Motif ID: Nr0b1

Z-value: 0.552


Transcription factors associated with Nr0b1:

Gene SymbolEntrez IDGene Name
Nr0b1 ENSMUSG00000025056.4 Nr0b1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr0b1mm10_v2_chrX_+_86191764_861917820.244.2e-01Click!


Activity profile for motif Nr0b1.

activity profile for motif Nr0b1


Sorted Z-values histogram for motif Nr0b1

Sorted Z-values for motif Nr0b1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr0b1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_79500081 0.937 ENSMUST00000181511.2
ENSMUST00000182937.1
 AI854517

expressed sequence AI854517

chr7_+_79500018 0.929 ENSMUST00000182495.1
ENSMUST00000183043.1
 AI854517

expressed sequence AI854517

chr1_+_140246216 0.836 ENSMUST00000119786.1
ENSMUST00000120796.1
ENSMUST00000060201.8
ENSMUST00000120709.1
 Kcnt2



potassium channel, subfamily T, member 2



chr13_-_29984219 0.725 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3
chr2_-_54085542 0.680 ENSMUST00000100089.2
 Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr1_-_9700209 0.627 ENSMUST00000088658.4
 Mybl1
myeloblastosis oncogene-like 1
chr11_+_77930800 0.577 ENSMUST00000093995.3
ENSMUST00000000646.7
 Sez6

seizure related gene 6

chr7_+_19359740 0.551 ENSMUST00000140836.1
 Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr18_+_35829798 0.549 ENSMUST00000060722.6
 Cxxc5
CXXC finger 5
chr19_-_46039442 0.509 ENSMUST00000137771.1
 Ldb1
LIM domain binding 1
chr11_+_102604370 0.464 ENSMUST00000057893.5
 Fzd2
frizzled homolog 2 (Drosophila)
chr16_-_45844228 0.460 ENSMUST00000076333.5
 Phldb2
pleckstrin homology-like domain, family B, member 2
chr16_-_45844303 0.460 ENSMUST00000036355.6
 Phldb2
pleckstrin homology-like domain, family B, member 2
chr14_+_11553523 0.452 ENSMUST00000022264.6
 Ptprg
protein tyrosine phosphatase, receptor type, G
chr3_-_123690806 0.448 ENSMUST00000154668.1
 Ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr9_+_80165013 0.437 ENSMUST00000035889.8
ENSMUST00000113268.1
 Myo6

myosin VI

chr2_-_65238625 0.426 ENSMUST00000112429.2
ENSMUST00000102726.1
ENSMUST00000112430.1
 Cobll1


Cobl-like 1


chr7_+_19094594 0.376 ENSMUST00000049454.5
 Six5
sine oculis-related homeobox 5
chr5_-_99037342 0.349 ENSMUST00000161490.1
 Prkg2
protein kinase, cGMP-dependent, type II
chr12_+_49385174 0.347 ENSMUST00000110746.1
 3110039M20Rik
RIKEN cDNA 3110039M20 gene
chr10_+_116301374 0.346 ENSMUST00000092167.5
 Ptprb
protein tyrosine phosphatase, receptor type, B
chr10_-_81350389 0.342 ENSMUST00000020454.4
ENSMUST00000105324.2
ENSMUST00000154609.2
ENSMUST00000105323.1
 Hmg20b



high mobility group 20B



chr17_-_23745829 0.319 ENSMUST00000046525.8
 Kremen2
kringle containing transmembrane protein 2
chr7_+_82867327 0.316 ENSMUST00000082237.5
 Mex3b
mex3 homolog B (C. elegans)
chr10_+_39732099 0.300 ENSMUST00000019986.6
 Rev3l
REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)
chr3_-_107458895 0.300 ENSMUST00000009617.8
 Kcnc4
potassium voltage gated channel, Shaw-related subfamily, member 4
chr9_+_80165079 0.287 ENSMUST00000184480.1
 Myo6
myosin VI
chr17_-_70851189 0.282 ENSMUST00000059775.8
 Tgif1
TGFB-induced factor homeobox 1
chr5_-_115436508 0.265 ENSMUST00000078701.3
 4930430O22Rik
RIKEN cDNA 4930430O22 gene
chr5_-_112392213 0.249 ENSMUST00000031291.7
 Asphd2
aspartate beta-hydroxylase domain containing 2
chr4_+_148130883 0.225 ENSMUST00000084129.2
 Mad2l2
MAD2 mitotic arrest deficient-like 2
chr5_+_30913398 0.224 ENSMUST00000031055.5
 Emilin1
elastin microfibril interfacer 1
chr2_+_129198757 0.218 ENSMUST00000028880.3
 Slc20a1
solute carrier family 20, member 1
chr10_-_127666673 0.210 ENSMUST00000026469.2
 Nab2
Ngfi-A binding protein 2
chr5_+_64803513 0.187 ENSMUST00000165536.1
 Klf3
Kruppel-like factor 3 (basic)
chr17_+_34898463 0.172 ENSMUST00000114033.2
ENSMUST00000078061.6
 Ehmt2

euchromatic histone lysine N-methyltransferase 2

chr8_-_85080679 0.163 ENSMUST00000093357.5
 Wdr83
WD repeat domain containing 83
chr11_-_74723829 0.162 ENSMUST00000102520.2
 Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr4_-_132422484 0.149 ENSMUST00000102568.3
 Phactr4
phosphatase and actin regulator 4
chr17_-_80728026 0.148 ENSMUST00000112389.2
ENSMUST00000025089.7
 Map4k3

mitogen-activated protein kinase kinase kinase kinase 3

chr6_+_134830216 0.146 ENSMUST00000111937.1
 Crebl2
cAMP responsive element binding protein-like 2
chr3_-_86920830 0.132 ENSMUST00000029719.8
 Dclk2
doublecortin-like kinase 2
chr16_+_44173239 0.126 ENSMUST00000119746.1
 Gm608
predicted gene 608
chr7_-_80371197 0.121 ENSMUST00000098346.3
 Man2a2
mannosidase 2, alpha 2
chr15_+_98634743 0.121 ENSMUST00000003442.7
 Cacnb3
calcium channel, voltage-dependent, beta 3 subunit
chr19_-_6077183 0.111 ENSMUST00000025711.5
ENSMUST00000160590.1
 Vps51

vacuolar protein sorting 51 homolog (S. cerevisiae)

chr4_+_116221633 0.105 ENSMUST00000030464.7
 Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr1_+_42697146 0.101 ENSMUST00000054883.2
 Pou3f3
POU domain, class 3, transcription factor 3
chr4_-_132422394 0.098 ENSMUST00000152271.1
ENSMUST00000084170.5
 Phactr4

phosphatase and actin regulator 4

chr4_-_129696817 0.096 ENSMUST00000102588.3
 Tmem39b
transmembrane protein 39b
chr15_-_38078842 0.092 ENSMUST00000110336.2
 Ubr5
ubiquitin protein ligase E3 component n-recognin 5
chr8_-_85080652 0.084 ENSMUST00000152785.1
 Wdr83
WD repeat domain containing 83
chr6_+_47454320 0.073 ENSMUST00000031697.8
 Cul1
cullin 1
chr19_-_6128208 0.059 ENSMUST00000025702.7
 Snx15
sorting nexin 15
chr11_+_23306884 0.057 ENSMUST00000180046.1
 Usp34
ubiquitin specific peptidase 34
chr11_+_23306910 0.057 ENSMUST00000137823.1
 Usp34
ubiquitin specific peptidase 34
chr5_+_31193227 0.050 ENSMUST00000031029.8
ENSMUST00000133711.1
ENSMUST00000132471.1
 Snx17


sorting nexin 17


chr7_-_65371210 0.046 ENSMUST00000102592.3
 Tjp1
tight junction protein 1
chr2_+_157279026 0.045 ENSMUST00000116380.2
 Rpn2
ribophorin II
chr13_-_55488038 0.044 ENSMUST00000109921.2
ENSMUST00000109923.2
ENSMUST00000021950.8
 Dbn1


drebrin 1


chr13_-_64274879 0.036 ENSMUST00000109770.1
 Cdc14b
CDC14 cell division cycle 14B
chr15_+_35371498 0.035 ENSMUST00000048646.7
 Vps13b
vacuolar protein sorting 13B (yeast)
chr4_-_148130678 0.032 ENSMUST00000030862.4
 Draxin
dorsal inhibitory axon guidance protein
chr8_-_95434869 0.030 ENSMUST00000034249.6
 Gtl3
gene trap locus 3
chr5_+_121711609 0.026 ENSMUST00000051950.7
 Atxn2
ataxin 2
chr4_-_135971894 0.026 ENSMUST00000105852.1
 Lypla2
lysophospholipase 2
chr11_+_50237002 0.024 ENSMUST00000180443.1
 Gm26542
predicted gene, 26542
chr6_+_134830145 0.023 ENSMUST00000046303.5
 Crebl2
cAMP responsive element binding protein-like 2
chr15_+_80711292 0.022 ENSMUST00000067689.7
 Tnrc6b
trinucleotide repeat containing 6b
chr11_+_105181527 0.021 ENSMUST00000106941.2
 Tlk2
tousled-like kinase 2 (Arabidopsis)
chr2_+_157279065 0.021 ENSMUST00000029171.5
 Rpn2
ribophorin II
chr11_+_105181793 0.020 ENSMUST00000092537.3
ENSMUST00000015107.6
ENSMUST00000145048.1
 Tlk2


tousled-like kinase 2 (Arabidopsis)


chr5_-_31193008 0.017 ENSMUST00000114605.1
ENSMUST00000114603.1
 Eif2b4

eukaryotic translation initiation factor 2B, subunit 4 delta

chr2_-_80581380 0.009 ENSMUST00000111760.2
 Nckap1
NCK-associated protein 1
chr5_+_110230975 0.000 ENSMUST00000031474.7
ENSMUST00000086674.5
 Ankle2

ankyrin repeat and LEM domain containing 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.7 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.5 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.1 0.5 GO:0007223 muscular septum morphogenesis(GO:0003150) Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.1 0.3 GO:0072697 protein localization to cell cortex(GO:0072697)
0.1 0.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.2 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.3 GO:0045759 negative regulation of action potential(GO:0045759)
0.1 0.2 GO:0036166 phenotypic switching(GO:0036166)
0.1 0.2 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.7 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.6 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0072070 loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.0 0.2 GO:0051660 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660) maintenance of centrosome location(GO:0051661) regulation of microtubule motor activity(GO:2000574)
0.0 0.4 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.0 0.1 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.6 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.2 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.0 GO:0010643 cell communication by chemical coupling(GO:0010643) negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.0 0.1 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.3 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.1 0.9 GO:0045180 basal cortex(GO:0045180)
0.0 0.7 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.2 GO:0000235 astral microtubule(GO:0000235)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.6 GO:0097440 apical dendrite(GO:0097440)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.0 GO:1902737 dendritic filopodium(GO:1902737)
0.0 0.6 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.2 GO:0071862 protein phosphatase type 1 activator activity(GO:0071862)
0.1 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)