Motif ID: Nfkb2

Z-value: 1.060


Transcription factors associated with Nfkb2:

Gene SymbolEntrez IDGene Name
Nfkb2 ENSMUSG00000025225.8 Nfkb2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfkb2mm10_v2_chr19_+_46304709_46304811-0.273.4e-01Click!


Activity profile for motif Nfkb2.

activity profile for motif Nfkb2


Sorted Z-values histogram for motif Nfkb2

Sorted Z-values for motif Nfkb2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfkb2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_153740344 5.340 ENSMUST00000027748.7
Rgs16
regulator of G-protein signaling 16
chr11_-_33147400 4.605 ENSMUST00000020507.7
Fgf18
fibroblast growth factor 18
chr14_-_30607808 3.516 ENSMUST00000112207.1
ENSMUST00000112206.1
ENSMUST00000112202.1
ENSMUST00000112203.1
Prkcd



protein kinase C, delta



chr14_-_30626196 3.200 ENSMUST00000112210.3
ENSMUST00000112211.2
ENSMUST00000112208.1
Prkcd


protein kinase C, delta


chr2_+_172550761 2.144 ENSMUST00000099058.3
Tfap2c
transcription factor AP-2, gamma
chr2_+_172550991 1.993 ENSMUST00000170744.1
Tfap2c
transcription factor AP-2, gamma
chr7_+_29289300 1.864 ENSMUST00000048187.4
Ppp1r14a
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr1_+_74791516 1.567 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr19_+_7268296 1.418 ENSMUST00000066646.4
Rcor2
REST corepressor 2
chrX_+_163909132 1.397 ENSMUST00000033734.7
ENSMUST00000112294.2
Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chrX_+_163908982 1.276 ENSMUST00000069041.8
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr11_-_54962903 1.059 ENSMUST00000108885.1
ENSMUST00000102730.2
ENSMUST00000018482.6
ENSMUST00000108886.1
ENSMUST00000102731.1
Tnip1




TNFAIP3 interacting protein 1




chr11_-_70656467 0.995 ENSMUST00000131642.1
Gm12319
predicted gene 12319
chr1_+_167001457 0.939 ENSMUST00000126198.1
Fam78b
family with sequence similarity 78, member B
chr5_+_110544326 0.884 ENSMUST00000040001.7
Galnt9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9
chr15_-_102246439 0.724 ENSMUST00000063339.7
Rarg
retinoic acid receptor, gamma
chr3_-_107760221 0.691 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
Csf1


colony stimulating factor 1 (macrophage)


chr3_-_116424007 0.690 ENSMUST00000090464.4
Cdc14a
CDC14 cell division cycle 14A
chr3_-_116423930 0.677 ENSMUST00000106491.2
Cdc14a
CDC14 cell division cycle 14A
chr1_+_167001417 0.670 ENSMUST00000165874.1
Fam78b
family with sequence similarity 78, member B
chr8_+_79028317 0.633 ENSMUST00000087927.4
ENSMUST00000098614.2
Zfp827

zinc finger protein 827

chr8_+_79028587 0.603 ENSMUST00000119254.1
Zfp827
zinc finger protein 827
chr7_+_19176416 0.529 ENSMUST00000117338.1
Eml2
echinoderm microtubule associated protein like 2
chr3_+_97658212 0.523 ENSMUST00000045743.6
Prkab2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr4_+_100776664 0.514 ENSMUST00000030257.8
ENSMUST00000097955.2
Cachd1

cache domain containing 1

chr5_+_135887988 0.496 ENSMUST00000111155.1
Hspb1
heat shock protein 1
chr2_-_102451792 0.476 ENSMUST00000099678.3
Fjx1
four jointed box 1 (Drosophila)
chr17_+_35379608 0.446 ENSMUST00000081435.4
H2-Q4
histocompatibility 2, Q region locus 4
chr11_+_77686155 0.439 ENSMUST00000100802.4
ENSMUST00000181023.1
Nufip2

nuclear fragile X mental retardation protein interacting protein 2

chr15_-_76918010 0.413 ENSMUST00000048854.7
Zfp647
zinc finger protein 647
chr4_-_125127817 0.398 ENSMUST00000036188.7
Zc3h12a
zinc finger CCCH type containing 12A
chr11_+_70657196 0.371 ENSMUST00000157027.1
ENSMUST00000072841.5
ENSMUST00000108548.1
ENSMUST00000126241.1
Eno3



enolase 3, beta muscle



chr10_-_59221757 0.358 ENSMUST00000165971.1
Sept10
septin 10
chr19_+_6341121 0.338 ENSMUST00000025897.6
ENSMUST00000130382.1
Map4k2

mitogen-activated protein kinase kinase kinase kinase 2

chr7_+_3290553 0.332 ENSMUST00000096744.5
Myadm
myeloid-associated differentiation marker
chr10_+_80702649 0.300 ENSMUST00000095426.3
Izumo4
IZUMO family member 4
chr14_-_118237016 0.297 ENSMUST00000170662.1
Sox21
SRY-box containing gene 21
chr2_-_37422869 0.269 ENSMUST00000112936.1
ENSMUST00000112934.1
Rc3h2

ring finger and CCCH-type zinc finger domains 2

chr1_+_34801704 0.263 ENSMUST00000047664.9
Arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr5_-_137531204 0.245 ENSMUST00000150063.2
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr11_-_84870812 0.242 ENSMUST00000168434.1
Ggnbp2
gametogenetin binding protein 2
chr1_+_135132693 0.233 ENSMUST00000049449.4
Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chr9_-_44735189 0.229 ENSMUST00000034611.8
Phldb1
pleckstrin homology-like domain, family B, member 1
chr5_-_114690906 0.225 ENSMUST00000112212.1
ENSMUST00000112214.1
Gltp

glycolipid transfer protein

chr11_-_84870712 0.214 ENSMUST00000170741.1
ENSMUST00000172405.1
ENSMUST00000100686.3
ENSMUST00000108081.2
Ggnbp2



gametogenetin binding protein 2



chr4_-_42168603 0.214 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr14_+_55591708 0.212 ENSMUST00000019443.8
Rnf31
ring finger protein 31
chr11_-_84870188 0.205 ENSMUST00000154915.2
Ggnbp2
gametogenetin binding protein 2
chr7_-_126200413 0.195 ENSMUST00000163959.1
Xpo6
exportin 6
chr18_-_77565050 0.186 ENSMUST00000182153.1
ENSMUST00000182146.1
ENSMUST00000026494.7
ENSMUST00000182024.1
Rnf165



ring finger protein 165



chr10_-_89686250 0.164 ENSMUST00000092227.5
ENSMUST00000174252.1
Scyl2

SCY1-like 2 (S. cerevisiae)

chr8_+_108714644 0.137 ENSMUST00000043896.8
Zfhx3
zinc finger homeobox 3
chr1_+_135133272 0.130 ENSMUST00000167080.1
Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chr2_-_3419066 0.128 ENSMUST00000115082.3
Meig1
meiosis expressed gene 1
chr1_-_5019342 0.127 ENSMUST00000002533.8
Rgs20
regulator of G-protein signaling 20
chr1_-_156718989 0.124 ENSMUST00000122424.1
Fam20b
family with sequence similarity 20, member B
chr1_-_63114255 0.123 ENSMUST00000153992.1
ENSMUST00000165066.1
ENSMUST00000172416.1
ENSMUST00000137511.1
Ino80d



INO80 complex subunit D



chr2_-_32312162 0.114 ENSMUST00000155269.1
Dnm1
dynamin 1
chr7_-_126200474 0.109 ENSMUST00000168189.1
Xpo6
exportin 6
chr1_-_156718894 0.102 ENSMUST00000086153.6
Fam20b
family with sequence similarity 20, member B
chr5_-_137530990 0.099 ENSMUST00000132525.1
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr11_+_101176041 0.093 ENSMUST00000103109.3
Cntnap1
contactin associated protein-like 1
chr17_-_34287770 0.076 ENSMUST00000174751.1
ENSMUST00000040655.6
H2-Aa

histocompatibility 2, class II antigen A, alpha

chr7_-_126200397 0.052 ENSMUST00000009344.9
Xpo6
exportin 6
chr17_+_35424842 0.051 ENSMUST00000174699.1
H2-Q6
histocompatibility 2, Q region locus 6
chr11_-_84870646 0.026 ENSMUST00000018547.2
Ggnbp2
gametogenetin binding protein 2
chr14_+_80000292 0.026 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr3_+_117575268 0.009 ENSMUST00000039564.6
4833424O15Rik
RIKEN cDNA 4833424O15 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
1.3 6.7 GO:0006680 glucosylceramide catabolic process(GO:0006680) negative regulation of filopodium assembly(GO:0051490)
1.2 4.6 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.2 0.7 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.2 1.4 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.2 0.7 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.2 1.6 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 0.4 GO:0045472 response to ether(GO:0045472) negative regulation of interleukin-1 beta secretion(GO:0050713) negative regulation of interferon-gamma secretion(GO:1902714) negative regulation of tumor necrosis factor secretion(GO:1904468)
0.1 1.1 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1 0.5 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.1 0.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 2.8 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.1 0.2 GO:0046836 glycolipid transport(GO:0046836)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.5 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0 0.3 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 1.7 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.3 GO:0006903 vesicle targeting(GO:0006903)
0.0 5.3 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.2 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.2 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 6.3 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 2.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.9 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 5.7 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.7 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
1.5 4.6 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2 1.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.2 GO:0017089 glycolipid transporter activity(GO:0017089)
0.1 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 4.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.7 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 1.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 3.0 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 1.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 1.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 5.5 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.9 GO:0035496 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062)
0.0 0.2 GO:0042556 cobinamide kinase activity(GO:0008819) phytol kinase activity(GO:0010276) phenol kinase activity(GO:0018720) cyclin-dependent protein kinase activating kinase regulator activity(GO:0019914) inositol tetrakisphosphate 2-kinase activity(GO:0032942) heptose 7-phosphate kinase activity(GO:0033785) aminoglycoside phosphotransferase activity(GO:0034071) eukaryotic elongation factor-2 kinase regulator activity(GO:0042556) eukaryotic elongation factor-2 kinase activator activity(GO:0042557) LPPG:FO 2-phospho-L-lactate transferase activity(GO:0043743) cytidine kinase activity(GO:0043771) glycerate 2-kinase activity(GO:0043798) (S)-lactate 2-kinase activity(GO:0043841) phosphoserine:homoserine phosphotransferase activity(GO:0043899) L-seryl-tRNA(Sec) kinase activity(GO:0043915) phosphocholine transferase activity(GO:0044605) GTP-dependent polynucleotide kinase activity(GO:0051735) farnesol kinase activity(GO:0052668) CTP:2-trans,-6-trans-farnesol kinase activity(GO:0052669) geraniol kinase activity(GO:0052670) geranylgeraniol kinase activity(GO:0052671) CTP:geranylgeraniol kinase activity(GO:0052672) prenol kinase activity(GO:0052673) 1-phosphatidylinositol-5-kinase activity(GO:0052810) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.5 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 0.1 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)