Motif ID: Msx3

Z-value: 0.474


Transcription factors associated with Msx3:

Gene SymbolEntrez IDGene Name
Msx3 ENSMUSG00000025469.9 Msx3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Msx3mm10_v2_chr7_-_140049140_140049180-0.293.2e-01Click!


Activity profile for motif Msx3.

activity profile for motif Msx3


Sorted Z-values histogram for motif Msx3

Sorted Z-values for motif Msx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Msx3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_72441852 0.640 ENSMUST00000162159.1
 Lrrc9
leucine rich repeat containing 9
chr12_+_72441933 0.613 ENSMUST00000161284.1
 Lrrc9
leucine rich repeat containing 9
chr17_+_21383725 0.555 ENSMUST00000056107.4
ENSMUST00000162659.1
 Zfp677

zinc finger protein 677

chr2_-_45117349 0.494 ENSMUST00000176438.2
 Zeb2
zinc finger E-box binding homeobox 2
chr13_-_29984219 0.469 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3
chr4_-_14621494 0.393 ENSMUST00000149633.1
 Slc26a7
solute carrier family 26, member 7
chr4_-_14621669 0.380 ENSMUST00000143105.1
 Slc26a7
solute carrier family 26, member 7
chr1_-_52190901 0.366 ENSMUST00000156887.1
ENSMUST00000129107.1
 Gls

glutaminase

chr3_-_41742471 0.363 ENSMUST00000026866.8
 Sclt1
sodium channel and clathrin linker 1
chr3_+_41742615 0.352 ENSMUST00000146165.1
ENSMUST00000119572.1
ENSMUST00000108065.2
ENSMUST00000120167.1
ENSMUST00000026867.7
ENSMUST00000026868.7
 D3Ertd751e





DNA segment, Chr 3, ERATO Doi 751, expressed





chr7_+_27486910 0.327 ENSMUST00000008528.7
 Sertad1
SERTA domain containing 1
chrX_-_143933089 0.315 ENSMUST00000087313.3
 Dcx
doublecortin
chr8_+_69659263 0.282 ENSMUST00000169125.1
 Zfp964
zinc finger protein 964
chr4_+_102254739 0.274 ENSMUST00000106907.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr15_+_44787746 0.267 ENSMUST00000181839.1
 2310069G16Rik
RIKEN cDNA 2310069G16 gene
chrX_-_143933204 0.261 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
 Dcx


doublecortin


chrM_+_9870 0.246 ENSMUST00000084013.1
 mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr5_+_14514918 0.241 ENSMUST00000030691.10
ENSMUST00000182407.1
 Pclo

piccolo (presynaptic cytomatrix protein)

chrM_+_9452 0.232 ENSMUST00000082411.1
 mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr16_+_49699198 0.221 ENSMUST00000046777.4
ENSMUST00000142682.1
 Ift57

intraflagellar transport 57

chrX_-_75578188 0.210 ENSMUST00000033545.5
 Rab39b
RAB39B, member RAS oncogene family
chrM_+_7005 0.196 ENSMUST00000082405.1
 mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr1_-_172027269 0.184 ENSMUST00000027837.6
ENSMUST00000111264.1
 Vangl2

vang-like 2 (van gogh, Drosophila)

chr2_+_121956651 0.184 ENSMUST00000110574.1
 Ctdspl2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr10_-_85127977 0.170 ENSMUST00000050813.2
 Mterfd3
MTERF domain containing 3
chr13_-_58354862 0.165 ENSMUST00000043605.5
 Kif27
kinesin family member 27
chr12_+_71136848 0.164 ENSMUST00000149564.1
ENSMUST00000045907.8
 2700049A03Rik

RIKEN cDNA 2700049A03 gene

chr10_-_76110956 0.152 ENSMUST00000120757.1
 Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr9_-_15301555 0.141 ENSMUST00000034414.8
 4931406C07Rik
RIKEN cDNA 4931406C07 gene
chrX_+_16619698 0.140 ENSMUST00000026013.5
 Maoa
monoamine oxidase A
chr5_+_88583527 0.135 ENSMUST00000031229.6
 Rufy3
RUN and FYVE domain containing 3
chr4_-_14621805 0.132 ENSMUST00000042221.7
 Slc26a7
solute carrier family 26, member 7
chr9_-_53975246 0.131 ENSMUST00000048409.7
 Elmod1
ELMO/CED-12 domain containing 1
chr12_-_84617326 0.126 ENSMUST00000021666.4
 Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr4_-_58912678 0.125 ENSMUST00000144512.1
ENSMUST00000102889.3
ENSMUST00000055822.8
 AI314180


expressed sequence AI314180


chrX_-_60893430 0.114 ENSMUST00000135107.2
 Sox3
SRY-box containing gene 3
chr2_+_121956411 0.111 ENSMUST00000110578.1
 Ctdspl2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr3_-_116253467 0.106 ENSMUST00000090473.5
 Gpr88
G-protein coupled receptor 88
chr10_+_88379127 0.104 ENSMUST00000127615.1
 Gnptab
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr3_+_138374121 0.093 ENSMUST00000171054.1
 Adh6-ps1
alcohol dehydrogenase 6 (class V), pseudogene 1
chr16_-_75766758 0.089 ENSMUST00000114244.1
ENSMUST00000046283.8
 Hspa13

heat shock protein 70 family, member 13

chr9_+_100597686 0.081 ENSMUST00000124487.1
 Stag1
stromal antigen 1
chr7_+_103550368 0.079 ENSMUST00000106888.1
 Olfr613
olfactory receptor 613
chr9_+_35423582 0.068 ENSMUST00000154652.1
 Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr2_-_168767136 0.068 ENSMUST00000029061.5
ENSMUST00000103074.1
 Sall4

sal-like 4 (Drosophila)

chr2_-_20943413 0.058 ENSMUST00000140230.1
 Arhgap21
Rho GTPase activating protein 21
chr7_-_99141068 0.052 ENSMUST00000037968.8
 Uvrag
UV radiation resistance associated gene
chr10_+_39612934 0.050 ENSMUST00000019987.6
 Traf3ip2
TRAF3 interacting protein 2
chrX_+_107255878 0.049 ENSMUST00000101294.2
ENSMUST00000118820.1
ENSMUST00000120971.1
 Gpr174


G protein-coupled receptor 174


chr1_-_34439672 0.049 ENSMUST00000042493.8
 Ccdc115
coiled-coil domain containing 115
chr15_+_38661904 0.048 ENSMUST00000022904.6
 Atp6v1c1
ATPase, H+ transporting, lysosomal V1 subunit C1
chr13_+_83732438 0.047 ENSMUST00000182701.1
 C130071C03Rik
RIKEN cDNA C130071C03 gene
chr12_-_71136611 0.045 ENSMUST00000021486.8
ENSMUST00000166120.1
 Timm9

translocase of inner mitochondrial membrane 9

chr3_+_32515295 0.039 ENSMUST00000029203.7
 Zfp639
zinc finger protein 639
chr1_+_34439851 0.024 ENSMUST00000027303.7
 Imp4
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr15_+_82252397 0.023 ENSMUST00000136948.1
 1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr10_+_88379217 0.012 ENSMUST00000130301.1
ENSMUST00000020251.8
 Gnptab

N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits

chr3_+_66985947 0.012 ENSMUST00000161726.1
ENSMUST00000160504.1
 Rsrc1

arginine/serine-rich coiled-coil 1

chr13_-_102958084 0.007 ENSMUST00000099202.3
ENSMUST00000172264.1
 Mast4

microtubule associated serine/threonine kinase family member 4

chrX_+_9885622 0.007 ENSMUST00000067529.2
ENSMUST00000086165.3
 Sytl5

synaptotagmin-like 5

chr3_+_94837533 0.006 ENSMUST00000107270.2
 Pogz
pogo transposable element with ZNF domain
chr3_+_66985680 0.000 ENSMUST00000065047.6
 Rsrc1
arginine/serine-rich coiled-coil 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0019532 oxalate transport(GO:0019532)
0.1 0.5 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.5 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.2 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.2 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.6 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.2 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.3 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.0 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.2 GO:0060187 cell pole(GO:0060187)
0.0 0.4 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.2 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.0 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0051378 primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0017161 phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)