Motif ID: Msx2_Hoxd4

Z-value: 1.882

Transcription factors associated with Msx2_Hoxd4:

Gene SymbolEntrez IDGene Name
Msx2 ENSMUSG00000021469.8 Msx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Msx2mm10_v2_chr13_-_53473074_534730740.078.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Msx2_Hoxd4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_190170671 11.941 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr5_-_62766153 9.929 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_-_190170178 9.175 ENSMUST00000177288.1
Prox1
prospero-related homeobox 1
chr12_+_38783503 7.210 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr15_-_79285502 6.924 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr10_-_33624587 6.456 ENSMUST00000160299.1
ENSMUST00000019920.6
Clvs2

clavesin 2

chr1_-_163725123 5.011 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr14_-_88471396 4.932 ENSMUST00000061628.5
Pcdh20
protocadherin 20
chr2_+_125136692 4.132 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr3_+_68869563 3.947 ENSMUST00000054551.2
1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr6_-_36811361 3.814 ENSMUST00000101534.1
Ptn
pleiotrophin
chr14_+_115042752 3.484 ENSMUST00000134140.2
Mir17hg
Mir17 host gene 1 (non-protein coding)
chr9_+_22454290 3.015 ENSMUST00000168332.1
Gm17545
predicted gene, 17545
chr6_+_124304646 2.986 ENSMUST00000112541.2
ENSMUST00000032234.2
Cd163

CD163 antigen

chr2_+_4017727 2.744 ENSMUST00000177457.1
Frmd4a
FERM domain containing 4A
chr3_+_52268337 2.705 ENSMUST00000053764.5
Foxo1
forkhead box O1
chrM_+_7759 2.618 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr18_+_52767994 2.598 ENSMUST00000025413.7
ENSMUST00000163742.2
ENSMUST00000178011.1
Sncaip


synuclein, alpha interacting protein (synphilin)


chr13_+_75967704 2.437 ENSMUST00000022081.1
Spata9
spermatogenesis associated 9
chr7_-_101845300 2.405 ENSMUST00000094141.5
Folr2
folate receptor 2 (fetal)
chr1_+_165788681 2.306 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
Cd247



CD247 antigen



chr4_+_136143497 2.278 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chrX_+_56454871 2.223 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr12_+_36314160 2.198 ENSMUST00000041407.5
Sostdc1
sclerostin domain containing 1
chr10_+_75037066 2.185 ENSMUST00000147802.1
ENSMUST00000020391.5
Rab36

RAB36, member RAS oncogene family

chr2_+_109280738 2.180 ENSMUST00000028527.7
Kif18a
kinesin family member 18A
chr3_+_62419668 2.131 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr1_+_165788746 2.023 ENSMUST00000161559.2
Cd247
CD247 antigen
chr1_-_152625212 2.008 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr3_+_84952146 1.866 ENSMUST00000029727.7
Fbxw7
F-box and WD-40 domain protein 7
chr6_-_124779686 1.806 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
Lrrc23



leucine rich repeat containing 23



chr3_-_49757257 1.778 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr12_+_74297474 1.767 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr9_-_114390633 1.673 ENSMUST00000084881.4
Crtap
cartilage associated protein
chr16_-_44016387 1.656 ENSMUST00000036174.3
Gramd1c
GRAM domain containing 1C
chr18_+_59062462 1.531 ENSMUST00000058633.2
ENSMUST00000175897.1
ENSMUST00000118510.1
ENSMUST00000175830.1
A730017C20Rik



RIKEN cDNA A730017C20 gene



chr17_-_90088343 1.505 ENSMUST00000173917.1
Nrxn1
neurexin I
chr7_-_45920830 1.497 ENSMUST00000164119.1
Emp3
epithelial membrane protein 3
chr4_+_124657646 1.477 ENSMUST00000053491.7
Pou3f1
POU domain, class 3, transcription factor 1
chr2_-_63184253 1.438 ENSMUST00000075052.3
ENSMUST00000112454.1
Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr3_+_40800778 1.296 ENSMUST00000169566.1
Plk4
polo-like kinase 4
chr2_-_33086366 1.287 ENSMUST00000049618.2
Garnl3
GTPase activating RANGAP domain-like 3
chr3_-_85741389 1.277 ENSMUST00000094148.4
Fam160a1
family with sequence similarity 160, member A1
chr7_-_45921418 1.262 ENSMUST00000038876.5
Emp3
epithelial membrane protein 3
chr17_-_25785324 1.260 ENSMUST00000150324.1
Haghl
hydroxyacylglutathione hydrolase-like
chr2_-_60125651 1.260 ENSMUST00000112550.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr2_-_144527341 1.249 ENSMUST00000163701.1
ENSMUST00000081982.5
Dzank1

double zinc ribbon and ankyrin repeat domains 1

chrM_+_2743 1.194 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr5_-_62765618 1.167 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_-_129121889 1.167 ENSMUST00000139450.1
ENSMUST00000125931.1
ENSMUST00000116444.2
Hpca


hippocalcin


chr7_-_84679346 1.152 ENSMUST00000069537.2
ENSMUST00000178385.1
Zfand6

zinc finger, AN1-type domain 6

chr11_+_103133333 1.114 ENSMUST00000124928.1
ENSMUST00000062530.4
Hexim2

hexamethylene bis-acetamide inducible 2

chr5_-_107875035 1.111 ENSMUST00000138111.1
ENSMUST00000112642.1
Evi5

ecotropic viral integration site 5

chr5_+_48242549 1.069 ENSMUST00000172493.1
Slit2
slit homolog 2 (Drosophila)
chr3_-_150073620 1.015 ENSMUST00000057740.5
Rpsa-ps10
ribosomal protein SA, pseudogene 10
chrM_+_9452 1.014 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr3_-_116253467 1.014 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chrM_-_14060 1.004 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr13_+_23555023 1.002 ENSMUST00000045301.6
Hist1h1d
histone cluster 1, H1d
chr1_-_132390301 0.984 ENSMUST00000132435.1
Tmcc2
transmembrane and coiled-coil domains 2
chrX_-_94123359 0.982 ENSMUST00000137853.1
ENSMUST00000088102.5
ENSMUST00000113927.1
Zfx


zinc finger protein X-linked


chr4_-_40722307 0.982 ENSMUST00000181475.1
Gm6297
predicted gene 6297
chr3_-_36571952 0.963 ENSMUST00000029270.3
Ccna2
cyclin A2
chr17_-_46327949 0.938 ENSMUST00000047970.7
Abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr13_+_51408618 0.937 ENSMUST00000087978.3
S1pr3
sphingosine-1-phosphate receptor 3
chr11_+_103133303 0.936 ENSMUST00000107037.1
Hexim2
hexamethylene bis-acetamide inducible 2
chr17_-_14694223 0.913 ENSMUST00000170872.1
Thbs2
thrombospondin 2
chr2_+_155751117 0.886 ENSMUST00000029140.5
ENSMUST00000132608.1
Procr

protein C receptor, endothelial

chr3_-_146495115 0.864 ENSMUST00000093951.2
Spata1
spermatogenesis associated 1
chr2_+_76650264 0.853 ENSMUST00000099986.2
Dfnb59
deafness, autosomal recessive 59 (human)
chr1_-_24612700 0.828 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr3_+_19957037 0.786 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chr3_-_66296807 0.784 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chr17_+_45506825 0.770 ENSMUST00000024733.7
Aars2
alanyl-tRNA synthetase 2, mitochondrial (putative)
chr2_+_132847719 0.768 ENSMUST00000124836.1
ENSMUST00000154160.1
Crls1

cardiolipin synthase 1

chr6_+_29853746 0.749 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
Ahcyl2



S-adenosylhomocysteine hydrolase-like 2



chr13_-_95250166 0.720 ENSMUST00000162153.1
ENSMUST00000160957.2
ENSMUST00000159598.1
ENSMUST00000162412.1
Pde8b



phosphodiesterase 8B



chr11_-_109472611 0.709 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr13_+_49544443 0.706 ENSMUST00000177948.1
ENSMUST00000021820.6
Aspn

asporin

chr7_+_144838590 0.698 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr4_+_3940747 0.676 ENSMUST00000119403.1
Chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr16_+_14705832 0.675 ENSMUST00000023356.6
Snai2
snail homolog 2 (Drosophila)
chr6_+_34746368 0.643 ENSMUST00000142716.1
Cald1
caldesmon 1
chr10_+_128303322 0.632 ENSMUST00000005825.6
Pan2
PAN2 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr18_+_37320374 0.604 ENSMUST00000078271.2
Pcdhb5
protocadherin beta 5
chr18_+_37518341 0.592 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chrM_+_10167 0.590 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr9_-_89705017 0.567 ENSMUST00000058488.6
Tmed3
transmembrane emp24 domain containing 3
chr15_+_85510812 0.561 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr1_-_163289214 0.544 ENSMUST00000183691.1
Prrx1
paired related homeobox 1
chr7_-_121074501 0.544 ENSMUST00000047194.2
Igsf6
immunoglobulin superfamily, member 6
chr2_-_73453918 0.535 ENSMUST00000102679.1
Wipf1
WAS/WASL interacting protein family, member 1
chr15_+_21111452 0.525 ENSMUST00000075132.6
Cdh12
cadherin 12
chr17_-_24073479 0.509 ENSMUST00000017090.5
Kctd5
potassium channel tetramerisation domain containing 5
chr1_-_133921393 0.489 ENSMUST00000048432.5
Prelp
proline arginine-rich end leucine-rich repeat
chr1_+_63176818 0.484 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chrM_+_9870 0.460 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr1_-_133661318 0.451 ENSMUST00000027736.6
ENSMUST00000179598.1
Zc3h11a
Zbed6
zinc finger CCCH type containing 11A
zinc finger, BED domain containing 6
chr1_-_186749304 0.448 ENSMUST00000001339.5
Rrp15
ribosomal RNA processing 15 homolog (S. cerevisiae)
chr10_-_13324160 0.446 ENSMUST00000105545.4
Phactr2
phosphatase and actin regulator 2
chr4_-_148159838 0.441 ENSMUST00000151127.1
ENSMUST00000105705.2
Fbxo44

F-box protein 44

chr10_+_5593718 0.434 ENSMUST00000051809.8
Myct1
myc target 1
chr4_-_149126688 0.429 ENSMUST00000030815.2
Cort
cortistatin
chr4_-_141078302 0.414 ENSMUST00000030760.8
Necap2
NECAP endocytosis associated 2
chr11_+_95010277 0.380 ENSMUST00000124735.1
Samd14
sterile alpha motif domain containing 14
chr9_-_112187766 0.377 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr12_-_85374696 0.365 ENSMUST00000040766.7
Tmed10
transmembrane emp24-like trafficking protein 10 (yeast)
chr7_+_126950837 0.362 ENSMUST00000106332.1
Sez6l2
seizure related 6 homolog like 2
chr3_+_144570409 0.350 ENSMUST00000082437.3
Sep15
selenoprotein
chr8_-_70527645 0.345 ENSMUST00000132867.1
Kxd1
KxDL motif containing 1
chr14_+_54259227 0.339 ENSMUST00000041197.7
Abhd4
abhydrolase domain containing 4
chr5_-_31180110 0.326 ENSMUST00000043161.6
ENSMUST00000088010.5
Gtf3c2

general transcription factor IIIC, polypeptide 2, beta

chr1_+_180109192 0.308 ENSMUST00000143176.1
ENSMUST00000135056.1
Cdc42bpa

CDC42 binding protein kinase alpha

chr15_-_50890396 0.278 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr2_+_72054598 0.258 ENSMUST00000028525.5
Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr5_-_31179901 0.254 ENSMUST00000101411.2
ENSMUST00000140793.1
Gtf3c2

general transcription factor IIIC, polypeptide 2, beta

chr10_-_14718191 0.253 ENSMUST00000020016.4
Gje1
gap junction protein, epsilon 1
chr12_-_76177251 0.250 ENSMUST00000101291.3
ENSMUST00000076634.4
Esr2

estrogen receptor 2 (beta)

chrM_+_8600 0.244 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr4_-_148160031 0.210 ENSMUST00000057907.3
Fbxo44
F-box protein 44
chr19_-_53371766 0.201 ENSMUST00000086887.1
Gm10197
predicted gene 10197
chr5_-_146220901 0.188 ENSMUST00000169407.2
ENSMUST00000161331.1
ENSMUST00000159074.2
ENSMUST00000067837.3
Rnf6



ring finger protein (C3H2C3 type) 6



chr3_+_144570687 0.175 ENSMUST00000106211.1
Sep15
selenoprotein
chr7_+_123123870 0.173 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chrX_-_150814265 0.171 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
Maged2


melanoma antigen, family D, 2


chr9_-_107770945 0.170 ENSMUST00000183248.1
ENSMUST00000182022.1
ENSMUST00000035199.6
ENSMUST00000182659.1
Rbm5



RNA binding motif protein 5



chr18_-_43477764 0.167 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chrX_-_8132770 0.166 ENSMUST00000130832.1
ENSMUST00000033506.6
ENSMUST00000115623.1
ENSMUST00000153839.1
Wdr13



WD repeat domain 13



chr8_+_70527724 0.163 ENSMUST00000119353.2
ENSMUST00000075491.7
Fkbp8

FK506 binding protein 8

chr1_-_72284248 0.154 ENSMUST00000097698.4
ENSMUST00000027381.6
Pecr

peroxisomal trans-2-enoyl-CoA reductase

chr12_-_108179237 0.151 ENSMUST00000071095.7
Setd3
SET domain containing 3
chr7_-_34654342 0.149 ENSMUST00000108069.1
Kctd15
potassium channel tetramerisation domain containing 15
chr3_-_144570136 0.145 ENSMUST00000043325.7
Hs2st1
heparan sulfate 2-O-sulfotransferase 1
chr17_+_46161021 0.132 ENSMUST00000024748.7
ENSMUST00000172170.1
Gtpbp2

GTP binding protein 2

chr11_+_78465697 0.119 ENSMUST00000001126.3
Slc46a1
solute carrier family 46, member 1
chr2_-_176144697 0.113 ENSMUST00000178872.1
Gm2004
predicted gene 2004
chr12_+_108179738 0.108 ENSMUST00000101055.4
Ccnk
cyclin K
chr4_-_62519885 0.105 ENSMUST00000107444.1
ENSMUST00000030090.3
Alad

aminolevulinate, delta-, dehydratase

chr10_+_14523062 0.095 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr11_-_74724670 0.091 ENSMUST00000021091.8
Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr6_+_34745952 0.087 ENSMUST00000123823.1
ENSMUST00000136907.1
ENSMUST00000126181.1
Cald1


caldesmon 1


chr7_+_65693417 0.073 ENSMUST00000032726.7
ENSMUST00000107495.3
Tm2d3

TM2 domain containing 3

chr7_-_73541738 0.071 ENSMUST00000169922.2
Chd2
chromodomain helicase DNA binding protein 2
chr9_+_78051938 0.068 ENSMUST00000024104.7
Gcm1
glial cells missing homolog 1 (Drosophila)
chr12_+_52516077 0.064 ENSMUST00000110725.1
Arhgap5
Rho GTPase activating protein 5
chr3_-_154330543 0.061 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr7_+_97400003 0.051 ENSMUST00000032882.8
Ndufc2
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2
chr5_-_72168142 0.043 ENSMUST00000013693.6
Commd8
COMM domain containing 8
chr6_-_136941887 0.037 ENSMUST00000111891.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr9_+_30942541 0.031 ENSMUST00000068135.6
Adamts8
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
chr2_+_180710117 0.024 ENSMUST00000029090.2
Gid8
GID complex subunit 8 homolog (S. cerevisiae)
chrX_-_103981242 0.023 ENSMUST00000121153.1
ENSMUST00000070705.4
Rlim

ring finger protein, LIM domain interacting

chr1_+_137928100 0.023 ENSMUST00000054333.2
A130050O07Rik
RIKEN cDNA A130050O07 gene
chr9_-_55919605 0.023 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr3_+_106113229 0.015 ENSMUST00000079132.5
ENSMUST00000139086.1
Chia

chitinase, acidic


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 21.1 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
1.3 3.8 GO:1904395 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.5 6.8 GO:0051764 actin crosslink formation(GO:0051764)
0.5 1.9 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.4 1.2 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.4 2.2 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.4 1.1 GO:0050929 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.3 2.7 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.3 1.5 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.3 2.4 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.3 1.3 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.3 0.8 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.2 0.7 GO:0035106 operant conditioning(GO:0035106)
0.2 0.7 GO:0030916 otic vesicle formation(GO:0030916)
0.2 0.7 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.2 5.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.2 1.7 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.2 3.0 GO:0006953 acute-phase response(GO:0006953)
0.2 2.8 GO:0032060 bleb assembly(GO:0032060)
0.1 5.0 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.1 1.0 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.7 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 2.2 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 0.4 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.1 0.9 GO:1901550 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.1 0.8 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 2.1 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 1.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.7 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 2.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 1.3 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 6.5 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 0.3 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.1 2.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662) cellular response to fatty acid(GO:0071398)
0.1 0.2 GO:0060743 estrous cycle(GO:0044849) epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 2.6 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 5.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.5 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 1.0 GO:0060746 parental behavior(GO:0060746)
0.1 2.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.8 GO:0046688 response to copper ion(GO:0046688)
0.1 1.5 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.5 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 1.2 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.6 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.0 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 1.0 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.7 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.4 GO:0045187 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.1 GO:0072344 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.9 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.5 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 0.5 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.5 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 1.0 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.4 GO:0007097 nuclear migration(GO:0007097)
0.0 1.1 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.4 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.7 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 1.1 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 1.0 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.2 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.2 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.1 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.4 GO:0034605 cellular response to heat(GO:0034605)
0.0 1.2 GO:0098780 mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.7 6.9 GO:0071439 clathrin complex(GO:0071439)
0.5 1.9 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.3 2.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.2 2.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 2.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 0.6 GO:0031251 PAN complex(GO:0031251)
0.2 1.3 GO:0098536 deuterosome(GO:0098536)
0.1 1.0 GO:0001940 male pronucleus(GO:0001940)
0.1 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 1.2 GO:0044327 dendritic spine head(GO:0044327)
0.1 0.9 GO:0031091 platelet alpha granule(GO:0031091)
0.1 0.7 GO:0030478 actin cap(GO:0030478)
0.1 0.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 6.9 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 4.3 GO:0070469 respiratory chain(GO:0070469)
0.1 0.3 GO:0044316 cone cell pedicle(GO:0044316)
0.0 3.8 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.9 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.1 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.0 0.5 GO:0000346 transcription export complex(GO:0000346)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 2.4 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 3.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 21.1 GO:0050693 LBD domain binding(GO:0050693)
1.3 3.8 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.8 2.4 GO:0051870 methotrexate binding(GO:0051870)
0.4 1.9 GO:0050816 phosphothreonine binding(GO:0050816)
0.3 2.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3 2.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.3 10.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.3 6.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.3 0.8 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.2 0.2 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.2 6.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 2.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 0.8 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 2.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 0.8 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.2 1.1 GO:0043237 laminin-1 binding(GO:0043237)
0.1 3.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 4.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.9 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.7 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 2.3 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.2 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.5 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.8 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 3.0 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 4.7 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 2.7 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 5.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.9 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)