Motif ID: Nfe2_Bach1_Mafk

Z-value: 1.076

Transcription factors associated with Nfe2_Bach1_Mafk:

Gene SymbolEntrez IDGene Name
Bach1 ENSMUSG00000025612.5 Bach1
Mafk ENSMUSG00000018143.4 Mafk
Nfe2 ENSMUSG00000058794.6 Nfe2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bach1mm10_v2_chr16_+_87698904_87698959-0.497.6e-02Click!
Nfe2mm10_v2_chr15_-_103251465_103251705-0.263.7e-01Click!
Mafkmm10_v2_chr5_+_139791513_139791539-0.117.1e-01Click!


Activity profile for motif Nfe2_Bach1_Mafk.

activity profile for motif Nfe2_Bach1_Mafk


Sorted Z-values histogram for motif Nfe2_Bach1_Mafk

Sorted Z-values for motif Nfe2_Bach1_Mafk



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfe2_Bach1_Mafk

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_165769392 2.159 ENSMUST00000040298.4
 Creg1
cellular repressor of E1A-stimulated genes 1
chr4_-_136886187 2.144 ENSMUST00000046384.8
 C1qb
complement component 1, q subcomponent, beta polypeptide
chr6_+_17463927 1.932 ENSMUST00000115442.1
 Met
met proto-oncogene
chr4_+_116685859 1.748 ENSMUST00000129315.1
ENSMUST00000106470.1
 Prdx1

peroxiredoxin 1

chr18_+_61639542 1.623 ENSMUST00000183083.1
ENSMUST00000183087.1
 Gm20748

predicted gene, 20748

chr19_-_12501996 1.519 ENSMUST00000045521.7
 Dtx4
deltex 4 homolog (Drosophila)
chr4_+_116685544 1.509 ENSMUST00000135573.1
ENSMUST00000151129.1
 Prdx1

peroxiredoxin 1

chr3_-_116968827 1.495 ENSMUST00000119557.1
 Palmd
palmdelphin
chr7_-_110862944 1.424 ENSMUST00000033050.3
 Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr13_-_113663670 1.393 ENSMUST00000054650.4
 Hspb3
heat shock protein 3
chr6_+_17463749 1.365 ENSMUST00000115443.1
 Met
met proto-oncogene
chr5_-_108675569 1.253 ENSMUST00000051757.7
 Slc26a1
solute carrier family 26 (sulfate transporter), member 1
chr6_+_38918969 1.228 ENSMUST00000003017.6
 Tbxas1
thromboxane A synthase 1, platelet
chr7_+_139834148 1.174 ENSMUST00000026548.7
 Gpr123
G protein-coupled receptor 123
chr6_+_17463826 1.119 ENSMUST00000140070.1
 Met
met proto-oncogene
chr7_+_110774240 1.108 ENSMUST00000147587.1
 Ampd3
adenosine monophosphate deaminase 3
chr6_-_129533267 1.082 ENSMUST00000181594.1
 1700101I11Rik
RIKEN cDNA 1700101I11 gene
chr2_+_25395866 1.002 ENSMUST00000028328.2
 Entpd2
ectonucleoside triphosphate diphosphohydrolase 2
chr18_+_73863672 0.977 ENSMUST00000134847.1
 Mro
maestro
chr14_-_79301623 0.959 ENSMUST00000022595.7
 Rgcc
regulator of cell cycle

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 92 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 5.3 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2 4.2 GO:0019430 removal of superoxide radicals(GO:0019430)
0.1 2.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 1.9 GO:0032264 IMP salvage(GO:0032264)
0.4 1.8 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.2 1.6 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.2 1.3 GO:0019532 oxalate transport(GO:0019532)
0.1 1.3 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.2 1.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 1.2 GO:0010819 regulation of T cell chemotaxis(GO:0010819)
0.0 1.1 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.3 1.0 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.1 1.0 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 1.0 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 0.9 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.0 0.9 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.9 GO:0030641 regulation of cellular pH(GO:0030641)
0.1 0.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.7 GO:0015862 uridine transport(GO:0015862)
0.2 0.6 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.8 GO:0009925 basal plasma membrane(GO:0009925)
0.1 3.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 2.0 GO:0000502 proteasome complex(GO:0000502)
0.0 1.8 GO:0005581 collagen trimer(GO:0005581)
0.0 1.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 1.0 GO:0005605 basal lamina(GO:0005605)
0.3 0.9 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.9 GO:0031519 PcG protein complex(GO:0031519)
0.1 0.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.8 GO:0032420 stereocilium(GO:0032420)
0.1 0.7 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.7 GO:0005838 proteasome regulatory particle(GO:0005838)
0.2 0.6 GO:0036501 UFD1-NPL4 complex(GO:0036501)
0.1 0.6 GO:1990462 omegasome(GO:1990462)
0.1 0.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.6 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.6 GO:0031045 dense core granule(GO:0031045)
0.0 0.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.2 0.5 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 4.4 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.3 3.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 2.2 GO:0010181 FMN binding(GO:0010181)
0.3 1.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.5 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.1 1.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 1.0 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 1.0 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.2 0.9 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.9 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.9 GO:0045296 cadherin binding(GO:0045296)
0.0 0.9 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.9 GO:0005518 collagen binding(GO:0005518)
0.1 0.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.7 GO:0032050 clathrin heavy chain binding(GO:0032050)