Motif ID: Nfia

Z-value: 1.376


Transcription factors associated with Nfia:

Gene SymbolEntrez IDGene Name
Nfia ENSMUSG00000028565.12 Nfia

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfiamm10_v2_chr4_+_97772734_97772848-0.641.5e-02Click!


Activity profile for motif Nfia.

activity profile for motif Nfia


Sorted Z-values histogram for motif Nfia

Sorted Z-values for motif Nfia



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfia

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_20665250 9.529 ENSMUST00000075312.3
 Ttr
transthyretin
chr6_+_141524379 4.399 ENSMUST00000032362.9
 Slco1c1
solute carrier organic anion transporter family, member 1c1
chr2_-_25470031 3.701 ENSMUST00000114251.1
 Ptgds
prostaglandin D2 synthase (brain)
chr11_-_102897123 3.603 ENSMUST00000067444.3
 Gfap
glial fibrillary acidic protein
chr2_-_25469742 3.535 ENSMUST00000114259.2
ENSMUST00000015234.6
 Ptgds

prostaglandin D2 synthase (brain)

chr11_-_102897146 3.033 ENSMUST00000077902.4
 Gfap
glial fibrillary acidic protein
chr11_+_78324200 2.482 ENSMUST00000102478.3
 Aldoc
aldolase C, fructose-bisphosphate
chr7_-_97417730 2.390 ENSMUST00000043077.7
 Thrsp
thyroid hormone responsive
chr8_+_65967157 2.319 ENSMUST00000072482.6
 March1
membrane-associated ring finger (C3HC4) 1
chr16_+_91269759 2.309 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr2_+_122147680 2.218 ENSMUST00000102476.4
 B2m
beta-2 microglobulin
chr7_+_130936172 2.197 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr1_+_167618246 2.103 ENSMUST00000111380.1
 Rxrg
retinoid X receptor gamma
chr6_+_125552948 1.942 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
 Vwf


Von Willebrand factor homolog


chr2_-_77703252 1.932 ENSMUST00000171063.1
 Zfp385b
zinc finger protein 385B
chr4_+_109978004 1.917 ENSMUST00000061187.3
 Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr4_-_136898803 1.883 ENSMUST00000046285.5
 C1qa
complement component 1, q subcomponent, alpha polypeptide
chr13_+_94173992 1.775 ENSMUST00000121618.1
 Lhfpl2
lipoma HMGIC fusion partner-like 2
chr3_+_90537306 1.707 ENSMUST00000107335.1
 S100a16
S100 calcium binding protein A16
chr2_+_32646586 1.700 ENSMUST00000009705.7
ENSMUST00000167841.1
 Eng

endoglin


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 351 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.9 9.6 GO:0070327 thyroid hormone transport(GO:0070327)
1.4 7.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
1.1 6.6 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.5 4.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 2.7 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 2.7 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.4 2.6 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.8 2.5 GO:0072180 mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180)
0.2 2.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 2.3 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.4 2.2 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.4 2.2 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.2 2.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 2.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 2.2 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 1.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 1.9 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.1 1.9 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.2 1.8 GO:0071285 cellular response to lithium ion(GO:0071285)
0.6 1.7 GO:0003032 detection of oxygen(GO:0003032)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 127 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.2 GO:0005615 extracellular space(GO:0005615)
0.0 8.8 GO:0005667 transcription factor complex(GO:0005667)
1.7 6.6 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 6.0 GO:0031012 extracellular matrix(GO:0031012)
0.1 5.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 3.7 GO:0005581 collagen trimer(GO:0005581)
0.0 3.0 GO:0005604 basement membrane(GO:0005604)
0.0 3.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.3 2.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 2.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.1 GO:0000786 nucleosome(GO:0000786)
0.4 2.0 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 1.9 GO:0005902 microvillus(GO:0005902)
0.2 1.7 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.7 GO:0043218 compact myelin(GO:0043218)
0.1 1.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.5 1.6 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 1.6 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.5 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 1.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 226 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 9.6 GO:0070324 thyroid hormone binding(GO:0070324)
1.8 7.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 5.8 GO:0005178 integrin binding(GO:0005178)
0.0 4.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 4.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
1.1 4.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 3.2 GO:0070412 R-SMAD binding(GO:0070412)
0.1 2.9 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.3 2.6 GO:0050693 LBD domain binding(GO:0050693)
0.4 2.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 2.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.3 GO:0042287 MHC protein binding(GO:0042287)
0.2 2.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 2.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 2.1 GO:0019003 GDP binding(GO:0019003)
0.2 1.9 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 1.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.6 1.7 GO:0005534 galactose binding(GO:0005534)
0.6 1.7 GO:0098809 nitrite reductase activity(GO:0098809)
0.2 1.7 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)