Motif ID: Nhlh1

Z-value: 1.030


Transcription factors associated with Nhlh1:

Gene SymbolEntrez IDGene Name
Nhlh1 ENSMUSG00000051251.3 Nhlh1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nhlh1mm10_v2_chr1_-_172057573_172057598-0.136.5e-01Click!


Activity profile for motif Nhlh1.

activity profile for motif Nhlh1


Sorted Z-values histogram for motif Nhlh1

Sorted Z-values for motif Nhlh1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nhlh1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_122289297 1.703 ENSMUST00000064989.5
ENSMUST00000064921.4
 Prkcb

protein kinase C, beta

chr4_+_137862270 1.635 ENSMUST00000130407.1
 Ece1
endothelin converting enzyme 1
chr2_+_158375638 1.201 ENSMUST00000109488.1
 Snhg11
small nucleolar RNA host gene 11
chr13_-_23622502 1.188 ENSMUST00000062045.2
 Hist1h1e
histone cluster 1, H1e
chrX_+_35888808 0.904 ENSMUST00000033419.6
 Dock11
dedicator of cytokinesis 11
chr16_+_91269759 0.894 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr10_-_30803075 0.826 ENSMUST00000068567.4
 Ncoa7
nuclear receptor coactivator 7
chr1_+_174501796 0.780 ENSMUST00000030039.7
 Fmn2
formin 2
chr10_+_98915117 0.767 ENSMUST00000020107.7
 Atp2b1
ATPase, Ca++ transporting, plasma membrane 1
chr14_+_34673888 0.767 ENSMUST00000048263.7
 Wapal
wings apart-like homolog (Drosophila)
chr1_+_129273344 0.749 ENSMUST00000073527.6
ENSMUST00000040311.7
 Thsd7b

thrombospondin, type I, domain containing 7B

chr14_+_34673948 0.738 ENSMUST00000090027.3
 Wapal
wings apart-like homolog (Drosophila)
chr3_-_84304762 0.715 ENSMUST00000107692.1
 Trim2
tripartite motif-containing 2
chr15_-_71727815 0.698 ENSMUST00000022953.8
 Fam135b
family with sequence similarity 135, member B
chr4_+_41903610 0.698 ENSMUST00000098128.3
 Gm21541
predicted gene, 21541
chr11_-_6475992 0.697 ENSMUST00000179343.1
 Purb
purine rich element binding protein B
chr9_+_67840386 0.694 ENSMUST00000077879.5
 Vps13c
vacuolar protein sorting 13C (yeast)
chr2_-_60963192 0.683 ENSMUST00000028347.6
 Rbms1
RNA binding motif, single stranded interacting protein 1
chr9_-_57836706 0.670 ENSMUST00000164010.1
ENSMUST00000171444.1
ENSMUST00000098686.3
 Arid3b


AT rich interactive domain 3B (BRIGHT-like)


chr2_-_39190687 0.659 ENSMUST00000142872.1
ENSMUST00000038874.5
 Scai

suppressor of cancer cell invasion


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 299 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 1.8 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.3 1.8 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.2 1.2 GO:0016584 nucleosome positioning(GO:0016584)
0.4 1.1 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.0 1.1 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 1.0 GO:0007608 sensory perception of smell(GO:0007608)
0.3 0.8 GO:0040009 regulation of growth rate(GO:0040009)
0.3 0.8 GO:0070649 meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649)
0.1 0.8 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.8 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.8 GO:0030199 collagen fibril organization(GO:0030199)
0.2 0.7 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.1 0.7 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 0.7 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 0.7 GO:0051409 response to nitrosative stress(GO:0051409)
0.1 0.7 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.7 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.7 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.2 0.6 GO:0071139 resolution of recombination intermediates(GO:0071139)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 109 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 1.8 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 1.8 GO:0044815 DNA packaging complex(GO:0044815)
0.0 1.4 GO:0031526 brush border membrane(GO:0031526)
0.0 1.1 GO:0043034 costamere(GO:0043034)
0.1 1.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.8 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.8 GO:0005801 cis-Golgi network(GO:0005801)
0.2 0.7 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.6 GO:0032389 MutLalpha complex(GO:0032389)
0.1 0.6 GO:0070695 FHF complex(GO:0070695)
0.1 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.6 GO:0005915 zonula adherens(GO:0005915)
0.0 0.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.6 GO:0005902 microvillus(GO:0005902)
0.2 0.5 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.1 0.5 GO:0008091 spectrin(GO:0008091)
0.1 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 182 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 2.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.1 GO:0008017 microtubule binding(GO:0008017)
0.2 1.7 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 1.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 0.9 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.9 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.7 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.7 GO:0070410 co-SMAD binding(GO:0070410)
0.2 0.6 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.1 0.6 GO:0051880 Y-form DNA binding(GO:0000403) bubble DNA binding(GO:0000405) G-quadruplex DNA binding(GO:0051880)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)