 0.347 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr12_-_111813834 0.339 ENSMUST00000021715.5
Xrcc3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr16_+_43364145 0.338 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr12_+_74297474 0.337 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr8_+_121116163 0.322 ENSMUST00000054691.6
Foxc2
forkhead box C2
chr1_+_171840607 0.316 ENSMUST00000136479.1
ENSMUST00000042302.6
Cd84

CD84 antigen

chr3_-_89349968 0.315 ENSMUST00000074582.6
ENSMUST00000107448.2
ENSMUST00000029676.5
Adam15


a disintegrin and metallopeptidase domain 15 (metargidin)


chr7_-_100656953 0.313 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
Plekhb1


pleckstrin homology domain containing, family B (evectins) member 1


chr1_+_63176818 0.312 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr1_-_56969864 0.295 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr2_-_177267036 0.289 ENSMUST00000108963.1
Gm14409
predicted gene 14409
chr9_+_72806874 0.288 ENSMUST00000055535.8
Prtg
protogenin homolog (Gallus gallus)
chr1_-_72284248 0.283 ENSMUST00000097698.4
ENSMUST00000027381.6
Pecr

peroxisomal trans-2-enoyl-CoA reductase

chrX_-_75416533 0.282 ENSMUST00000033542.4
Mtcp1
mature T cell proliferation 1
chr6_+_29859374 0.279 ENSMUST00000115238.3
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr13_-_83729544 0.279 ENSMUST00000181705.1
Gm26803
predicted gene, 26803
chr3_+_18054258 0.275 ENSMUST00000026120.6
Bhlhe22
basic helix-loop-helix family, member e22
chr8_-_26119125 0.271 ENSMUST00000037182.7
Hook3
hook homolog 3 (Drosophila)
chr3_+_32436151 0.271 ENSMUST00000029201.7
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr2_-_147186389 0.267 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2

NK2 homeobox 2

chr3_+_133338936 0.267 ENSMUST00000150386.1
ENSMUST00000125858.1
Ppa2

pyrophosphatase (inorganic) 2

chr1_-_158356258 0.264 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chrM_+_14138 0.260 ENSMUST00000082421.1
mt-Cytb
mitochondrially encoded cytochrome b
chr3_-_89349939 0.251 ENSMUST00000107446.1
Adam15
a disintegrin and metallopeptidase domain 15 (metargidin)
chr15_+_18818895 0.247 ENSMUST00000166873.2
Cdh10
cadherin 10
chr17_-_67950908 0.244 ENSMUST00000164647.1
Arhgap28
Rho GTPase activating protein 28
chr2_-_33086366 0.243 ENSMUST00000049618.2
Garnl3
GTPase activating RANGAP domain-like 3
chr6_-_118479237 0.241 ENSMUST00000161170.1
Zfp9
zinc finger protein 9
chr11_-_120549695 0.240 ENSMUST00000034913.4
Fam195b
family with sequence similarity 195, member B
chr4_-_14621494 0.238 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr9_+_62858085 0.237 ENSMUST00000034777.6
ENSMUST00000163820.1
Calml4

calmodulin-like 4

chr11_-_87108656 0.230 ENSMUST00000051395.8
Prr11
proline rich 11
chr14_-_48662740 0.229 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chrX_+_99975570 0.225 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chrX_+_134308084 0.222 ENSMUST00000081064.5
ENSMUST00000101251.1
ENSMUST00000129782.1
Cenpi


centromere protein I


chr6_+_29859662 0.219 ENSMUST00000128927.2
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chrX_+_9885622 0.219 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr6_+_34746368 0.218 ENSMUST00000142716.1
Cald1
caldesmon 1
chr19_+_55895508 0.218 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr7_-_116198487 0.217 ENSMUST00000181981.1
Plekha7
pleckstrin homology domain containing, family A member 7
chr9_+_89199319 0.216 ENSMUST00000138109.1
Mthfs
5, 10-methenyltetrahydrofolate synthetase
chr8_+_83666827 0.215 ENSMUST00000019608.5
Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr18_+_54990280 0.212 ENSMUST00000181538.1
Gm4221
predicted gene 4221
chrX_+_114474312 0.211 ENSMUST00000113371.1
ENSMUST00000040504.5
Klhl4

kelch-like 4

chr1_+_82233112 0.209 ENSMUST00000023262.5
Gm9747
predicted gene 9747
chrX_+_152001845 0.205 ENSMUST00000026289.3
ENSMUST00000112617.3
Hsd17b10

hydroxysteroid (17-beta) dehydrogenase 10

chr12_+_51348019 0.199 ENSMUST00000054308.6
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr18_-_54990124 0.195 ENSMUST00000064763.5
Zfp608
zinc finger protein 608
chr7_+_28881656 0.191 ENSMUST00000066880.4
Capn12
calpain 12
chr6_+_29859686 0.191 ENSMUST00000134438.1
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr12_+_111814170 0.190 ENSMUST00000021714.7
Zfyve21
zinc finger, FYVE domain containing 21
chr3_-_157925056 0.189 ENSMUST00000118539.1
Cth
cystathionase (cystathionine gamma-lyase)
chr18_-_44662251 0.189 ENSMUST00000164666.1
Mcc
mutated in colorectal cancers
chr14_+_55560010 0.181 ENSMUST00000147981.1
ENSMUST00000133256.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr8_-_61902669 0.175 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr18_+_9707639 0.169 ENSMUST00000040069.8
Colec12
collectin sub-family member 12
chr4_-_110292719 0.166 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr18_+_55057557 0.165 ENSMUST00000181765.1
Gm4221
predicted gene 4221
chr10_-_25200110 0.164 ENSMUST00000100012.2
Akap7
A kinase (PRKA) anchor protein 7
chr8_-_67818284 0.164 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr8_+_4238815 0.159 ENSMUST00000003027.7
ENSMUST00000110999.1
Map2k7

mitogen-activated protein kinase kinase 7

chr3_-_79841729 0.156 ENSMUST00000168038.1
Tmem144
transmembrane protein 144
chr12_-_73047179 0.150 ENSMUST00000050029.7
Six1
sine oculis-related homeobox 1
chr14_+_55559993 0.149 ENSMUST00000117236.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr15_-_50889691 0.149 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr18_-_6516089 0.148 ENSMUST00000115870.2
Epc1
enhancer of polycomb homolog 1 (Drosophila)
chr7_+_25681158 0.147 ENSMUST00000108403.3
B9d2
B9 protein domain 2
chr10_-_37138863 0.147 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr12_-_75735729 0.147 ENSMUST00000021450.4
Sgpp1
sphingosine-1-phosphate phosphatase 1
chr3_+_24333046 0.143 ENSMUST00000077389.6
Gm7536
predicted gene 7536
chr18_+_37518341 0.142 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr14_+_54894133 0.134 ENSMUST00000116476.2
ENSMUST00000022808.7
ENSMUST00000150975.1
Pabpn1


poly(A) binding protein, nuclear 1


chr10_+_88146992 0.131 ENSMUST00000052355.7
Nup37
nucleoporin 37
chr5_+_19907502 0.130 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr6_+_29853746 0.125 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
Ahcyl2



S-adenosylhomocysteine hydrolase-like 2



chr4_+_12906838 0.124 ENSMUST00000143186.1
ENSMUST00000183345.1
Triqk

triple QxxK/R motif containing

chr1_-_24612700 0.118 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr19_+_44493472 0.117 ENSMUST00000041163.4
Wnt8b
wingless related MMTV integration site 8b
chr3_+_40800778 0.117 ENSMUST00000169566.1
Plk4
polo-like kinase 4
chr3_-_146495115 0.116 ENSMUST00000093951.2
Spata1
spermatogenesis associated 1
chr1_-_180330550 0.114 ENSMUST00000050581.3
Gm5069
predicted pseudogene 5069
chr10_-_39122277 0.110 ENSMUST00000136546.1
Fam229b
family with sequence similarity 229, member B
chr3_+_32436376 0.109 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chrX_-_157415286 0.107 ENSMUST00000079945.4
ENSMUST00000138396.1
Phex

phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)

chr14_+_54894573 0.105 ENSMUST00000141446.1
ENSMUST00000139985.1
ENSMUST00000172557.1
Pabpn1


poly(A) binding protein, nuclear 1


chr7_-_30559600 0.104 ENSMUST00000043975.4
ENSMUST00000156241.1
Lin37

lin-37 homolog (C. elegans)

chr1_-_75046639 0.102 ENSMUST00000152855.1
Nhej1
nonhomologous end-joining factor 1
chrM_+_9870 0.101 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0015889 cobalamin transport(GO:0015889)
0.6 3.5 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.4 1.6 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.3 4.1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.3 1.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.3 1.0 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.2 0.7 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.2 0.9 GO:0006538 glutamate catabolic process(GO:0006538)
0.2 0.8 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.2 1.4 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.2 0.6 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.2 0.9 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.2 0.5 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.2 6.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 0.5 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.2 0.8 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000343)
0.2 0.8 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.1 1.0 GO:0019532 oxalate transport(GO:0019532)
0.1 0.4 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.1 0.4 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 2.6 GO:0006953 acute-phase response(GO:0006953)
0.1 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.7 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 0.4 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.5 GO:0072592 regulation of integrin biosynthetic process(GO:0045113) oxygen metabolic process(GO:0072592)
0.1 3.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 2.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.1 0.3 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278) regulation of vascular wound healing(GO:0061043) glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144)
0.1 0.7 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 0.3 GO:2001180 regulation of interleukin-18 production(GO:0032661) negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.5 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.7 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.3 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 1.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707) resolution of recombination intermediates(GO:0071139)
0.1 0.5 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1 0.2 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.2 GO:0072106 regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107)
0.1 0.5 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.8 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.3 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 1.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.8 GO:0019985 translesion synthesis(GO:0019985)
0.1 0.4 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.2 GO:1905065 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) regulation of vascular smooth muscle cell differentiation(GO:1905063) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.1 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.4 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 1.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.6 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.1 2.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 0.3 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 2.8 GO:0022900 electron transport chain(GO:0022900)
0.1 1.1 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.1 0.9 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.5 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 3.2 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0002237 response to molecule of bacterial origin(GO:0002237) response to lipopolysaccharide(GO:0032496)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.6 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.9 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 1.6 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.1 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.6 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.0 0.9 GO:0019228 neuronal action potential(GO:0019228)
0.0 2.5 GO:0001889 liver development(GO:0001889)
0.0 0.6 GO:0071398 cellular response to fatty acid(GO:0071398)
0.0 0.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.2 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.2 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.2 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.3 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.5 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.1 GO:0051096 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.0 0.0 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.0 0.1 GO:0090148 membrane fission(GO:0090148)
0.0 0.4 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.1 GO:0036233 glycine import(GO:0036233)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 1.0 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 1.7 GO:0000124 SAGA complex(GO:0000124)
0.1 1.4 GO:0071439 clathrin complex(GO:0071439)
0.1 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.5 GO:0071438 NADPH oxidase complex(GO:0043020) invadopodium membrane(GO:0071438)
0.1 0.4 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.6 GO:0043205 fibril(GO:0043205)
0.1 6.1 GO:0070469 respiratory chain(GO:0070469)
0.1 1.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.9 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 1.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.8 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.4 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0019770 IgG receptor activity(GO:0019770)
0.5 1.4 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.4 2.6 GO:0019865 immunoglobulin binding(GO:0019865)
0.3 1.6 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.3 2.2 GO:0031419 cobalamin binding(GO:0031419)
0.2 3.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 0.5 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.4 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 4.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 2.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.9 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.7 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 1.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 2.2 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.3 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 4.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 4.3 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.1 0.7 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.5 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 1.3 GO:0008483 transaminase activity(GO:0008483)
0.1 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 1.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.2 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.1 0.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 1.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.8 GO:0001968 fibronectin binding(GO:0001968)
0.0 5.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.7 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 1.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.0 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 5.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.4 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)