Motif ID: Mzf1

Z-value: 1.187


Transcription factors associated with Mzf1:

Gene SymbolEntrez IDGene Name
Mzf1 ENSMUSG00000030380.10 Mzf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mzf1mm10_v2_chr7_-_13054665_13054764-0.573.2e-02Click!


Activity profile for motif Mzf1.

activity profile for motif Mzf1


Sorted Z-values histogram for motif Mzf1

Sorted Z-values for motif Mzf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Mzf1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_95514570 3.853 ENSMUST00000058866.7
 Nxph3
neurexophilin 3
chr14_-_12345847 3.535 ENSMUST00000022262.4
 Fezf2
Fez family zinc finger 2
chr3_+_103575231 2.776 ENSMUST00000121834.1
 Syt6
synaptotagmin VI
chr1_-_154725920 2.678 ENSMUST00000004214.8
 Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr3_+_103575275 2.645 ENSMUST00000090697.4
 Syt6
synaptotagmin VI
chr5_-_24601961 2.625 ENSMUST00000030791.7
 Smarcd3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr4_-_68954351 2.325 ENSMUST00000030036.5
 Brinp1
bone morphogenic protein/retinoic acid inducible neural specific 1
chr14_-_102982630 2.320 ENSMUST00000184744.1
 KCTD12
mmu-mir-5130
chr9_+_34486125 2.109 ENSMUST00000115148.2
ENSMUST00000183580.1
 Kirrel3
RP24-225I21.1
kin of IRRE like 3 (Drosophila)
RP24-225I21.1
chr3_+_96596628 2.085 ENSMUST00000058943.7
 Ankrd34a
ankyrin repeat domain 34A
chr14_-_39472825 1.908 ENSMUST00000168810.2
ENSMUST00000173780.1
ENSMUST00000166968.2
 Nrg3


neuregulin 3


chr3_+_103576081 1.789 ENSMUST00000183637.1
ENSMUST00000117221.2
ENSMUST00000118117.1
ENSMUST00000118563.2
 Syt6



synaptotagmin VI



chr1_+_153652943 1.770 ENSMUST00000041776.5
 Rgs8
regulator of G-protein signaling 8
chr8_-_87959560 1.735 ENSMUST00000109655.2
 Zfp423
zinc finger protein 423
chr15_-_12592556 1.722 ENSMUST00000075317.5
 Pdzd2
PDZ domain containing 2
chr12_-_81333129 1.708 ENSMUST00000085238.6
ENSMUST00000182208.1
 Slc8a3

solute carrier family 8 (sodium/calcium exchanger), member 3

chr10_+_13966268 1.699 ENSMUST00000015645.4
 Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr6_-_126740151 1.606 ENSMUST00000112242.1
 Kcna6
potassium voltage-gated channel, shaker-related, subfamily, member 6
chr3_+_102735202 1.604 ENSMUST00000119902.1
 Tspan2
tetraspanin 2
chr1_+_167001457 1.598 ENSMUST00000126198.1
 Fam78b
family with sequence similarity 78, member B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 268 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.4 7.2 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.6 5.4 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830)
0.2 3.9 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.5 2.7 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.1 2.7 GO:0071625 vocalization behavior(GO:0071625)
0.9 2.6 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.5 2.5 GO:2000587 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1 2.5 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.8 2.4 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.4 2.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.5 2.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.4 2.1 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.3 2.1 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.1 2.1 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 2.0 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 2.0 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.2 1.9 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2 1.8 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 1.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.6 1.7 GO:1990034 calcium ion export from cell(GO:1990034)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 118 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 16.3 GO:0060076 excitatory synapse(GO:0060076)
0.3 8.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 4.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 4.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 2.8 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 2.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 2.7 GO:0043083 synaptic cleft(GO:0043083)
0.1 2.7 GO:0071564 npBAF complex(GO:0071564)
0.0 2.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 2.7 GO:0043209 myelin sheath(GO:0043209)
0.1 2.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 2.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.9 GO:1990391 DNA repair complex(GO:1990391)
0.0 1.8 GO:0045202 synapse(GO:0045202)
0.1 1.7 GO:0043196 varicosity(GO:0043196)
0.1 1.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.7 GO:0070822 Sin3-type complex(GO:0070822)
0.0 1.6 GO:0034399 nuclear periphery(GO:0034399)
0.0 1.6 GO:0000776 kinetochore(GO:0000776)
0.1 1.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 170 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 8.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.3 3.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 2.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 2.8 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 2.8 GO:0008017 microtubule binding(GO:0008017)
0.1 2.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 2.6 GO:0019210 kinase inhibitor activity(GO:0019210)
0.3 2.4 GO:0001618 virus receptor activity(GO:0001618)
0.1 2.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 2.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 2.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 2.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.5 2.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 2.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 2.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.2 1.9 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 1.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.8 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)