Motif ID: Nr1h2

Z-value: 0.617


Transcription factors associated with Nr1h2:

Gene SymbolEntrez IDGene Name
Nr1h2 ENSMUSG00000060601.6 Nr1h2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr1h2mm10_v2_chr7_-_44553901_445539550.362.1e-01Click!


Activity profile for motif Nr1h2.

activity profile for motif Nr1h2


Sorted Z-values histogram for motif Nr1h2

Sorted Z-values for motif Nr1h2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr1h2

PNG image of the network

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Top targets:


Showing 1 to 20 of 126 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_53159885 0.839 ENSMUST00000030010.3
 Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr6_-_119544282 0.642 ENSMUST00000119369.1
ENSMUST00000178696.1
 Wnt5b

wingless-related MMTV integration site 5B

chr10_+_26822560 0.617 ENSMUST00000135866.1
 Arhgap18
Rho GTPase activating protein 18
chr7_-_97417730 0.616 ENSMUST00000043077.7
 Thrsp
thyroid hormone responsive
chr15_-_79328201 0.569 ENSMUST00000173163.1
ENSMUST00000047816.8
ENSMUST00000172403.2
ENSMUST00000173632.1
 Pla2g6



phospholipase A2, group VI



chr7_+_97453204 0.508 ENSMUST00000050732.7
ENSMUST00000121987.1
 Kctd14

potassium channel tetramerisation domain containing 14

chr10_-_53638269 0.507 ENSMUST00000164393.1
 Fam184a
family with sequence similarity 184, member A
chr1_+_135729147 0.471 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr4_-_117125618 0.438 ENSMUST00000183310.1
 Btbd19
BTB (POZ) domain containing 19
chr15_-_79328154 0.434 ENSMUST00000166977.2
 Pla2g6
phospholipase A2, group VI
chr7_+_114768736 0.429 ENSMUST00000117543.1
 Insc
inscuteable homolog (Drosophila)
chr2_+_154548888 0.412 ENSMUST00000045116.4
ENSMUST00000109709.3
 1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr16_-_37384940 0.392 ENSMUST00000114781.1
ENSMUST00000114780.1
 Stxbp5l

syntaxin binding protein 5-like

chr19_-_5845471 0.386 ENSMUST00000174287.1
ENSMUST00000173672.1
 Neat1

nuclear paraspeckle assembly transcript 1 (non-protein coding)

chr2_+_102658640 0.383 ENSMUST00000080210.3
 Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr5_-_124327883 0.373 ENSMUST00000031344.6
 Mphosph9
M-phase phosphoprotein 9
chr14_-_72602945 0.372 ENSMUST00000162825.1
 Fndc3a
fibronectin type III domain containing 3A
chrX_-_102644210 0.363 ENSMUST00000052012.7
ENSMUST00000043596.5
ENSMUST00000119229.1
ENSMUST00000122022.1
ENSMUST00000120270.1
ENSMUST00000113611.2
 Phka1





phosphorylase kinase alpha 1





chr16_-_37384915 0.351 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
 Stxbp5l



syntaxin binding protein 5-like



chr16_+_96205719 0.337 ENSMUST00000129904.1
 Sh3bgr
SH3-binding domain glutamic acid-rich protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.0 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.2 0.8 GO:0055099 regulation of Cdc42 protein signal transduction(GO:0032489) response to high density lipoprotein particle(GO:0055099) platelet dense granule organization(GO:0060155)
0.0 0.8 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.0 0.7 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.2 0.5 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.5 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.1 0.5 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.1 0.4 GO:0089711 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) L-glutamate transmembrane transport(GO:0089711)
0.0 0.4 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.4 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707) resolution of recombination intermediates(GO:0071139)
0.1 0.3 GO:0002934 desmosome organization(GO:0002934)
0.0 0.3 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.2 GO:0014891 striated muscle atrophy(GO:0014891)
0.1 0.2 GO:0006558 L-phenylalanine metabolic process(GO:0006558) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221)
0.1 0.2 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.2 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.2 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:0030673 axolemma(GO:0030673)
0.1 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.3 GO:0031523 Myb complex(GO:0031523)
0.1 0.2 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.3 0.8 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.2 0.5 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.2 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.2 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0044653 trehalase activity(GO:0015927) dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859)
0.0 0.1 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)