Motif ID: Nr1h4

Z-value: 0.769


Transcription factors associated with Nr1h4:

Gene SymbolEntrez IDGene Name
Nr1h4 ENSMUSG00000047638.9 Nr1h4



Activity profile for motif Nr1h4.

activity profile for motif Nr1h4


Sorted Z-values histogram for motif Nr1h4

Sorted Z-values for motif Nr1h4



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr1h4

PNG image of the network

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Top targets:


Showing 1 to 20 of 130 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_94179089 2.317 ENSMUST00000034215.6
Mt1
metallothionein 1
chr4_+_117849361 2.150 ENSMUST00000163288.1
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr4_+_117849193 2.105 ENSMUST00000132043.2
ENSMUST00000169990.1
Slc6a9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr7_-_99695809 1.983 ENSMUST00000107086.2
Slco2b1
solute carrier organic anion transporter family, member 2b1
chr7_-_31055594 1.903 ENSMUST00000039909.6
Fxyd1
FXYD domain-containing ion transport regulator 1
chr5_-_147725988 1.812 ENSMUST00000110529.1
ENSMUST00000031652.3
ENSMUST00000031653.5
Flt1


FMS-like tyrosine kinase 1


chr7_-_44670820 1.623 ENSMUST00000048102.7
Myh14
myosin, heavy polypeptide 14
chr11_-_3931960 1.510 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
Tcn2




transcobalamin 2




chr5_-_113800356 1.262 ENSMUST00000160374.1
ENSMUST00000067853.5
Tmem119

transmembrane protein 119

chr19_+_5474681 1.251 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr5_-_116422858 1.249 ENSMUST00000036991.4
Hspb8
heat shock protein 8
chr9_+_44107268 1.185 ENSMUST00000114821.2
ENSMUST00000114818.2
C1qtnf5

C1q and tumor necrosis factor related protein 5

chr17_-_21933022 1.170 ENSMUST00000074295.7
Zfp942
zinc finger protein 942
chrX_-_18461371 1.107 ENSMUST00000044188.4
4930578C19Rik
RIKEN cDNA 4930578C19 gene
chr11_-_3931789 1.086 ENSMUST00000109992.1
ENSMUST00000109988.1
Tcn2

transcobalamin 2

chr14_-_26170283 1.066 ENSMUST00000100809.4
Plac9b
placenta specific 9b
chr16_-_20730544 1.031 ENSMUST00000076422.5
Thpo
thrombopoietin
chr9_-_32541589 0.909 ENSMUST00000016231.7
Fli1
Friend leukemia integration 1
chr9_+_44107286 0.890 ENSMUST00000152956.1
ENSMUST00000114815.1
C1qtnf5

C1q and tumor necrosis factor related protein 5

chr16_-_29962307 0.874 ENSMUST00000100016.3
Gm1968
predicted gene 1968

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 4.3 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 2.7 GO:0070206 protein trimerization(GO:0070206)
0.9 2.6 GO:0015889 cobalamin transport(GO:0015889)
0.3 2.3 GO:0010273 detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169)
0.2 2.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.6 1.9 GO:1903795 regulation of inorganic anion transmembrane transport(GO:1903795)
0.3 1.8 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 1.6 GO:0071625 vocalization behavior(GO:0071625)
0.0 1.6 GO:0007605 sensory perception of sound(GO:0007605)
0.3 1.3 GO:1903012 positive regulation of bone development(GO:1903012)
0.3 1.0 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.9 GO:0035855 megakaryocyte development(GO:0035855)
0.3 0.8 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.1 0.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.8 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.2 0.7 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.0 0.7 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.2 0.6 GO:0043465 regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003)
0.2 0.6 GO:1903525 regulation of membrane tubulation(GO:1903525)

Gene overrepresentation in cellular_component category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.6 GO:0098793 presynapse(GO:0098793)
0.0 3.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 2.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.9 GO:0034707 chloride channel complex(GO:0034707)
0.3 1.6 GO:0097513 myosin II filament(GO:0097513)
0.3 0.8 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.8 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.8 GO:0005876 spindle microtubule(GO:0005876)
0.1 0.7 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.4 GO:1990879 CST complex(GO:1990879)
0.1 0.4 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.1 0.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 4.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.4 2.6 GO:0031419 cobalamin binding(GO:0031419)
0.0 2.3 GO:0005507 copper ion binding(GO:0005507)
0.3 2.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 1.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.3 1.8 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.0 GO:0005179 hormone activity(GO:0005179)
0.3 0.8 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.8 GO:0005080 protein kinase C binding(GO:0005080)
0.2 0.7 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.7 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.5 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.4 GO:0050897 cobalt ion binding(GO:0050897)
0.1 0.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.4 GO:0034711 inhibin binding(GO:0034711)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)