Motif ID: Nfat5

Z-value: 0.790


Transcription factors associated with Nfat5:

Gene SymbolEntrez IDGene Name
Nfat5 ENSMUSG00000003847.10 Nfat5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfat5mm10_v2_chr8_+_107293463_1072934830.401.6e-01Click!


Activity profile for motif Nfat5.

activity profile for motif Nfat5


Sorted Z-values histogram for motif Nfat5

Sorted Z-values for motif Nfat5



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfat5

PNG image of the network

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Top targets:


Showing 1 to 20 of 88 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_144209558 2.442 ENSMUST00000111749.1
ENSMUST00000170367.2
Sox5

SRY-box containing gene 5

chr6_-_144209471 2.413 ENSMUST00000038815.7
Sox5
SRY-box containing gene 5
chr6_-_144209448 2.393 ENSMUST00000077160.5
Sox5
SRY-box containing gene 5
chr10_-_29535857 2.036 ENSMUST00000092623.3
Rspo3
R-spondin 3 homolog (Xenopus laevis)
chr2_+_172549581 1.514 ENSMUST00000030391.2
Tfap2c
transcription factor AP-2, gamma
chr10_-_95415484 1.272 ENSMUST00000172070.1
ENSMUST00000150432.1
Socs2

suppressor of cytokine signaling 2

chr4_-_82505749 1.128 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr10_-_95415283 1.121 ENSMUST00000119917.1
Socs2
suppressor of cytokine signaling 2
chr2_+_68117713 1.106 ENSMUST00000112346.2
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr4_-_82505707 1.019 ENSMUST00000107248.1
ENSMUST00000107247.1
Nfib

nuclear factor I/B

chr3_-_129755305 0.935 ENSMUST00000029653.2
Egf
epidermal growth factor
chr6_-_58907120 0.934 ENSMUST00000059539.3
Nap1l5
nucleosome assembly protein 1-like 5
chr5_-_124354671 0.618 ENSMUST00000031341.4
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr13_+_44840686 0.598 ENSMUST00000173906.1
Jarid2
jumonji, AT rich interactive domain 2
chr6_-_101377897 0.588 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr8_+_86745679 0.567 ENSMUST00000098532.2
Gm10638
predicted gene 10638
chr5_-_66618772 0.560 ENSMUST00000162994.1
ENSMUST00000159512.1
ENSMUST00000159786.1
Apbb2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr15_-_38078842 0.501 ENSMUST00000110336.2
Ubr5
ubiquitin protein ligase E3 component n-recognin 5
chr16_-_55838827 0.460 ENSMUST00000096026.2
ENSMUST00000036273.6
ENSMUST00000114457.1
Nfkbiz


nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta


chr9_-_13446753 0.448 ENSMUST00000167906.2
Gm17571
predicted gene, 17571

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 7.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 2.4 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.5 2.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 2.0 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.5 1.5 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.1 1.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.2 0.9 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.1 0.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.6 GO:0007528 neuromuscular junction development(GO:0007528)
0.2 0.5 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.5 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 0.3 GO:1900044 regulation of protein K63-linked ubiquitination(GO:1900044)
0.1 0.3 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.3 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.1 0.3 GO:0019659 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0 0.3 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.3 GO:0042447 hormone catabolic process(GO:0042447)
0.0 0.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)

Gene overrepresentation in cellular_component category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.2 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.1 2.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0044327 dendritic spine membrane(GO:0032591) dendritic spine head(GO:0044327)
0.0 0.1 GO:0034464 BBSome(GO:0034464)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.0 GO:0046982 protein heterodimerization activity(GO:0046982)
0.5 2.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 2.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 2.0 GO:0005109 frizzled binding(GO:0005109)
0.0 1.5 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 1.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.6 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.3 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.3 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.3 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.1 0.3 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 0.3 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.0 0.3 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)