Motif ID: Nfatc1

Z-value: 7.472


Transcription factors associated with Nfatc1:

Gene SymbolEntrez IDGene Name
Nfatc1 ENSMUSG00000033016.9 Nfatc1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfatc1mm10_v2_chr18_-_80708115_807081800.535.3e-02Click!


Activity profile for motif Nfatc1.

activity profile for motif Nfatc1


Sorted Z-values histogram for motif Nfatc1

Sorted Z-values for motif Nfatc1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfatc1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 198 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_3000922 134.384 ENSMUST00000151376.2
 Gm10722
predicted gene 10722
chr9_+_3027439 132.266 ENSMUST00000177875.1
ENSMUST00000179982.1
 Gm10717

predicted gene 10717

chr9_+_3013140 118.656 ENSMUST00000143083.2
 Gm10721
predicted gene 10721
chr9_+_3023547 109.818 ENSMUST00000099046.3
 Gm10718
predicted gene 10718
chr9_+_3004457 108.000 ENSMUST00000178348.1
 Gm11168
predicted gene 11168
chr9_+_3037111 103.900 ENSMUST00000177969.1
 Gm10715
predicted gene 10715
chr9_+_3036877 93.794 ENSMUST00000155807.2
 Gm10715
predicted gene 10715
chr9_+_3025417 93.504 ENSMUST00000075573.6
 Gm10717
predicted gene 10717
chr9_+_3017408 92.252 ENSMUST00000099049.3
 Gm10719
predicted gene 10719
chr9_+_3034599 87.459 ENSMUST00000178641.1
 Gm17535
predicted gene, 17535
chr2_-_98667264 85.285 ENSMUST00000099683.1
 Gm10800
predicted gene 10800
chr9_+_3005125 84.559 ENSMUST00000179881.1
 Gm11168
predicted gene 11168
chr14_-_19418930 77.852 ENSMUST00000177817.1
 Gm21738
predicted gene, 21738
chr9_+_3015654 76.211 ENSMUST00000099050.3
 Gm10720
predicted gene 10720
chr2_+_98662227 66.543 ENSMUST00000099684.3
 Gm10801
predicted gene 10801
chr9_+_3018753 62.277 ENSMUST00000179272.1
 Gm10719
predicted gene 10719
chr6_+_15185203 7.965 ENSMUST00000154448.1
 Foxp2
forkhead box P2
chr12_+_75308308 6.163 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
 Rhoj


ras homolog gene family, member J


chr18_+_20665250 5.903 ENSMUST00000075312.3
 Ttr
transthyretin
chr2_-_113758638 5.668 ENSMUST00000099575.3
 Grem1
gremlin 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 762.8 GO:0008150 biological_process(GO:0008150)
0.7 8.0 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.4 6.9 GO:0032060 bleb assembly(GO:0032060)
2.1 6.3 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
1.2 5.9 GO:0070327 thyroid hormone transport(GO:0070327)
0.8 5.4 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
1.0 4.8 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.2 4.6 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.4 4.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 4.3 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.7 4.2 GO:0035989 tendon development(GO:0035989)
0.4 3.1 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.5 3.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.3 2.7 GO:0042118 endothelial cell activation(GO:0042118)
0.1 2.6 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.4 2.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.7 2.2 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
0.7 2.2 GO:0043379 memory T cell differentiation(GO:0043379)
0.3 2.2 GO:0032808 lacrimal gland development(GO:0032808)
0.7 2.1 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 841.1 GO:0005575 cellular_component(GO:0005575)
0.3 6.3 GO:0043218 compact myelin(GO:0043218)
0.2 4.8 GO:0005605 basal lamina(GO:0005605)
0.3 4.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.8 3.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 2.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.3 2.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 2.2 GO:0002080 acrosomal membrane(GO:0002080)
0.1 1.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.5 1.4 GO:0000811 GINS complex(GO:0000811)
0.1 1.3 GO:0097449 astrocyte projection(GO:0097449)
0.2 1.1 GO:0002177 manchette(GO:0002177)
0.2 1.1 GO:0042629 mast cell granule(GO:0042629)
0.2 0.8 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.4 GO:0018444 translation release factor complex(GO:0018444)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 803.6 GO:0003674 molecular_function(GO:0003674)
0.9 7.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.6 5.7 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.6 5.4 GO:0038191 neuropilin binding(GO:0038191)
0.6 4.6 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 4.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.8 3.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.6 3.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.7 2.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 2.6 GO:0042287 MHC protein binding(GO:0042287)
0.2 2.5 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 2.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.2 2.2 GO:0003680 AT DNA binding(GO:0003680)
0.1 2.2 GO:0001848 complement binding(GO:0001848)
0.0 2.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 2.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 2.0 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 1.6 GO:0015288 porin activity(GO:0015288)
0.1 1.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.5 1.4 GO:0004994 somatostatin receptor activity(GO:0004994)