Motif ID: Nfe2l1_Mafg

Z-value: 1.367

Transcription factors associated with Nfe2l1_Mafg:

Gene SymbolEntrez IDGene Name
Mafg ENSMUSG00000051510.7 Mafg
Mafg ENSMUSG00000053906.4 Mafg
Nfe2l1 ENSMUSG00000038615.11 Nfe2l1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfe2l1mm10_v2_chr11_-_96829483_968295020.687.0e-03Click!
Mafgmm10_v2_chr11_-_120633594_120633605-0.621.8e-02Click!


Activity profile for motif Nfe2l1_Mafg.

activity profile for motif Nfe2l1_Mafg


Sorted Z-values histogram for motif Nfe2l1_Mafg

Sorted Z-values for motif Nfe2l1_Mafg



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfe2l1_Mafg

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_64090265 3.833 ENSMUST00000105439.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr9_-_66795331 3.403 ENSMUST00000113730.2
 Aph1b
anterior pharynx defective 1b homolog (C. elegans)
chr7_-_130266191 2.926 ENSMUST00000122054.1
 Fgfr2
fibroblast growth factor receptor 2
chr6_-_99044414 2.919 ENSMUST00000177507.1
ENSMUST00000123992.1
 Foxp1

forkhead box P1

chr19_+_56722372 2.909 ENSMUST00000038949.4
 Adrb1
adrenergic receptor, beta 1
chr7_+_87803815 2.779 ENSMUST00000125009.1
ENSMUST00000155358.1
 Grm5

glutamate receptor, metabotropic 5

chr7_-_130266237 2.516 ENSMUST00000117872.1
ENSMUST00000120187.1
 Fgfr2

fibroblast growth factor receptor 2

chr9_-_66795469 2.513 ENSMUST00000034934.8
 Aph1b
anterior pharynx defective 1b homolog (C. elegans)
chr6_+_88724667 2.505 ENSMUST00000163271.1
 Mgll
monoglyceride lipase
chr10_-_13868779 2.498 ENSMUST00000105534.3
 Aig1
androgen-induced 1
chr5_+_35056813 2.400 ENSMUST00000101298.2
ENSMUST00000114270.1
ENSMUST00000133381.1
 Dok7


docking protein 7


chr6_+_88724828 2.357 ENSMUST00000089449.2
 Mgll
monoglyceride lipase
chr4_+_101507855 2.304 ENSMUST00000038207.5
 Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr9_-_66834648 2.265 ENSMUST00000057261.8
ENSMUST00000169282.1
 Aph1c

anterior pharynx defective 1c homolog (C. elegans)

chr2_-_65022740 2.028 ENSMUST00000028252.7
 Grb14
growth factor receptor bound protein 14
chr6_-_23248264 2.028 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr14_+_74640840 2.028 ENSMUST00000036653.3
 Htr2a
5-hydroxytryptamine (serotonin) receptor 2A
chr12_-_54986363 2.000 ENSMUST00000173433.1
ENSMUST00000173803.1
 Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr18_-_62741387 1.946 ENSMUST00000097557.3
 Spink13
serine peptidase inhibitor, Kazal type 13
chr4_+_102570065 1.791 ENSMUST00000097950.2
 Pde4b
phosphodiesterase 4B, cAMP specific

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 92 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.9 GO:0007219 Notch signaling pathway(GO:0007219)
1.8 5.4 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) coronal suture morphogenesis(GO:0060365) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.7 4.9 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 4.0 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.3 3.8 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
1.0 2.9 GO:1900133 renin secretion into blood stream(GO:0002001) negative regulation of urine volume(GO:0035811) regulation of renin secretion into blood stream(GO:1900133)
0.4 2.9 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.3 2.8 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 2.6 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 2.5 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.4 2.3 GO:0072318 clathrin coat disassembly(GO:0072318)
0.7 2.0 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.3 2.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 2.0 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 2.0 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.4 1.9 GO:0060467 negative regulation of fertilization(GO:0060467)
0.2 1.9 GO:0071225 cellular response to muramyl dipeptide(GO:0071225)
0.1 1.8 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 1.6 GO:0001696 gastric acid secretion(GO:0001696)
0.1 1.6 GO:2001224 positive regulation of neuron migration(GO:2001224)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 6.0 GO:0005938 cell cortex(GO:0005938)
0.3 4.9 GO:0043196 varicosity(GO:0043196)
0.1 3.3 GO:1990391 DNA repair complex(GO:1990391)
0.2 2.8 GO:0097449 astrocyte projection(GO:0097449)
0.0 2.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 2.2 GO:0031594 neuromuscular junction(GO:0031594)
0.4 2.0 GO:0008623 CHRAC(GO:0008623)
0.2 2.0 GO:0070852 cell body fiber(GO:0070852)
0.0 2.0 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 1.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.6 GO:0030424 axon(GO:0030424)
0.0 1.5 GO:0005776 autophagosome(GO:0005776)
0.1 1.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.4 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 1.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.0 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.0 GO:0004175 endopeptidase activity(GO:0004175)
0.6 5.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 5.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.4 4.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 4.8 GO:0005158 insulin receptor binding(GO:0005158)
0.1 3.3 GO:0042162 telomeric DNA binding(GO:0042162)
1.0 2.9 GO:0051379 epinephrine binding(GO:0051379)
0.9 2.8 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.0 2.8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 2.8 GO:0005096 GTPase activator activity(GO:0005096)
0.1 2.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.2 2.3 GO:0015197 peptide transporter activity(GO:0015197)
0.0 2.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 2.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.5 2.0 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589)
0.1 2.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 1.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.8 GO:0030552 cAMP binding(GO:0030552)
0.5 1.6 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)