Motif ID: Nfix

Z-value: 0.845


Transcription factors associated with Nfix:

Gene SymbolEntrez IDGene Name
Nfix ENSMUSG00000001911.10 Nfix

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfixmm10_v2_chr8_-_84800024_848002830.771.2e-03Click!


Activity profile for motif Nfix.

activity profile for motif Nfix


Sorted Z-values histogram for motif Nfix

Sorted Z-values for motif Nfix



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfix

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_16014457 2.273 ENSMUST00000164993.1
 Inhba
inhibin beta-A
chr5_+_66968961 1.684 ENSMUST00000132991.1
 Limch1
LIM and calponin homology domains 1
chr4_+_42035113 1.649 ENSMUST00000098127.1
 Gm10597
predicted gene 10597
chr13_-_113663670 1.523 ENSMUST00000054650.4
 Hspb3
heat shock protein 3
chr6_-_126166726 1.347 ENSMUST00000112244.2
ENSMUST00000050484.7
 Ntf3

neurotrophin 3

chr10_-_109010955 1.165 ENSMUST00000105276.1
ENSMUST00000064054.7
 Syt1

synaptotagmin I

chr4_-_42034726 1.065 ENSMUST00000084677.2
 Gm21093
predicted gene, 21093
chr18_+_34247685 1.051 ENSMUST00000066133.6
 Apc
adenomatosis polyposis coli
chr6_-_99044414 1.034 ENSMUST00000177507.1
ENSMUST00000123992.1
 Foxp1

forkhead box P1

chr7_-_134232005 1.021 ENSMUST00000134504.1
 Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr1_-_56969827 1.005 ENSMUST00000176759.1
 Satb2
special AT-rich sequence binding protein 2
chr5_+_66745835 0.999 ENSMUST00000101164.4
ENSMUST00000118242.1
ENSMUST00000119854.1
ENSMUST00000117601.1
 Limch1



LIM and calponin homology domains 1



chr19_+_44333092 0.980 ENSMUST00000058856.8
 Scd4
stearoyl-coenzyme A desaturase 4
chr13_-_97747373 0.970 ENSMUST00000123535.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr16_+_41532851 0.951 ENSMUST00000078873.4
 Lsamp
limbic system-associated membrane protein
chr3_-_127408937 0.916 ENSMUST00000183095.1
ENSMUST00000182610.1
 Ank2

ankyrin 2, brain

chr16_+_78930940 0.901 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
 Chodl


chondrolectin


chr3_-_127409014 0.892 ENSMUST00000182008.1
ENSMUST00000182711.1
ENSMUST00000182547.1
 Ank2


ankyrin 2, brain


chr4_+_42714926 0.879 ENSMUST00000178454.1
 Gm21955
predicted gene, 21955
chr4_+_102570065 0.858 ENSMUST00000097950.2
 Pde4b
phosphodiesterase 4B, cAMP specific

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 75 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.8 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 2.6 GO:0031032 actomyosin structure organization(GO:0031032)
0.5 2.3 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.2 2.3 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.6 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.3 1.3 GO:0007403 glial cell fate determination(GO:0007403)
0.4 1.2 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1 1.2 GO:0005513 detection of calcium ion(GO:0005513)
0.3 1.1 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.3 1.0 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.2 1.0 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 1.0 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 1.0 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 0.9 GO:0019532 oxalate transport(GO:0019532)
0.0 0.9 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 0.8 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 0.8 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.8 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.2 0.7 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.8 GO:0031430 M band(GO:0031430)
0.8 2.3 GO:0043512 inhibin A complex(GO:0043512)
0.1 2.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.2 GO:0031045 dense core granule(GO:0031045)
0.1 1.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.8 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.6 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0044301 climbing fiber(GO:0044301) parallel fiber(GO:1990032)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.6 GO:0030552 cAMP binding(GO:0030552)
0.4 2.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 1.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 1.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 1.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 1.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 1.0 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.2 1.0 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 0.8 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.8 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.1 0.7 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.6 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.6 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.6 GO:0005044 scavenger receptor activity(GO:0005044)