Motif ID: Nfatc3
Z-value: 2.381
Transcription factors associated with Nfatc3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Nfatc3 | ENSMUSG00000031902.9 | Nfatc3 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Nfatc3 | mm10_v2_chr8_+_106059562_106059623 | -0.36 | 2.1e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 145 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.7 | 8.0 | GO:0002302 | CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) |
| 1.0 | 7.0 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
| 0.6 | 6.9 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.4 | 5.5 | GO:0060159 | regulation of dopamine receptor signaling pathway(GO:0060159) |
| 0.1 | 3.5 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.0 | 3.1 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.7 | 3.0 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
| 0.5 | 3.0 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
| 1.0 | 2.9 | GO:0060854 | patterning of lymph vessels(GO:0060854) |
| 0.9 | 2.8 | GO:0003278 | apoptotic process involved in heart morphogenesis(GO:0003278) |
| 0.7 | 2.8 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) positive regulation of isotype switching to IgG isotypes(GO:0048304) |
| 0.4 | 2.7 | GO:0072539 | T-helper 17 cell differentiation(GO:0072539) |
| 0.7 | 2.6 | GO:0060745 | mammary gland branching involved in pregnancy(GO:0060745) |
| 0.4 | 2.2 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
| 0.4 | 2.1 | GO:0021730 | trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) |
| 0.2 | 2.1 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
| 0.1 | 2.0 | GO:0050819 | negative regulation of coagulation(GO:0050819) |
| 0.0 | 2.0 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.2 | 1.8 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
| 0.3 | 1.7 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 65 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.9 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.1 | 5.8 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.5 | 4.1 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.1 | 3.2 | GO:0016459 | myosin complex(GO:0016459) |
| 0.1 | 2.6 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.1 | 2.5 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.0 | 2.3 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 2.2 | GO:0032432 | actin filament bundle(GO:0032432) |
| 0.1 | 2.0 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 1.9 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.1 | 1.8 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.0 | 1.7 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.1 | 1.5 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.0 | 1.5 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 1.5 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.2 | 1.4 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 0.2 | 1.4 | GO:0030478 | actin cap(GO:0030478) |
| 0.0 | 1.4 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.0 | 1.3 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 1.2 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 120 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.5 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 7.3 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.2 | 7.2 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.6 | 3.0 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.0 | 3.0 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.3 | 2.9 | GO:0001224 | RNA polymerase II transcription cofactor binding(GO:0001224) |
| 0.0 | 2.9 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.6 | 2.8 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.9 | 2.6 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
| 0.0 | 2.6 | GO:0035326 | enhancer binding(GO:0035326) |
| 0.0 | 2.6 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
| 0.0 | 2.5 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.6 | 2.4 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.1 | 2.3 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.1 | 2.2 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
| 0.1 | 2.2 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.0 | 2.1 | GO:0002020 | protease binding(GO:0002020) |
| 0.0 | 2.0 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.4 | 1.9 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.1 | 1.9 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
