Motif ID: Mybl2

Z-value: 1.139


Transcription factors associated with Mybl2:

Gene SymbolEntrez IDGene Name
Mybl2 ENSMUSG00000017861.5 Mybl2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mybl2mm10_v2_chr2_+_163054682_163054693-0.204.8e-01Click!


Activity profile for motif Mybl2.

activity profile for motif Mybl2


Sorted Z-values histogram for motif Mybl2

Sorted Z-values for motif Mybl2



Network of associatons between targets according to the STRING database.



First level regulatory network of Mybl2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_+_1010543 3.638 ENSMUST00000091197.3
Eif2s3y
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chrY_-_1245685 3.016 ENSMUST00000143286.1
ENSMUST00000137048.1
ENSMUST00000069309.7
ENSMUST00000139365.1
Uty



ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome



chr2_+_29124106 2.452 ENSMUST00000129544.1
Setx
senataxin
chr18_+_34247685 1.961 ENSMUST00000066133.6
Apc
adenomatosis polyposis coli
chrY_-_1245753 1.817 ENSMUST00000154004.1
Uty
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr15_-_13173607 1.741 ENSMUST00000036439.4
Cdh6
cadherin 6
chr8_+_84415348 1.245 ENSMUST00000121390.1
ENSMUST00000122053.1
Cacna1a

calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

chr4_-_115133977 1.216 ENSMUST00000051400.7
Cyp4x1
cytochrome P450, family 4, subfamily x, polypeptide 1
chr11_+_106160850 1.126 ENSMUST00000100326.1
Gm10840
predicted gene 10840
chr13_-_21531032 1.095 ENSMUST00000156674.2
ENSMUST00000110481.2
Zkscan8

zinc finger with KRAB and SCAN domains 8

chr4_+_100478806 1.088 ENSMUST00000133493.2
ENSMUST00000092730.3
ENSMUST00000106979.3
Ube2u


ubiquitin-conjugating enzyme E2U (putative)


chr9_+_96119362 1.012 ENSMUST00000085217.5
ENSMUST00000122383.1
Gk5

glycerol kinase 5 (putative)

chr14_+_61172966 1.000 ENSMUST00000121091.1
Sacs
sacsin
chr3_+_104638658 0.980 ENSMUST00000046212.1
Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr9_+_75071579 0.973 ENSMUST00000136731.1
Myo5a
myosin VA
chr1_-_169747634 0.921 ENSMUST00000027991.5
ENSMUST00000111357.1
Rgs4

regulator of G-protein signaling 4

chr1_-_155099630 0.865 ENSMUST00000055322.4
Ier5
immediate early response 5
chr13_-_59675754 0.844 ENSMUST00000022039.5
ENSMUST00000095739.2
Golm1

golgi membrane protein 1

chr3_+_26331150 0.832 ENSMUST00000099182.2
A830092H15Rik
RIKEN cDNA A830092H15 gene
chr10_+_69534039 0.823 ENSMUST00000182557.1
Ank3
ankyrin 3, epithelial

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 118 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 4.8 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.3 3.6 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.5 2.5 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.5 2.0 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.0 1.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.6 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 1.3 GO:0006071 glycerol metabolic process(GO:0006071)
0.4 1.2 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 1.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.1 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 1.1 GO:0016574 histone ubiquitination(GO:0016574)
0.2 1.0 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.0 1.0 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 1.0 GO:0007099 centriole replication(GO:0007099)
0.1 0.9 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.9 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.3 0.8 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.8 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.8 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.8 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.1 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 2.3 GO:0043204 perikaryon(GO:0043204)
0.2 2.0 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 1.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 1.1 GO:0033503 HULC complex(GO:0033503)
0.3 1.0 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.1 0.9 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.3 0.8 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.8 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.7 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.6 GO:0042611 MHC protein complex(GO:0042611)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.5 GO:0045098 type III intermediate filament(GO:0045098)
0.1 0.5 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.5 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.5 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 87 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 4.8 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 4.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.6 GO:0042393 histone binding(GO:0042393)
0.8 2.5 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 2.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.2 GO:0030553 cGMP binding(GO:0030553)
0.0 1.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 1.0 GO:0043422 protein kinase B binding(GO:0043422)
0.0 1.0 GO:0017161 phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.0 1.0 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 1.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.3 0.8 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.2 0.8 GO:0070330 aromatase activity(GO:0070330)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.8 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.7 GO:0019789 SUMO transferase activity(GO:0019789)