Motif ID: Neurog2

Z-value: 0.518


Transcription factors associated with Neurog2:

Gene SymbolEntrez IDGene Name
Neurog2 ENSMUSG00000027967.7 Neurog2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Neurog2mm10_v2_chr3_+_127633134_127633140-0.469.8e-02Click!


Activity profile for motif Neurog2.

activity profile for motif Neurog2


Sorted Z-values histogram for motif Neurog2

Sorted Z-values for motif Neurog2



Network of associatons between targets according to the STRING database.



First level regulatory network of Neurog2

PNG image of the network

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Top targets:


Showing 1 to 20 of 160 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_54156039 1.046 ENSMUST00000029311.6
Trpc4
transient receptor potential cation channel, subfamily C, member 4
chr13_-_97747373 0.916 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr3_+_118430299 0.915 ENSMUST00000180774.1
Gm26871
predicted gene, 26871
chr1_+_42697146 0.911 ENSMUST00000054883.2
Pou3f3
POU domain, class 3, transcription factor 3
chr3_-_59220150 0.880 ENSMUST00000170388.1
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr4_-_141598206 0.756 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
Fblim1


filamin binding LIM protein 1


chr13_+_37345338 0.711 ENSMUST00000021860.5
Ly86
lymphocyte antigen 86
chr17_-_25792284 0.631 ENSMUST00000072735.7
Fam173a
family with sequence similarity 173, member A
chr2_-_79456750 0.631 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr11_-_69805617 0.611 ENSMUST00000051025.4
Tmem102
transmembrane protein 102
chr1_+_165763746 0.561 ENSMUST00000111432.3
Creg1
cellular repressor of E1A-stimulated genes 1
chr16_+_43235856 0.497 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr1_-_111864869 0.495 ENSMUST00000035462.5
Dsel
dermatan sulfate epimerase-like
chrX_-_7188713 0.474 ENSMUST00000004428.7
Clcn5
chloride channel 5
chr11_+_53433299 0.459 ENSMUST00000018382.6
Gdf9
growth differentiation factor 9
chr8_+_33428709 0.450 ENSMUST00000059351.7
5930422O12Rik
RIKEN cDNA 5930422O12 gene
chr16_-_31314804 0.449 ENSMUST00000115230.1
ENSMUST00000130560.1
Apod

apolipoprotein D

chrX_+_56786527 0.442 ENSMUST00000144600.1
Fhl1
four and a half LIM domains 1
chr10_-_70655934 0.417 ENSMUST00000162144.1
ENSMUST00000162793.1
Phyhipl

phytanoyl-CoA hydroxylase interacting protein-like

chrX_-_53608979 0.416 ENSMUST00000123034.1
Gm14597
predicted gene 14597

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.0 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.3 0.9 GO:0072070 loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.3 0.9 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 0.8 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.7 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.2 0.6 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.6 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.1 0.5 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.5 GO:2000194 regulation of female gonad development(GO:2000194)
0.0 0.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.5 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.4 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097) negative regulation of lymphocyte migration(GO:2000402)
0.1 0.4 GO:1902044 regulation of Fas signaling pathway(GO:1902044) negative regulation of Fas signaling pathway(GO:1902045)
0.1 0.4 GO:1903288 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.1 0.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.4 GO:0032796 uropod organization(GO:0032796)
0.1 0.4 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 GO:0034704 calcium channel complex(GO:0034704)
0.1 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.3 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.2 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:0044453 nuclear membrane part(GO:0044453)
0.0 0.1 GO:1990879 CST complex(GO:1990879)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0071837 HMG box domain binding(GO:0071837)
0.1 1.0 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 0.9 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.7 GO:0031005 filamin binding(GO:0031005)
0.0 0.6 GO:0010181 FMN binding(GO:0010181)
0.0 0.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.4 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.4 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.2 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 0.2 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)