Motif ID: Neurog2

Z-value: 0.518


Transcription factors associated with Neurog2:

Gene SymbolEntrez IDGene Name
Neurog2 ENSMUSG00000027967.7 Neurog2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Neurog2mm10_v2_chr3_+_127633134_127633140-0.469.8e-02Click!


Activity profile for motif Neurog2.

activity profile for motif Neurog2


Sorted Z-values histogram for motif Neurog2

Sorted Z-values for motif Neurog2



Network of associatons between targets according to the STRING database.



First level regulatory network of Neurog2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_54156039 1.046 ENSMUST00000029311.6
Trpc4
transient receptor potential cation channel, subfamily C, member 4
chr13_-_97747373 0.916 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr3_+_118430299 0.915 ENSMUST00000180774.1
Gm26871
predicted gene, 26871
chr1_+_42697146 0.911 ENSMUST00000054883.2
Pou3f3
POU domain, class 3, transcription factor 3
chr3_-_59220150 0.880 ENSMUST00000170388.1
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr4_-_141598206 0.756 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
Fblim1


filamin binding LIM protein 1


chr13_+_37345338 0.711 ENSMUST00000021860.5
Ly86
lymphocyte antigen 86
chr17_-_25792284 0.631 ENSMUST00000072735.7
Fam173a
family with sequence similarity 173, member A
chr2_-_79456750 0.631 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr11_-_69805617 0.611 ENSMUST00000051025.4
Tmem102
transmembrane protein 102
chr1_+_165763746 0.561 ENSMUST00000111432.3
Creg1
cellular repressor of E1A-stimulated genes 1
chr16_+_43235856 0.497 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr1_-_111864869 0.495 ENSMUST00000035462.5
Dsel
dermatan sulfate epimerase-like
chrX_-_7188713 0.474 ENSMUST00000004428.7
Clcn5
chloride channel 5
chr11_+_53433299 0.459 ENSMUST00000018382.6
Gdf9
growth differentiation factor 9
chr8_+_33428709 0.450 ENSMUST00000059351.7
5930422O12Rik
RIKEN cDNA 5930422O12 gene
chr16_-_31314804 0.449 ENSMUST00000115230.1
ENSMUST00000130560.1
Apod

apolipoprotein D

chrX_+_56786527 0.442 ENSMUST00000144600.1
Fhl1
four and a half LIM domains 1
chr10_-_70655934 0.417 ENSMUST00000162144.1
ENSMUST00000162793.1
Phyhipl

phytanoyl-CoA hydroxylase interacting protein-like

chrX_-_53608979 0.416 ENSMUST00000123034.1
Gm14597
predicted gene 14597
chr5_+_129096740 0.410 ENSMUST00000056617.7
ENSMUST00000156437.1
Gpr133

G protein-coupled receptor 133

chr10_+_56106883 0.409 ENSMUST00000063138.7
Msl3l2
male-specific lethal 3-like 2 (Drosophila)
chr9_-_70421533 0.407 ENSMUST00000034742.6
Ccnb2
cyclin B2
chr5_-_123141067 0.399 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
AI480526


expressed sequence AI480526


chr11_-_69602741 0.396 ENSMUST00000138694.1
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr19_-_53371766 0.395 ENSMUST00000086887.1
Gm10197
predicted gene 10197
chr9_-_88719798 0.383 ENSMUST00000113110.3
Gm2382
predicted gene 2382
chr10_-_22149270 0.371 ENSMUST00000179054.1
ENSMUST00000069372.6
E030030I06Rik

RIKEN cDNA E030030I06 gene

chr2_-_105399286 0.369 ENSMUST00000006128.6
Rcn1
reticulocalbin 1
chr19_+_20601958 0.364 ENSMUST00000087638.3
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr13_-_97747399 0.362 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr3_-_63851251 0.356 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
Plch1


phospholipase C, eta 1


chr1_-_74304386 0.335 ENSMUST00000016309.9
Tmbim1
transmembrane BAX inhibitor motif containing 1
chr9_-_71896047 0.325 ENSMUST00000184448.1
Tcf12
transcription factor 12
chr9_+_66946057 0.323 ENSMUST00000040917.7
ENSMUST00000127896.1
Rps27l

ribosomal protein S27-like

chr13_+_63282142 0.315 ENSMUST00000159152.1
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr12_-_84876479 0.315 ENSMUST00000163189.1
ENSMUST00000110254.2
ENSMUST00000002073.6
Ltbp2


latent transforming growth factor beta binding protein 2


chr1_+_136018062 0.302 ENSMUST00000117950.1
Tmem9
transmembrane protein 9
chr8_+_104170513 0.292 ENSMUST00000171018.1
ENSMUST00000167633.1
ENSMUST00000093245.5
ENSMUST00000164076.1
Bean1



brain expressed, associated with Nedd4, 1



chr1_+_136017967 0.274 ENSMUST00000063719.8
ENSMUST00000118832.1
Tmem9

transmembrane protein 9

chr7_+_6474088 0.270 ENSMUST00000056144.5
Olfr1346
olfactory receptor 1346
chr3_-_84259812 0.256 ENSMUST00000107691.1
Trim2
tripartite motif-containing 2
chr1_+_177444653 0.254 ENSMUST00000094276.3
Zbtb18
zinc finger and BTB domain containing 18
chr4_+_155839675 0.251 ENSMUST00000141883.1
Mxra8
matrix-remodelling associated 8
chr3_+_18054258 0.249 ENSMUST00000026120.6
Bhlhe22
basic helix-loop-helix family, member e22
chr8_+_122476196 0.239 ENSMUST00000146634.1
ENSMUST00000134127.1
Ctu2

cytosolic thiouridylase subunit 2 homolog (S. pombe)

chr8_+_114439655 0.236 ENSMUST00000004756.7
ENSMUST00000109108.2
ENSMUST00000160862.1
ENSMUST00000109107.2
Wwox



WW domain-containing oxidoreductase



chr19_-_37176055 0.234 ENSMUST00000142973.1
ENSMUST00000154376.1
Cpeb3

cytoplasmic polyadenylation element binding protein 3

chr10_-_12923075 0.233 ENSMUST00000180529.1
B230208H11Rik
RIKEN cDNA B230208H11 gene
chr5_+_124483458 0.231 ENSMUST00000111453.1
Snrnp35
small nuclear ribonucleoprotein 35 (U11/U12)
chr7_+_44748413 0.230 ENSMUST00000002275.8
Vrk3
vaccinia related kinase 3
chr4_+_11579647 0.230 ENSMUST00000180239.1
Fsbp
fibrinogen silencer binding protein
chr4_-_82850721 0.228 ENSMUST00000139401.1
Zdhhc21
zinc finger, DHHC domain containing 21
chr11_-_69920581 0.226 ENSMUST00000108610.1
Eif5a
eukaryotic translation initiation factor 5A
chr8_-_122476036 0.210 ENSMUST00000014614.3
Rnf166
ring finger protein 166
chr9_-_58158498 0.207 ENSMUST00000168864.2
Islr
immunoglobulin superfamily containing leucine-rich repeat
chr6_-_83033422 0.196 ENSMUST00000089651.5
Dok1
docking protein 1
chr17_+_46772635 0.196 ENSMUST00000071430.5
2310039H08Rik
RIKEN cDNA 2310039H08 gene
chr13_+_49544443 0.193 ENSMUST00000177948.1
ENSMUST00000021820.6
Aspn

asporin

chr7_-_139582790 0.192 ENSMUST00000106095.2
Nkx6-2
NK6 homeobox 2
chr5_-_108434373 0.187 ENSMUST00000049628.9
ENSMUST00000118632.1
Atp5k

ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit e

chr2_-_25501717 0.186 ENSMUST00000015227.3
C8g
complement component 8, gamma polypeptide
chr7_-_126704816 0.180 ENSMUST00000032949.7
Coro1a
coronin, actin binding protein 1A
chr11_+_49247462 0.180 ENSMUST00000109194.1
Mgat1
mannoside acetylglucosaminyltransferase 1
chr2_-_121807024 0.167 ENSMUST00000138157.1
Frmd5
FERM domain containing 5
chr18_+_55057557 0.166 ENSMUST00000181765.1
Gm4221
predicted gene 4221
chr4_+_105790534 0.166 ENSMUST00000185012.1
Gm12728
predicted gene 12728
chr10_+_80142358 0.165 ENSMUST00000105366.1
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr7_-_126704522 0.161 ENSMUST00000135087.1
Coro1a
coronin, actin binding protein 1A
chr6_+_51544513 0.159 ENSMUST00000179365.1
ENSMUST00000114439.1
Snx10

sorting nexin 10

chr7_+_30314810 0.158 ENSMUST00000054594.8
ENSMUST00000177078.1
ENSMUST00000176504.1
ENSMUST00000176304.1
Syne4



spectrin repeat containing, nuclear envelope family member 4



chrX_+_56454871 0.156 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr10_+_80142295 0.155 ENSMUST00000003156.8
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr10_+_74967164 0.146 ENSMUST00000037813.4
Gnaz
guanine nucleotide binding protein, alpha z subunit
chr3_+_138065052 0.145 ENSMUST00000163080.2
1110002E22Rik
RIKEN cDNA 1110002E22 gene
chr2_+_164456936 0.145 ENSMUST00000109352.1
Sys1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr9_-_75441652 0.142 ENSMUST00000181896.1
A130057D12Rik
RIKEN cDNA A130057D12 gene
chr10_-_25200110 0.138 ENSMUST00000100012.2
Akap7
A kinase (PRKA) anchor protein 7
chr9_+_37401993 0.135 ENSMUST00000115046.1
ENSMUST00000102895.4
Robo4

roundabout homolog 4 (Drosophila)

chr8_-_106337987 0.134 ENSMUST00000067512.7
Smpd3
sphingomyelin phosphodiesterase 3, neutral
chr18_+_74216118 0.129 ENSMUST00000025444.6
Cxxc1
CXXC finger 1 (PHD domain)
chr6_+_83034173 0.127 ENSMUST00000000707.2
ENSMUST00000101257.3
Loxl3

lysyl oxidase-like 3

chr2_-_39065438 0.125 ENSMUST00000112850.2
Golga1
golgi autoantigen, golgin subfamily a, 1
chr11_+_100320596 0.125 ENSMUST00000152521.1
Eif1
eukaryotic translation initiation factor 1
chr17_-_27623441 0.125 ENSMUST00000025050.5
Nudt3
nudix (nucleotide diphosphate linked moiety X)-type motif 3
chr8_+_122476143 0.125 ENSMUST00000116412.1
Ctu2
cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr11_+_32642706 0.124 ENSMUST00000109366.1
Fbxw11
F-box and WD-40 domain protein 11
chr9_-_26999491 0.121 ENSMUST00000060513.7
ENSMUST00000120367.1
Acad8

acyl-Coenzyme A dehydrogenase family, member 8

chrX_+_141475385 0.120 ENSMUST00000112931.1
ENSMUST00000112930.1
Col4a5

collagen, type IV, alpha 5

chr15_-_85811644 0.116 ENSMUST00000144067.1
ENSMUST00000134631.1
ENSMUST00000154814.1
ENSMUST00000071876.6
ENSMUST00000150995.1
Cdpf1




cysteine rich, DPF motif domain containing 1




chr1_-_74304345 0.112 ENSMUST00000113796.1
Tmbim1
transmembrane BAX inhibitor motif containing 1
chr11_+_69015911 0.112 ENSMUST00000021278.7
ENSMUST00000161455.1
ENSMUST00000116359.2
Ctc1


CTS telomere maintenance complex component 1


chr9_+_37401897 0.111 ENSMUST00000115048.1
Robo4
roundabout homolog 4 (Drosophila)
chr10_+_128232065 0.110 ENSMUST00000055539.4
ENSMUST00000105244.1
ENSMUST00000105243.2
ENSMUST00000125289.1
ENSMUST00000105242.1
Timeless




timeless circadian clock 1




chr17_-_27623263 0.109 ENSMUST00000062397.6
ENSMUST00000176876.1
Nudt3

nudix (nucleotide diphosphate linked moiety X)-type motif 3

chr11_-_69920892 0.109 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr9_+_108560422 0.101 ENSMUST00000081111.8
Impdh2
inosine 5'-phosphate dehydrogenase 2
chr9_+_26999668 0.100 ENSMUST00000039161.8
Thyn1
thymocyte nuclear protein 1
chr8_+_8689666 0.093 ENSMUST00000179702.1
B930078G14Rik
RIKEN cDNA B930078G14 gene
chr2_-_39065505 0.093 ENSMUST00000039165.8
Golga1
golgi autoantigen, golgin subfamily a, 1
chr7_-_126704736 0.093 ENSMUST00000131415.1
Coro1a
coronin, actin binding protein 1A
chr9_-_58159201 0.093 ENSMUST00000041477.7
Islr
immunoglobulin superfamily containing leucine-rich repeat
chrX_+_7579666 0.089 ENSMUST00000115740.1
ENSMUST00000115739.1
Foxp3

forkhead box P3

chr11_-_68853119 0.089 ENSMUST00000018880.7
Ndel1
nuclear distribution gene E-like homolog 1 (A. nidulans)
chr2_-_174346712 0.088 ENSMUST00000168292.1
Gm20721
predicted gene, 20721
chr11_-_68853019 0.081 ENSMUST00000108672.1
Ndel1
nuclear distribution gene E-like homolog 1 (A. nidulans)
chr18_+_50051702 0.081 ENSMUST00000134348.1
ENSMUST00000153873.2
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr11_-_84916338 0.080 ENSMUST00000103195.4
Znhit3
zinc finger, HIT type 3
chr7_-_28949670 0.080 ENSMUST00000148196.1
Actn4
actinin alpha 4
chr14_+_4665094 0.079 ENSMUST00000169675.2
Gm3239
predicted gene 3239
chr11_+_117232254 0.079 ENSMUST00000106354.2
Sept9
septin 9
chr1_-_155232710 0.078 ENSMUST00000035914.3
BC034090
cDNA sequence BC034090
chr3_-_63899437 0.078 ENSMUST00000159188.1
ENSMUST00000177143.1
Plch1

phospholipase C, eta 1

chr6_+_17636983 0.077 ENSMUST00000015877.7
Capza2
capping protein (actin filament) muscle Z-line, alpha 2
chr15_+_78913916 0.076 ENSMUST00000089378.4
Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr2_+_163694015 0.072 ENSMUST00000109400.2
Pkig
protein kinase inhibitor, gamma
chr14_+_4514758 0.072 ENSMUST00000112776.2
Gm3173
predicted gene 3173
chr8_+_85171322 0.070 ENSMUST00000076896.5
Gm6531
predicted gene 6531
chr14_-_6874257 0.066 ENSMUST00000178298.1
ENSMUST00000179374.1
Gm3667
Gm3629
predicted gene 3667
predicted gene 3629
chr12_-_73286698 0.065 ENSMUST00000116420.2
Trmt5
TRM5 tRNA methyltransferase 5
chr6_+_112273758 0.062 ENSMUST00000032376.5
Lmcd1
LIM and cysteine-rich domains 1
chr16_-_17722879 0.061 ENSMUST00000080936.6
ENSMUST00000012259.7
Med15

mediator complex subunit 15

chr11_-_97996171 0.061 ENSMUST00000042971.9
Arl5c
ADP-ribosylation factor-like 5C
chr3_-_151762906 0.060 ENSMUST00000046739.4
Ifi44l
interferon-induced protein 44 like
chr2_+_127587214 0.059 ENSMUST00000028852.6
Mrps5
mitochondrial ribosomal protein S5
chr11_-_97782409 0.058 ENSMUST00000103146.4
Rpl23
ribosomal protein L23
chr11_-_97782377 0.058 ENSMUST00000128801.1
Rpl23
ribosomal protein L23
chr18_-_40219324 0.056 ENSMUST00000025364.4
Yipf5
Yip1 domain family, member 5
chr14_-_5863663 0.056 ENSMUST00000178594.1
Gm8237
predicted gene 8237
chr11_-_101425330 0.051 ENSMUST00000103102.3
Ptges3l
prostaglandin E synthase 3 (cytosolic)-like
chr11_-_101417615 0.050 ENSMUST00000070395.8
Aarsd1
alanyl-tRNA synthetase domain containing 1
chr18_-_43477764 0.049 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr6_-_48708206 0.048 ENSMUST00000119315.1
ENSMUST00000053661.4
Gimap6

GTPase, IMAP family member 6

chr6_-_122340499 0.046 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr10_-_127522428 0.043 ENSMUST00000026470.4
Shmt2
serine hydroxymethyltransferase 2 (mitochondrial)
chr14_+_4198185 0.038 ENSMUST00000180184.1
Gm2974
predicted gene 2974
chr17_-_24443077 0.035 ENSMUST00000119932.1
Dnase1l2
deoxyribonuclease 1-like 2
chr14_+_3825596 0.035 ENSMUST00000178256.1
Gm3002
predicted gene 3002
chr16_+_10835046 0.034 ENSMUST00000037913.8
Rmi2
RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae)
chr14_+_4126066 0.033 ENSMUST00000167397.2
Gm8108
predicted gene 8108
chr14_+_58893465 0.032 ENSMUST00000079960.1
Rpl13-ps3
ribosomal protein L13, pseudogene 3
chr8_+_107436355 0.031 ENSMUST00000166615.1
Wwp2
WW domain containing E3 ubiquitin protein ligase 2
chr2_+_25403128 0.031 ENSMUST00000154809.1
ENSMUST00000055921.7
ENSMUST00000141567.1
Npdc1


neural proliferation, differentiation and control 1


chr14_+_4871156 0.026 ENSMUST00000166410.2
Gm3264
predicted gene 3264
chr14_+_3667518 0.021 ENSMUST00000112801.3
Gm3020
predicted gene 3020
chr4_+_8535604 0.021 ENSMUST00000060232.7
Rab2a
RAB2A, member RAS oncogene family
chr14_-_6266620 0.020 ENSMUST00000096172.5
Gm3411
predicted gene 3411
chr11_+_78188737 0.020 ENSMUST00000108322.2
Rab34
RAB34, member of RAS oncogene family
chr2_-_132111440 0.017 ENSMUST00000128899.1
Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
chr2_+_59612034 0.015 ENSMUST00000112568.1
ENSMUST00000037526.4
Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr3_-_107333289 0.011 ENSMUST00000061772.9
Rbm15
RNA binding motif protein 15
chr8_+_85492568 0.011 ENSMUST00000034136.5
Gpt2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chrX_+_36328353 0.010 ENSMUST00000016383.3
Lonrf3
LON peptidase N-terminal domain and ring finger 3
chr2_-_156180135 0.010 ENSMUST00000126992.1
ENSMUST00000146288.1
ENSMUST00000029149.6
ENSMUST00000109587.2
ENSMUST00000109584.1
Rbm39




RNA binding motif protein 39




chr2_+_155236529 0.008 ENSMUST00000109682.2
Dynlrb1
dynein light chain roadblock-type 1
chr9_+_108662098 0.004 ENSMUST00000035222.5
Slc25a20
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20
chr14_+_4430992 0.002 ENSMUST00000164603.1
ENSMUST00000166848.1
Gm3173

predicted gene 3173

chr2_+_155236602 0.001 ENSMUST00000150602.1
Dynlrb1
dynein light chain roadblock-type 1
chr11_+_73160403 0.001 ENSMUST00000006104.3
P2rx5
purinergic receptor P2X, ligand-gated ion channel, 5
chr4_+_127172866 0.000 ENSMUST00000106094.2
Dlgap3
discs, large (Drosophila) homolog-associated protein 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0072070 loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.3 0.9 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.2 0.6 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.4 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097) negative regulation of lymphocyte migration(GO:2000402)
0.1 0.4 GO:1902044 regulation of Fas signaling pathway(GO:1902044) negative regulation of Fas signaling pathway(GO:1902045)
0.1 0.5 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.4 GO:1903288 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.1 0.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.7 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 0.2 GO:0071544 diphosphoinositol polyphosphate metabolic process(GO:0071543) diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.1 0.4 GO:0032796 uropod organization(GO:0032796)
0.1 0.6 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.1 0.4 GO:0034227 tRNA thio-modification(GO:0034227)
0.1 0.8 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.3 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 1.0 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 0.2 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.5 GO:2000194 regulation of female gonad development(GO:2000194)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.3 GO:0043206 extracellular fibril organization(GO:0043206)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0032829 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) negative regulation of interleukin-2 biosynthetic process(GO:0045085) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.2 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.2 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.1 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.0 0.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.2 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.4 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.5 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.3 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.0 GO:0006545 glycine biosynthetic process(GO:0006545)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.1 GO:1990879 CST complex(GO:1990879)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.2 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.0 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.2 GO:0044453 nuclear membrane part(GO:0044453)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.0 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 0.4 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.7 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 0.1 GO:0043912 D-lysine oxidase activity(GO:0043912)
0.0 0.4 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.2 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 1.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.6 GO:0010181 FMN binding(GO:0010181)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0034916 4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.0 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)