Motif ID: Nanog

Z-value: 1.615


Transcription factors associated with Nanog:

Gene SymbolEntrez IDGene Name
Nanog ENSMUSG00000012396.6 Nanog

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nanogmm10_v2_chr6_+_122707489_122707608-0.019.7e-01Click!


Activity profile for motif Nanog.

activity profile for motif Nanog


Sorted Z-values histogram for motif Nanog

Sorted Z-values for motif Nanog



Network of associatons between targets according to the STRING database.



First level regulatory network of Nanog

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_52490736 7.801 ENSMUST00000170269.1
 Nab1
Ngfi-A binding protein 1
chr15_-_93519499 7.616 ENSMUST00000109255.2
 Prickle1
prickle homolog 1 (Drosophila)
chr14_-_12345847 5.708 ENSMUST00000022262.4
 Fezf2
Fez family zinc finger 2
chr12_+_72441933 5.055 ENSMUST00000161284.1
 Lrrc9
leucine rich repeat containing 9
chr6_+_80018877 4.800 ENSMUST00000147663.1
ENSMUST00000128718.1
ENSMUST00000126005.1
ENSMUST00000133918.1
 Lrrtm4



leucine rich repeat transmembrane neuronal 4



chr19_+_25672408 4.795 ENSMUST00000053068.5
 Dmrt2
doublesex and mab-3 related transcription factor 2
chr6_+_80019008 4.705 ENSMUST00000126399.1
ENSMUST00000136421.1
 Lrrtm4

leucine rich repeat transmembrane neuronal 4

chr12_+_72441852 4.157 ENSMUST00000162159.1
 Lrrc9
leucine rich repeat containing 9
chr1_-_158814469 3.235 ENSMUST00000161589.2
 Pappa2
pappalysin 2
chr5_-_147076482 3.099 ENSMUST00000016664.7
 Lnx2
ligand of numb-protein X 2
chr13_-_89742244 3.030 ENSMUST00000109543.2
ENSMUST00000159337.1
ENSMUST00000159910.1
ENSMUST00000109544.2
 Vcan



versican



chr13_-_89742490 2.991 ENSMUST00000109546.2
 Vcan
versican
chrX_+_153237466 2.411 ENSMUST00000143880.1
 Klf8
Kruppel-like factor 8
chr12_-_83487708 2.104 ENSMUST00000177959.1
ENSMUST00000178756.1
 Dpf3

D4, zinc and double PHD fingers, family 3

chr11_-_109298066 1.931 ENSMUST00000106706.1
 Rgs9
regulator of G-protein signaling 9
chr15_-_13173607 1.835 ENSMUST00000036439.4
 Cdh6
cadherin 6
chr17_+_3397189 1.832 ENSMUST00000072156.6
 Tiam2
T cell lymphoma invasion and metastasis 2
chr8_-_36732897 1.821 ENSMUST00000098826.3
 Dlc1
deleted in liver cancer 1
chr7_+_67647405 1.764 ENSMUST00000032774.8
ENSMUST00000107471.1
 Ttc23

tetratricopeptide repeat domain 23

chr11_+_75532099 1.668 ENSMUST00000169547.2
 Slc43a2
solute carrier family 43, member 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 114 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 9.5 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.2 7.8 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
2.5 7.6 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.1 6.2 GO:0008347 glial cell migration(GO:0008347)
1.0 5.7 GO:1904936 forebrain anterior/posterior pattern specification(GO:0021797) cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
1.2 4.8 GO:0061055 myotome development(GO:0061055)
0.1 3.7 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 3.2 GO:0060349 bone morphogenesis(GO:0060349)
0.8 3.1 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.5 2.7 GO:0072318 clathrin coat disassembly(GO:0072318)
0.0 2.2 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 2.1 GO:0098792 xenophagy(GO:0098792)
0.2 1.8 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.4 1.7 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.4 1.6 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.2 1.6 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 1.6 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.5 1.5 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.2 1.4 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 1.4 GO:0000185 activation of MAPKKK activity(GO:0000185)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 9.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 7.4 GO:0031965 nuclear membrane(GO:0031965)
0.1 3.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 3.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 2.4 GO:0043198 dendritic shaft(GO:0043198)
0.1 2.1 GO:0071565 nBAF complex(GO:0071565)
0.0 2.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.8 GO:0032587 ruffle membrane(GO:0032587)
0.1 1.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 1.3 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 1.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.3 GO:0005902 microvillus(GO:0005902)
0.3 1.1 GO:0060187 cell pole(GO:0060187)
0.1 1.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.1 GO:0030018 Z disc(GO:0030018)
0.1 1.0 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.2 0.9 GO:0032541 cortical endoplasmic reticulum(GO:0032541)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 91 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.1 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.4 9.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 7.0 GO:0008134 transcription factor binding(GO:0008134)
0.3 5.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 3.3 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
1.0 3.1 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.0 3.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.8 GO:0030165 PDZ domain binding(GO:0030165)
0.0 2.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.9 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.0 1.9 GO:0005057 receptor signaling protein activity(GO:0005057)
0.1 1.8 GO:0017166 vinculin binding(GO:0017166)
0.3 1.6 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.2 1.6 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 1.6 GO:0045296 cadherin binding(GO:0045296)
0.1 1.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.4 GO:0001047 core promoter binding(GO:0001047)
0.1 1.3 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.0 1.3 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.3 GO:0015485 cholesterol binding(GO:0015485)