Motif ID: Nfatc2

Z-value: 1.921


Transcription factors associated with Nfatc2:

Gene SymbolEntrez IDGene Name
Nfatc2 ENSMUSG00000027544.10 Nfatc2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfatc2mm10_v2_chr2_-_168601620_1686016570.165.7e-01Click!


Activity profile for motif Nfatc2.

activity profile for motif Nfatc2


Sorted Z-values histogram for motif Nfatc2

Sorted Z-values for motif Nfatc2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfatc2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_61185558 14.053 ENSMUST00000166381.1
 Cdr1
cerebellar degeneration related antigen 1
chr9_+_3000922 8.192 ENSMUST00000151376.2
 Gm10722
predicted gene 10722
chr9_+_3027439 7.404 ENSMUST00000177875.1
ENSMUST00000179982.1
 Gm10717

predicted gene 10717

chr9_+_3004457 7.260 ENSMUST00000178348.1
 Gm11168
predicted gene 11168
chr9_+_3013140 6.876 ENSMUST00000143083.2
 Gm10721
predicted gene 10721
chr9_+_3023547 6.841 ENSMUST00000099046.3
 Gm10718
predicted gene 10718
chr9_+_3017408 6.556 ENSMUST00000099049.3
 Gm10719
predicted gene 10719
chr9_+_3037111 6.479 ENSMUST00000177969.1
 Gm10715
predicted gene 10715
chr9_+_3034599 6.378 ENSMUST00000178641.1
 Gm17535
predicted gene, 17535
chr9_+_3005125 6.256 ENSMUST00000179881.1
 Gm11168
predicted gene 11168
chr2_+_98662227 6.063 ENSMUST00000099684.3
 Gm10801
predicted gene 10801
chr9_+_3036877 6.004 ENSMUST00000155807.2
 Gm10715
predicted gene 10715
chr2_-_98667264 6.004 ENSMUST00000099683.1
 Gm10800
predicted gene 10800
chr9_+_3015654 5.703 ENSMUST00000099050.3
 Gm10720
predicted gene 10720
chr9_+_3025417 5.576 ENSMUST00000075573.6
 Gm10717
predicted gene 10717
chr14_-_19418930 4.989 ENSMUST00000177817.1
 Gm21738
predicted gene, 21738
chr9_+_3018753 4.821 ENSMUST00000179272.1
 Gm10719
predicted gene 10719
chr6_-_59024340 3.406 ENSMUST00000173193.1
 Fam13a
family with sequence similarity 13, member A
chr6_-_144209471 3.112 ENSMUST00000038815.7
 Sox5
SRY-box containing gene 5
chr15_-_12592556 2.907 ENSMUST00000075317.5
 Pdzd2
PDZ domain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 267 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 8.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.4 3.1 GO:0044337 canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.3 3.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
1.0 3.0 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.6 2.8 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.1 2.6 GO:0021860 pyramidal neuron development(GO:0021860)
0.8 2.5 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.6 2.4 GO:0051866 general adaptation syndrome(GO:0051866)
0.6 2.4 GO:0035063 nuclear speck organization(GO:0035063)
0.6 2.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 2.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.4 2.1 GO:0015671 oxygen transport(GO:0015671)
0.3 1.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 1.8 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.2 1.8 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 1.8 GO:0010669 epithelial structure maintenance(GO:0010669)
0.2 1.7 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.5 1.6 GO:1901731 calcium-mediated signaling using extracellular calcium source(GO:0035585) positive regulation of platelet aggregation(GO:1901731)
0.2 1.6 GO:0098907 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.1 1.6 GO:0016180 snRNA processing(GO:0016180)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 103 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.3 GO:0060076 excitatory synapse(GO:0060076)
0.1 8.8 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.2 5.8 GO:0043034 costamere(GO:0043034)
0.1 3.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 3.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 3.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 3.0 GO:0016234 inclusion body(GO:0016234)
0.9 2.8 GO:0043512 inhibin A complex(GO:0043512)
0.0 2.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.2 GO:0055037 recycling endosome(GO:0055037)
0.3 2.1 GO:0005833 hemoglobin complex(GO:0005833)
0.1 2.1 GO:0071565 nBAF complex(GO:0071565)
0.1 2.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 1.7 GO:0097433 dense body(GO:0097433)
0.0 1.7 GO:0030426 growth cone(GO:0030426)
0.4 1.6 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 1.6 GO:0032039 integrator complex(GO:0032039)
0.1 1.6 GO:0043194 axon initial segment(GO:0043194)
0.1 1.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.4 GO:0035098 ESC/E(Z) complex(GO:0035098)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 176 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 3.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 3.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 3.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 3.2 GO:0008017 microtubule binding(GO:0008017)
0.5 3.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.4 3.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 2.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 2.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.5 2.1 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.1 2.1 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.1 2.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 2.0 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.3 1.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 1.8 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.7 GO:0051018 protein kinase A binding(GO:0051018)
0.1 1.6 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 1.6 GO:0051010 microtubule plus-end binding(GO:0051010)