Motif ID: Nkx3-1
Z-value: 0.855
Transcription factors associated with Nkx3-1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nkx3-1 | ENSMUSG00000022061.8 | Nkx3-1 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.3 | GO:0035617 | stress granule disassembly(GO:0035617) |
0.3 | 2.5 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
0.3 | 1.3 | GO:0030242 | pexophagy(GO:0030242) |
0.2 | 0.6 | GO:0006011 | UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255) |
0.2 | 0.6 | GO:0010845 | positive regulation of reciprocal meiotic recombination(GO:0010845) |
0.2 | 0.5 | GO:0070093 | negative regulation of glucagon secretion(GO:0070093) |
0.2 | 0.5 | GO:0090327 | negative regulation of locomotion involved in locomotory behavior(GO:0090327) |
0.1 | 0.4 | GO:1901552 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
0.1 | 0.8 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) amylase secretion(GO:0036394) |
0.1 | 0.6 | GO:0090310 | negative regulation of methylation-dependent chromatin silencing(GO:0090310) |
0.1 | 0.4 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
0.1 | 0.6 | GO:0006561 | proline biosynthetic process(GO:0006561) |
0.1 | 0.2 | GO:0002765 | immune response-inhibiting signal transduction(GO:0002765) |
0.1 | 0.4 | GO:0036337 | Fas signaling pathway(GO:0036337) |
0.1 | 0.9 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.1 | 0.5 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
0.1 | 0.8 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
0.1 | 0.4 | GO:0072257 | metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307) |
0.1 | 0.4 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
0.1 | 0.7 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
0.1 | 0.6 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
0.1 | 0.2 | GO:0045819 | positive regulation of glycogen catabolic process(GO:0045819) |
0.1 | 0.4 | GO:0009301 | snRNA transcription(GO:0009301) |
0.1 | 0.2 | GO:0015938 | coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) |
0.0 | 0.6 | GO:0009143 | nucleoside triphosphate catabolic process(GO:0009143) |
0.0 | 0.1 | GO:0007525 | somatic muscle development(GO:0007525) |
0.0 | 0.4 | GO:0071763 | nuclear membrane organization(GO:0071763) |
0.0 | 0.1 | GO:2000642 | negative regulation of early endosome to late endosome transport(GO:2000642) |
0.0 | 0.2 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
0.0 | 0.3 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
0.0 | 0.2 | GO:0060018 | astrocyte fate commitment(GO:0060018) |
0.0 | 0.2 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
0.0 | 0.4 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
0.0 | 0.1 | GO:0097167 | circadian regulation of translation(GO:0097167) |
0.0 | 0.1 | GO:2000407 | positive regulation of necrotic cell death(GO:0010940) regulation of T cell extravasation(GO:2000407) |
0.0 | 0.2 | GO:0060056 | mammary gland involution(GO:0060056) |
0.0 | 0.3 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
0.0 | 0.1 | GO:0061668 | mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775) |
0.0 | 0.2 | GO:0033147 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) |
0.0 | 0.5 | GO:0015858 | nucleoside transport(GO:0015858) |
0.0 | 0.2 | GO:0018377 | N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377) |
0.0 | 0.3 | GO:2000381 | negative regulation of mesoderm development(GO:2000381) |
0.0 | 0.1 | GO:0033615 | mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615) |
0.0 | 0.2 | GO:0006370 | 7-methylguanosine mRNA capping(GO:0006370) |
0.0 | 0.2 | GO:0034312 | diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520) |
0.0 | 0.4 | GO:0021692 | cerebellar Purkinje cell layer morphogenesis(GO:0021692) |
0.0 | 0.4 | GO:0031116 | positive regulation of microtubule polymerization(GO:0031116) |
0.0 | 0.3 | GO:0070986 | left/right axis specification(GO:0070986) |
0.0 | 0.1 | GO:0006046 | N-acetylglucosamine catabolic process(GO:0006046) |
0.0 | 0.4 | GO:0006298 | mismatch repair(GO:0006298) |
0.0 | 0.2 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
0.0 | 0.3 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
0.0 | 0.2 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
0.0 | 0.2 | GO:0070633 | transepithelial transport(GO:0070633) |
0.0 | 0.3 | GO:0006379 | mRNA cleavage(GO:0006379) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.5 | GO:0031430 | M band(GO:0031430) |
0.1 | 0.4 | GO:0005712 | chiasma(GO:0005712) |
0.1 | 0.4 | GO:0008091 | spectrin(GO:0008091) |
0.1 | 1.3 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.1 | 0.8 | GO:0032591 | dendritic spine membrane(GO:0032591) |
0.1 | 0.5 | GO:0044327 | dendritic spine head(GO:0044327) |
0.1 | 0.2 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
0.1 | 0.2 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
0.1 | 0.5 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
0.0 | 0.4 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
0.0 | 1.6 | GO:0032420 | stereocilium(GO:0032420) |
0.0 | 0.9 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.0 | 0.3 | GO:0036038 | gamma-tubulin complex(GO:0000930) MKS complex(GO:0036038) |
0.0 | 0.1 | GO:0097342 | ripoptosome(GO:0097342) |
0.0 | 0.0 | GO:0097447 | dendritic tree(GO:0097447) |
0.0 | 0.4 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.0 | 0.1 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
0.0 | 0.4 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.0 | 0.1 | GO:0070938 | contractile ring(GO:0070938) |
0.0 | 0.2 | GO:0042611 | MHC protein complex(GO:0042611) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.5 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) |
0.2 | 0.6 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
0.1 | 0.6 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
0.1 | 2.5 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.1 | 1.1 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.1 | 0.2 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
0.1 | 0.8 | GO:0008758 | thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606) |
0.1 | 0.5 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.1 | 0.8 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
0.1 | 0.6 | GO:0032557 | pyrimidine ribonucleotide binding(GO:0032557) |
0.1 | 0.2 | GO:0000402 | open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402) |
0.1 | 0.4 | GO:0032184 | SUMO polymer binding(GO:0032184) |
0.0 | 0.4 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
0.0 | 0.4 | GO:0070568 | guanylyltransferase activity(GO:0070568) |
0.0 | 0.9 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.0 | 1.3 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
0.0 | 0.3 | GO:0003847 | 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) |
0.0 | 0.5 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
0.0 | 0.6 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
0.0 | 0.5 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.0 | 0.4 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
0.0 | 0.1 | GO:0004342 | glucosamine-6-phosphate deaminase activity(GO:0004342) |
0.0 | 0.4 | GO:0016661 | oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661) |
0.0 | 0.4 | GO:0005521 | lamin binding(GO:0005521) |
0.0 | 0.8 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 0.5 | GO:0031690 | adrenergic receptor binding(GO:0031690) |
0.0 | 0.2 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.0 | 0.6 | GO:0004120 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715) |
0.0 | 0.5 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 0.2 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.0 | 0.2 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |