Motif ID: Nkx6-3_Dbx2_Barx2
Z-value: 0.801
Transcription factors associated with Nkx6-3_Dbx2_Barx2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Barx2 | ENSMUSG00000032033.10 | Barx2 |
Dbx2 | ENSMUSG00000045608.6 | Dbx2 |
Nkx6-3 | ENSMUSG00000063672.6 | Nkx6-3 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Dbx2 | mm10_v2_chr15_-_95655960_95655960 | 0.69 | 6.3e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.3 | GO:0009193 | pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048) |
0.7 | 5.0 | GO:0019532 | oxalate transport(GO:0019532) |
0.3 | 0.9 | GO:0072204 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
0.3 | 1.3 | GO:0015788 | UDP-N-acetylglucosamine transport(GO:0015788) |
0.2 | 0.7 | GO:2000852 | regulation of corticosterone secretion(GO:2000852) |
0.2 | 0.9 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
0.2 | 0.6 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
0.2 | 0.5 | GO:0035633 | maintenance of blood-brain barrier(GO:0035633) |
0.1 | 0.4 | GO:1903903 | regulation of establishment of T cell polarity(GO:1903903) |
0.1 | 0.8 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
0.1 | 0.4 | GO:1901642 | purine nucleoside transmembrane transport(GO:0015860) purine-containing compound transmembrane transport(GO:0072530) nucleoside transmembrane transport(GO:1901642) nucleotide transmembrane transport(GO:1901679) |
0.1 | 0.4 | GO:1900170 | prolactin signaling pathway(GO:0038161) negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
0.1 | 0.4 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
0.1 | 2.3 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.1 | 0.2 | GO:2000564 | CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
0.1 | 0.5 | GO:0010273 | detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
0.1 | 0.5 | GO:0042415 | norepinephrine metabolic process(GO:0042415) |
0.1 | 0.8 | GO:0033572 | transferrin transport(GO:0033572) |
0.1 | 1.6 | GO:0071398 | cellular response to fatty acid(GO:0071398) |
0.1 | 0.3 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
0.0 | 0.3 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.0 | 0.2 | GO:0010920 | negative regulation of inositol phosphate biosynthetic process(GO:0010920) |
0.0 | 0.2 | GO:0033762 | response to glucagon(GO:0033762) |
0.0 | 0.4 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
0.0 | 0.2 | GO:0051012 | microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856) |
0.0 | 0.5 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
0.0 | 0.1 | GO:0072008 | glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144) |
0.0 | 0.1 | GO:2001268 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268) |
0.0 | 0.9 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
0.0 | 0.1 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
0.0 | 2.5 | GO:0042742 | defense response to bacterium(GO:0042742) |
0.0 | 0.1 | GO:0060690 | epithelial cell differentiation involved in salivary gland development(GO:0060690) |
0.0 | 0.3 | GO:0016486 | peptide hormone processing(GO:0016486) |
0.0 | 0.1 | GO:0002544 | chronic inflammatory response(GO:0002544) |
0.0 | 0.5 | GO:0019228 | neuronal action potential(GO:0019228) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.4 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
0.1 | 2.3 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
0.1 | 0.4 | GO:0036449 | microtubule minus-end(GO:0036449) |
0.0 | 2.7 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.0 | 0.4 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
0.0 | 0.3 | GO:0005796 | Golgi lumen(GO:0005796) |
0.0 | 0.6 | GO:0043205 | fibril(GO:0043205) |
0.0 | 0.1 | GO:0042585 | germinal vesicle(GO:0042585) |
0.0 | 0.2 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
0.0 | 0.2 | GO:0045275 | respiratory chain complex III(GO:0045275) |
0.0 | 0.1 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
0.0 | 0.2 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.0 | 1.2 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 0.1 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
0.0 | 0.2 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.0 | 2.8 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 5.0 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
0.3 | 2.3 | GO:0045134 | uridine-diphosphatase activity(GO:0045134) |
0.3 | 0.9 | GO:0019770 | IgG receptor activity(GO:0019770) |
0.1 | 0.4 | GO:0015217 | ADP transmembrane transporter activity(GO:0015217) coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122) |
0.1 | 0.6 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
0.1 | 2.3 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.1 | 0.9 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.1 | 0.3 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
0.1 | 0.3 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.1 | 0.9 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.1 | 0.5 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.1 | 1.1 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.1 | 1.3 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
0.1 | 0.4 | GO:0018741 | alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902) |
0.0 | 1.6 | GO:0005504 | fatty acid binding(GO:0005504) |
0.0 | 0.2 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
0.0 | 1.3 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 0.2 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.0 | 0.1 | GO:0034235 | GPI anchor binding(GO:0034235) |
0.0 | 0.7 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
0.0 | 0.1 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
0.0 | 0.2 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.0 | 0.4 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.0 | 0.2 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 0.5 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 0.0 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
0.0 | 0.2 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.0 | 0.8 | GO:0017022 | myosin binding(GO:0017022) |
0.0 | 0.4 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
0.0 | 0.5 | GO:0004601 | peroxidase activity(GO:0004601) |