Motif ID: Msx3

Z-value: 0.474


Transcription factors associated with Msx3:

Gene SymbolEntrez IDGene Name
Msx3 ENSMUSG00000025469.9 Msx3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Msx3mm10_v2_chr7_-_140049140_140049180-0.293.2e-01Click!


Activity profile for motif Msx3.

activity profile for motif Msx3


Sorted Z-values histogram for motif Msx3

Sorted Z-values for motif Msx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Msx3

PNG image of the network

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Top targets:


Showing 1 to 20 of 62 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_72441852 0.640 ENSMUST00000162159.1
 Lrrc9
leucine rich repeat containing 9
chr12_+_72441933 0.613 ENSMUST00000161284.1
 Lrrc9
leucine rich repeat containing 9
chr17_+_21383725 0.555 ENSMUST00000056107.4
ENSMUST00000162659.1
 Zfp677

zinc finger protein 677

chr2_-_45117349 0.494 ENSMUST00000176438.2
 Zeb2
zinc finger E-box binding homeobox 2
chr13_-_29984219 0.469 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3
chr4_-_14621494 0.393 ENSMUST00000149633.1
 Slc26a7
solute carrier family 26, member 7
chr4_-_14621669 0.380 ENSMUST00000143105.1
 Slc26a7
solute carrier family 26, member 7
chr1_-_52190901 0.366 ENSMUST00000156887.1
ENSMUST00000129107.1
 Gls

glutaminase

chr3_-_41742471 0.363 ENSMUST00000026866.8
 Sclt1
sodium channel and clathrin linker 1
chr3_+_41742615 0.352 ENSMUST00000146165.1
ENSMUST00000119572.1
ENSMUST00000108065.2
ENSMUST00000120167.1
ENSMUST00000026867.7
ENSMUST00000026868.7
 D3Ertd751e





DNA segment, Chr 3, ERATO Doi 751, expressed





chr7_+_27486910 0.327 ENSMUST00000008528.7
 Sertad1
SERTA domain containing 1
chrX_-_143933089 0.315 ENSMUST00000087313.3
 Dcx
doublecortin
chr8_+_69659263 0.282 ENSMUST00000169125.1
 Zfp964
zinc finger protein 964
chr4_+_102254739 0.274 ENSMUST00000106907.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr15_+_44787746 0.267 ENSMUST00000181839.1
 2310069G16Rik
RIKEN cDNA 2310069G16 gene
chrX_-_143933204 0.261 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
 Dcx


doublecortin


chrM_+_9870 0.246 ENSMUST00000084013.1
 mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr5_+_14514918 0.241 ENSMUST00000030691.10
ENSMUST00000182407.1
 Pclo

piccolo (presynaptic cytomatrix protein)

chrM_+_9452 0.232 ENSMUST00000082411.1
 mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr16_+_49699198 0.221 ENSMUST00000046777.4
ENSMUST00000142682.1
 Ift57

intraflagellar transport 57


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.9 GO:0019532 oxalate transport(GO:0019532)
0.0 0.6 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 0.5 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.5 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.3 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.2 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.2 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.2 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.0 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)

Gene overrepresentation in cellular_component category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.4 GO:0071439 clathrin complex(GO:0071439)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.2 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.0 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)

Gene overrepresentation in molecular_function category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.3 GO:0017161 phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.1 GO:0051378 primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)