Motif ID: Nfic_Nfib

Z-value: 2.029

Transcription factors associated with Nfic_Nfib:

Gene SymbolEntrez IDGene Name
Nfib ENSMUSG00000008575.11 Nfib
Nfic ENSMUSG00000055053.11 Nfic

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfibmm10_v2_chr4_-_82705735_82705754-0.678.5e-03Click!
Nficmm10_v2_chr10_-_81427114_814271870.322.6e-01Click!


Activity profile for motif Nfic_Nfib.

activity profile for motif Nfic_Nfib


Sorted Z-values histogram for motif Nfic_Nfib

Sorted Z-values for motif Nfic_Nfib



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfic_Nfib

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_25470031 14.524 ENSMUST00000114251.1
 Ptgds
prostaglandin D2 synthase (brain)
chr2_-_25469742 13.168 ENSMUST00000114259.2
ENSMUST00000015234.6
 Ptgds

prostaglandin D2 synthase (brain)

chr1_+_43730593 7.250 ENSMUST00000027217.8
 1500015O10Rik
RIKEN cDNA 1500015O10 gene
chr2_+_32646586 5.914 ENSMUST00000009705.7
ENSMUST00000167841.1
 Eng

endoglin

chr11_+_78324200 4.865 ENSMUST00000102478.3
 Aldoc
aldolase C, fructose-bisphosphate
chr7_+_45017953 4.751 ENSMUST00000044111.7
 Rras
Harvey rat sarcoma oncogene, subgroup R
chr10_+_57784859 4.658 ENSMUST00000020024.5
 Fabp7
fatty acid binding protein 7, brain
chr3_+_94933041 4.386 ENSMUST00000090839.5
 Selenbp1
selenium binding protein 1
chr11_-_78984831 3.990 ENSMUST00000073001.4
ENSMUST00000108269.3
 Lgals9

lectin, galactose binding, soluble 9

chr11_-_77894096 3.485 ENSMUST00000017597.4
 Pipox
pipecolic acid oxidase
chr11_+_109485606 3.237 ENSMUST00000106697.1
 Arsg
arylsulfatase G
chr3_+_94693556 3.230 ENSMUST00000090848.3
ENSMUST00000173981.1
ENSMUST00000173849.1
ENSMUST00000174223.1
 Selenbp2



selenium binding protein 2



chr7_-_97417730 3.115 ENSMUST00000043077.7
 Thrsp
thyroid hormone responsive
chr18_-_80986578 3.063 ENSMUST00000057950.7
 Sall3
sal-like 3 (Drosophila)
chr2_+_76650264 2.985 ENSMUST00000099986.2
 Dfnb59
deafness, autosomal recessive 59 (human)
chr19_+_24673998 2.962 ENSMUST00000057243.4
 Tmem252
transmembrane protein 252
chr10_+_57784914 2.752 ENSMUST00000165013.1
 Fabp7
fatty acid binding protein 7, brain
chr11_-_78984946 2.620 ENSMUST00000108268.3
 Lgals9
lectin, galactose binding, soluble 9
chr1_-_191183244 2.472 ENSMUST00000027941.8
 Atf3
activating transcription factor 3
chr11_+_61485431 2.456 ENSMUST00000064783.3
ENSMUST00000040522.6
 Mfap4

microfibrillar-associated protein 4


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 180 entries
Log-likelihood per target Total log-likelihoodTermDescription
5.5 27.7 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.4 7.4 GO:0060134 prepulse inhibition(GO:0060134)
0.9 7.3 GO:0070314 G1 to G0 transition(GO:0070314)
0.9 6.9 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
2.2 6.6 GO:2000562 negative regulation of interferon-gamma secretion(GO:1902714) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.6 6.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
2.0 5.9 GO:0003032 detection of oxygen(GO:0003032)
0.5 5.7 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 5.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 4.6 GO:0060325 face morphogenesis(GO:0060325)
0.7 4.1 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
1.2 3.5 GO:0006553 lysine metabolic process(GO:0006553)
0.3 3.4 GO:0046415 urate metabolic process(GO:0046415)
0.2 3.1 GO:0021891 olfactory bulb interneuron development(GO:0021891)
1.0 2.9 GO:0048014 Tie signaling pathway(GO:0048014)
0.9 2.8 GO:0072180 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180)
0.1 2.8 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.2 2.7 GO:0030574 collagen catabolic process(GO:0030574)
0.0 2.7 GO:0048747 muscle fiber development(GO:0048747)
0.2 2.6 GO:1903672 positive regulation of sprouting angiogenesis(GO:1903672)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 91 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 27.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 8.8 GO:0043025 neuronal cell body(GO:0043025)
0.0 8.5 GO:0005730 nucleolus(GO:0005730)
0.0 6.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
1.9 5.6 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.1 5.2 GO:0005844 polysome(GO:0005844)
0.1 5.1 GO:0072562 blood microparticle(GO:0072562)
1.0 3.9 GO:0097450 astrocyte end-foot(GO:0097450)
1.3 3.8 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
1.3 3.8 GO:0071953 elastic fiber(GO:0071953)
0.0 3.7 GO:0005604 basement membrane(GO:0005604)
0.0 3.7 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 3.6 GO:0005902 microvillus(GO:0005902)
0.0 3.4 GO:0016528 sarcoplasm(GO:0016528)
0.0 3.3 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 3.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.4 2.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 2.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 2.1 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 2.1 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 122 entries
Log-likelihood per target Total log-likelihoodTermDescription
6.9 27.7 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.5 7.4 GO:0008430 selenium binding(GO:0008430)
0.1 7.4 GO:0005178 integrin binding(GO:0005178)
1.1 6.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.1 6.6 GO:0016936 galactoside binding(GO:0016936)
0.2 6.0 GO:0005504 fatty acid binding(GO:0005504)
2.0 5.9 GO:0005534 galactose binding(GO:0005534)
0.1 4.6 GO:0019003 GDP binding(GO:0019003)
0.2 3.9 GO:0030506 ankyrin binding(GO:0030506)
1.0 3.8 GO:0004859 phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834)
0.3 3.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.9 3.5 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.2 3.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.4 3.2 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0 2.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 2.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 2.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 2.5 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 2.5 GO:0008022 protein C-terminus binding(GO:0008022)
0.3 2.4 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)