Motif ID: Neurod2_Bhlha15_Bhlhe22_Olig1

Z-value: 0.862

Transcription factors associated with Neurod2_Bhlha15_Bhlhe22_Olig1:

Gene SymbolEntrez IDGene Name
Bhlha15 ENSMUSG00000052271.7 Bhlha15
Bhlhe22 ENSMUSG00000025128.6 Bhlhe22
Neurod2 ENSMUSG00000038255.6 Neurod2
Olig1 ENSMUSG00000046160.5 Olig1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Neurod2mm10_v2_chr11_-_98329641_983296540.401.6e-01Click!
Bhlhe22mm10_v2_chr3_+_18054258_180543250.352.2e-01Click!
Olig1mm10_v2_chr16_+_91269759_91269778-0.214.8e-01Click!


Activity profile for motif Neurod2_Bhlha15_Bhlhe22_Olig1.

activity profile for motif Neurod2_Bhlha15_Bhlhe22_Olig1


Sorted Z-values histogram for motif Neurod2_Bhlha15_Bhlhe22_Olig1

Sorted Z-values for motif Neurod2_Bhlha15_Bhlhe22_Olig1



Network of associatons between targets according to the STRING database.



First level regulatory network of Neurod2_Bhlha15_Bhlhe22_Olig1

PNG image of the network

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Top targets:


Showing 1 to 20 of 162 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_42035113 2.220 ENSMUST00000098127.1
 Gm10597
predicted gene 10597
chr4_-_42034726 2.190 ENSMUST00000084677.2
 Gm21093
predicted gene, 21093
chr11_-_75796048 2.027 ENSMUST00000021209.7
 Doc2b
double C2, beta
chr2_+_65930117 2.012 ENSMUST00000176109.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr4_+_42714926 2.003 ENSMUST00000178454.1
 Gm21955
predicted gene, 21955
chr5_+_124194894 1.877 ENSMUST00000159053.1
ENSMUST00000162577.1
 Gm16338

predicted gene 16338

chr4_+_86053887 1.624 ENSMUST00000107178.2
ENSMUST00000048885.5
ENSMUST00000141889.1
ENSMUST00000120678.1
 Adamtsl1



ADAMTS-like 1



chr3_+_138065052 1.550 ENSMUST00000163080.2
 1110002E22Rik
RIKEN cDNA 1110002E22 gene
chr1_-_150392719 1.514 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
 BC003331


cDNA sequence BC003331


chr3_-_126998408 1.462 ENSMUST00000182764.1
ENSMUST00000044443.8
 Ank2

ankyrin 2, brain

chr5_-_66618636 1.330 ENSMUST00000162382.1
ENSMUST00000160870.1
ENSMUST00000087256.5
ENSMUST00000160103.1
ENSMUST00000162349.1
 Apbb2




amyloid beta (A4) precursor protein-binding, family B, member 2




chr13_-_62607499 1.286 ENSMUST00000091563.4
 6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr4_-_110292719 1.150 ENSMUST00000106601.1
 Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr15_-_76126538 1.121 ENSMUST00000054022.5
ENSMUST00000089654.3
 BC024139

cDNA sequence BC024139

chr8_+_25601591 1.047 ENSMUST00000155861.1
 Whsc1l1
Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
chr3_-_27710413 1.046 ENSMUST00000046157.4
 Fndc3b
fibronectin type III domain containing 3B
chr2_+_150323702 1.002 ENSMUST00000133235.2
 Gm10130
predicted gene 10130
chr11_+_58954675 0.833 ENSMUST00000047697.5
ENSMUST00000108817.3
 Trim17
Hist3h2a
tripartite motif-containing 17
histone cluster 3, H2a
chr9_+_72985504 0.813 ENSMUST00000156879.1
 Ccpg1
cell cycle progression 1
chr8_+_25602236 0.798 ENSMUST00000146919.1
ENSMUST00000142395.1
ENSMUST00000139966.1
 Whsc1l1


Wolf-Hirschhorn syndrome candidate 1-like 1 (human)



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 2.0 GO:0045956 positive regulation of vesicle fusion(GO:0031340) positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 2.0 GO:0030048 actin filament-based movement(GO:0030048)
0.1 1.9 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.4 1.5 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 1.5 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 1.5 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 1.1 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 1.0 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.1 0.8 GO:0070914 UV-damage excision repair(GO:0070914)
0.2 0.7 GO:0002159 desmosome assembly(GO:0002159) adherens junction maintenance(GO:0034334) intermediate filament bundle assembly(GO:0045110) maintenance of organ identity(GO:0048496)
0.1 0.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.7 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 0.6 GO:2000302 regulation of synaptic vesicle endocytosis(GO:1900242) positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.0 0.6 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.6 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.2 0.5 GO:0048211 Golgi vesicle docking(GO:0048211)
0.0 0.5 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.5 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.4 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.0 GO:0031201 SNARE complex(GO:0031201)
0.1 1.7 GO:0031430 M band(GO:0031430)
0.1 1.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.1 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.7 GO:0030057 desmosome(GO:0030057)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.4 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.3 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.1 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.0 GO:0071942 XPC complex(GO:0071942)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.3 1.8 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2 1.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 1.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.1 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.9 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.5 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.3 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.3 GO:0045703 pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.0 0.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.3 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)