Motif ID: Mtf1

Z-value: 1.107


Transcription factors associated with Mtf1:

Gene SymbolEntrez IDGene Name
Mtf1 ENSMUSG00000028890.7 Mtf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mtf1mm10_v2_chr4_+_124802543_1248026780.039.1e-01Click!


Activity profile for motif Mtf1.

activity profile for motif Mtf1


Sorted Z-values histogram for motif Mtf1

Sorted Z-values for motif Mtf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Mtf1

PNG image of the network

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Top targets:


Showing 1 to 20 of 78 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_94172618 18.323 ENSMUST00000034214.6
Mt2
metallothionein 2
chr8_+_94179089 9.876 ENSMUST00000034215.6
Mt1
metallothionein 1
chr11_-_32222233 7.188 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
Rhbdf1


rhomboid family 1 (Drosophila)


chr1_+_135729147 2.838 ENSMUST00000027677.7
Csrp1
cysteine and glycine-rich protein 1
chr1_+_167618246 2.442 ENSMUST00000111380.1
Rxrg
retinoid X receptor gamma
chr6_-_39118211 2.357 ENSMUST00000038398.6
Parp12
poly (ADP-ribose) polymerase family, member 12
chr2_+_119112793 1.993 ENSMUST00000140939.1
ENSMUST00000028795.3
Rad51

RAD51 homolog

chr11_+_63133068 1.956 ENSMUST00000108700.1
Pmp22
peripheral myelin protein 22
chr10_+_77606571 1.537 ENSMUST00000099538.5
Sumo3
SMT3 suppressor of mif two 3 homolog 3 (yeast)
chr12_+_33957645 1.518 ENSMUST00000049089.5
Twist1
twist basic helix-loop-helix transcription factor 1
chr9_-_112187898 1.489 ENSMUST00000178410.1
ENSMUST00000172380.3
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr19_-_4615647 1.459 ENSMUST00000113822.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr3_+_107895821 1.428 ENSMUST00000004134.4
Gstm5
glutathione S-transferase, mu 5
chr11_+_63132569 1.423 ENSMUST00000108701.1
Pmp22
peripheral myelin protein 22
chr3_+_107895916 1.413 ENSMUST00000172247.1
ENSMUST00000167387.1
Gstm5

glutathione S-transferase, mu 5

chr19_-_4615453 1.343 ENSMUST00000053597.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr10_+_17723220 1.214 ENSMUST00000038107.7
Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr15_-_58214882 1.132 ENSMUST00000022986.6
Fbxo32
F-box protein 32
chr1_-_169531343 1.117 ENSMUST00000028000.7
Nuf2
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr14_-_26170283 1.113 ENSMUST00000100809.4
Plac9b
placenta specific 9b

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.0 28.2 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 7.2 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.6 3.9 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.2 3.4 GO:0032060 bleb assembly(GO:0032060)
0.0 2.8 GO:0070527 platelet aggregation(GO:0070527)
0.1 2.7 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.1 2.4 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.5 2.0 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 2.0 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.5 1.5 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.0 1.5 GO:0034605 cellular response to heat(GO:0034605)
0.3 1.3 GO:0042891 antibiotic transport(GO:0042891)
0.3 1.2 GO:0061428 embryonic heart tube left/right pattern formation(GO:0060971) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.4 1.1 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.2 1.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 1.1 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.3 0.9 GO:0097402 neuroblast migration(GO:0097402)
0.1 0.9 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.9 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.7 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.0 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 6.7 GO:0000139 Golgi membrane(GO:0000139)
0.3 3.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 3.4 GO:0043218 compact myelin(GO:0043218)
0.3 2.0 GO:0031262 Ndc80 complex(GO:0031262)
0.2 2.0 GO:0000800 lateral element(GO:0000800)
0.0 1.3 GO:0031526 brush border membrane(GO:0031526)
0.0 1.1 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 0.7 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 14.8 GO:0008270 zinc ion binding(GO:0008270)
0.2 10.2 GO:0005507 copper ion binding(GO:0005507)
0.1 7.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 3.9 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.2 2.7 GO:0031386 protein tag(GO:0031386)
0.2 2.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 2.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3 2.0 GO:0000150 recombinase activity(GO:0000150)
0.0 1.5 GO:0043425 bHLH transcription factor binding(GO:0043425) E-box binding(GO:0070888)
0.3 1.3 GO:0042895 antibiotic transporter activity(GO:0042895)
0.2 1.2 GO:0050693 LBD domain binding(GO:0050693)
0.4 1.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 1.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.9 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 0.7 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.7 GO:0019215 intermediate filament binding(GO:0019215)
0.2 0.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)