Motif ID: Nkx6-3_Dbx2_Barx2

Z-value: 0.801

Transcription factors associated with Nkx6-3_Dbx2_Barx2:

Gene SymbolEntrez IDGene Name
Barx2 ENSMUSG00000032033.10 Barx2
Dbx2 ENSMUSG00000045608.6 Dbx2
Nkx6-3 ENSMUSG00000063672.6 Nkx6-3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dbx2mm10_v2_chr15_-_95655960_956559600.696.3e-03Click!


Activity profile for motif Nkx6-3_Dbx2_Barx2.

activity profile for motif Nkx6-3_Dbx2_Barx2


Sorted Z-values histogram for motif Nkx6-3_Dbx2_Barx2

Sorted Z-values for motif Nkx6-3_Dbx2_Barx2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx6-3_Dbx2_Barx2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 132 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_14621805 2.485 ENSMUST00000042221.7
 Slc26a7
solute carrier family 26, member 7
chr8_-_21906412 2.352 ENSMUST00000051965.4
 Defb11
defensin beta 11
chr14_+_69347587 2.341 ENSMUST00000064831.5
 Entpd4
ectonucleoside triphosphate diphosphohydrolase 4
chr13_+_94083490 2.236 ENSMUST00000156071.1
 Lhfpl2
lipoma HMGIC fusion partner-like 2
chr5_-_70842617 1.881 ENSMUST00000031119.1
 Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr4_+_136143497 1.575 ENSMUST00000008016.2
 Id3
inhibitor of DNA binding 3
chr4_-_14621494 1.476 ENSMUST00000149633.1
 Slc26a7
solute carrier family 26, member 7
chr7_+_51880312 1.283 ENSMUST00000145049.1
 Gas2
growth arrest specific 2
chr5_-_62766153 1.279 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_+_125136692 1.279 ENSMUST00000099452.2
 Ctxn2
cortexin 2
chr3_-_116712644 1.279 ENSMUST00000029569.2
 Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chrX_+_169685191 1.159 ENSMUST00000112104.1
ENSMUST00000112107.1
 Mid1

midline 1

chr17_-_45659312 1.141 ENSMUST00000120717.1
 Capn11
calpain 11
chr6_-_137169710 1.120 ENSMUST00000117919.1
 Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr4_-_14621669 1.005 ENSMUST00000143105.1
 Slc26a7
solute carrier family 26, member 7
chr7_+_57387304 0.953 ENSMUST00000085241.5
 Gm9962
predicted gene 9962
chr2_+_109917639 0.906 ENSMUST00000046548.7
ENSMUST00000111037.2
 Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr7_-_45103747 0.888 ENSMUST00000003512.7
 Fcgrt
Fc receptor, IgG, alpha chain transporter
chr5_-_43981757 0.841 ENSMUST00000061299.7
 Fgfbp1
fibroblast growth factor binding protein 1
chrX_+_170009892 0.767 ENSMUST00000180251.1
 Gm21887
predicted gene, 21887

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 5.0 GO:0019532 oxalate transport(GO:0019532)
0.0 2.5 GO:0042742 defense response to bacterium(GO:0042742)
0.8 2.3 GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.1 2.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 1.6 GO:0071398 cellular response to fatty acid(GO:0071398)
0.3 1.3 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.3 0.9 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.2 0.9 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.9 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 0.8 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.8 GO:0033572 transferrin transport(GO:0033572)
0.2 0.7 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.2 0.6 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 0.5 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.1 0.5 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 0.5 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.5 GO:0019228 neuronal action potential(GO:0019228)
0.1 0.4 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.1 0.4 GO:1901642 purine nucleoside transmembrane transport(GO:0015860) purine-containing compound transmembrane transport(GO:0072530) nucleoside transmembrane transport(GO:1901642) nucleotide transmembrane transport(GO:1901679)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 2.3 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.6 GO:0043205 fibril(GO:0043205)
0.1 0.4 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0045275 respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 5.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.3 2.3 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.1 2.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.6 GO:0005504 fatty acid binding(GO:0005504)
0.1 1.3 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 1.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3 0.9 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.9 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.8 GO:0017022 myosin binding(GO:0017022)
0.0 0.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.6 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0004601 peroxidase activity(GO:0004601)
0.1 0.4 GO:0015217 ADP transmembrane transporter activity(GO:0015217) coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.4 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.4 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)