Motif ID: Nfatc4

Z-value: 0.625


Transcription factors associated with Nfatc4:

Gene SymbolEntrez IDGene Name
Nfatc4 ENSMUSG00000023411.5 Nfatc4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfatc4mm10_v2_chr14_+_55824795_55824889-0.621.8e-02Click!


Activity profile for motif Nfatc4.

activity profile for motif Nfatc4


Sorted Z-values histogram for motif Nfatc4

Sorted Z-values for motif Nfatc4



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfatc4

PNG image of the network

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Top targets:


Showing 1 to 20 of 62 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_91400990 1.170 ENSMUST00000021346.7
ENSMUST00000021343.6
 Tshr

thyroid stimulating hormone receptor

chr2_+_125136692 1.036 ENSMUST00000099452.2
 Ctxn2
cortexin 2
chr3_+_84925476 0.996 ENSMUST00000107675.1
 Fbxw7
F-box and WD-40 domain protein 7
chr16_+_43364145 0.882 ENSMUST00000148775.1
 Zbtb20
zinc finger and BTB domain containing 20
chr10_+_21993890 0.868 ENSMUST00000092673.4
 Sgk1
serum/glucocorticoid regulated kinase 1
chr1_-_56978534 0.847 ENSMUST00000177282.1
 Satb2
special AT-rich sequence binding protein 2
chr15_+_3270767 0.827 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr14_-_25927672 0.824 ENSMUST00000185006.1
 Tmem254a
transmembrane protein 254a
chr2_+_116067213 0.815 ENSMUST00000152412.1
 G630016G05Rik
RIKEN cDNA G630016G05 gene
chr14_-_25927250 0.801 ENSMUST00000100811.5
 Tmem254a
transmembrane protein 254a
chr14_-_26067355 0.787 ENSMUST00000100819.5
 Tmem254c
transmembrane protein 254c
chr17_-_49564262 0.748 ENSMUST00000057610.6
 Daam2
dishevelled associated activator of morphogenesis 2
chr18_-_15063560 0.667 ENSMUST00000168989.1
 Kctd1
potassium channel tetramerisation domain containing 1
chr18_+_73863672 0.600 ENSMUST00000134847.1
 Mro
maestro
chr5_+_145114280 0.585 ENSMUST00000141602.1
 Arpc1b
actin related protein 2/3 complex, subunit 1B
chr3_-_152193803 0.572 ENSMUST00000050073.6
 Dnajb4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr1_-_144177259 0.545 ENSMUST00000111941.1
ENSMUST00000052375.1
 Rgs13

regulator of G-protein signaling 13

chr2_-_116067391 0.507 ENSMUST00000140185.1
 2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr1_-_56969864 0.471 ENSMUST00000177424.1
 Satb2
special AT-rich sequence binding protein 2
chr16_-_59555752 0.463 ENSMUST00000179383.1
ENSMUST00000044604.8
 Crybg3

beta-gamma crystallin domain containing 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 1.2 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.2 1.0 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.9 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.8 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.5 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.1 0.4 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
0.1 0.4 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.1 0.3 GO:0003032 detection of oxygen(GO:0003032) regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905005)
0.0 0.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013) positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)

Gene overrepresentation in cellular_component category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 1.0 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)

Gene overrepresentation in molecular_function category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.2 1.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.9 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.8 GO:0008430 selenium binding(GO:0008430)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)