Motif ID: Nr1i3

Z-value: 1.719


Transcription factors associated with Nr1i3:

Gene SymbolEntrez IDGene Name
Nr1i3 ENSMUSG00000005677.8 Nr1i3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr1i3mm10_v2_chr1_+_171213969_1712140070.048.9e-01Click!


Activity profile for motif Nr1i3.

activity profile for motif Nr1i3


Sorted Z-values histogram for motif Nr1i3

Sorted Z-values for motif Nr1i3



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr1i3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_25469742 9.375 ENSMUST00000114259.2
ENSMUST00000015234.6
 Ptgds

prostaglandin D2 synthase (brain)

chr16_+_91269759 6.880 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr10_-_102490418 6.228 ENSMUST00000020040.3
 Nts
neurotensin
chr4_-_136892867 5.884 ENSMUST00000046332.5
 C1qc
complement component 1, q subcomponent, C chain
chr2_-_25470031 4.793 ENSMUST00000114251.1
 Ptgds
prostaglandin D2 synthase (brain)
chr1_-_171059390 4.277 ENSMUST00000164044.1
ENSMUST00000169017.1
 Fcgr3

Fc receptor, IgG, low affinity III

chr8_+_57455898 4.134 ENSMUST00000034023.3
 Scrg1
scrapie responsive gene 1
chr6_+_90550789 3.493 ENSMUST00000130418.1
ENSMUST00000032175.8
 Aldh1l1

aldehyde dehydrogenase 1 family, member L1

chr10_+_61171954 3.084 ENSMUST00000122261.1
ENSMUST00000121297.1
ENSMUST00000035894.5
 Tbata


thymus, brain and testes associated


chr1_-_140183404 3.081 ENSMUST00000066859.6
ENSMUST00000111976.2
 Cfh

complement component factor h

chr18_+_65873478 2.860 ENSMUST00000025395.8
ENSMUST00000173530.1
 Grp

gastrin releasing peptide

chr9_-_121495678 2.830 ENSMUST00000035120.4
 Cck
cholecystokinin
chr3_+_66219909 2.806 ENSMUST00000029421.5
 Ptx3
pentraxin related gene
chrX_+_10485121 2.754 ENSMUST00000076354.6
ENSMUST00000115526.1
 Tspan7

tetraspanin 7

chr10_+_57794335 2.710 ENSMUST00000151623.1
ENSMUST00000020022.7
 Smpdl3a

sphingomyelin phosphodiesterase, acid-like 3A

chr6_-_60828889 2.605 ENSMUST00000114268.3
 Snca
synuclein, alpha
chr11_-_3931960 2.509 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
 Tcn2




transcobalamin 2




chr2_+_122147680 2.479 ENSMUST00000102476.4
 B2m
beta-2 microglobulin
chr4_-_128962420 2.445 ENSMUST00000119354.1
ENSMUST00000106068.1
ENSMUST00000030581.3
 Adc


arginine decarboxylase


chr7_-_66427469 2.371 ENSMUST00000015278.7
 Aldh1a3
aldehyde dehydrogenase family 1, subfamily A3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 584 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.9 14.7 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.2 7.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 6.2 GO:0048663 neuron fate commitment(GO:0048663)
0.8 5.9 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.6 4.6 GO:0097460 ferrous iron import into cell(GO:0097460)
1.4 4.3 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.1 4.3 GO:0008542 visual learning(GO:0008542)
1.1 4.2 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726) negative regulation of synaptic transmission, dopaminergic(GO:0032227) cellular response to copper ion(GO:0071280) regulation of peroxidase activity(GO:2000468)
1.3 4.0 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.6 3.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.6 3.7 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
1.2 3.6 GO:0008228 opsonization(GO:0008228)
1.2 3.5 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
1.2 3.5 GO:0015889 cobalamin transport(GO:0015889)
0.4 3.1 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)
0.3 2.8 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.2 2.7 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.1 2.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 2.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 2.5 GO:0006883 cellular sodium ion homeostasis(GO:0006883)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 227 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 14.8 GO:0005615 extracellular space(GO:0005615)
0.1 12.0 GO:0072562 blood microparticle(GO:0072562)
0.2 11.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 9.3 GO:0070469 respiratory chain(GO:0070469)
0.0 8.6 GO:0005667 transcription factor complex(GO:0005667)
0.1 7.0 GO:0005901 caveola(GO:0005901)
0.4 5.2 GO:0043203 axon hillock(GO:0043203)
0.0 4.9 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 4.8 GO:0044306 neuron projection terminus(GO:0044306)
0.5 4.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 4.4 GO:0016323 basolateral plasma membrane(GO:0016323)
1.1 4.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 4.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 3.3 GO:0019866 organelle inner membrane(GO:0019866)
0.0 3.2 GO:0005925 focal adhesion(GO:0005925)
0.3 3.1 GO:0070852 cell body fiber(GO:0070852)
0.1 3.1 GO:0005811 lipid particle(GO:0005811)
0.2 3.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.9 2.6 GO:0000802 transverse filament(GO:0000802)
0.0 2.6 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 380 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 14.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
3.5 14.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
1.7 5.2 GO:0001851 complement component C3b binding(GO:0001851)
0.0 4.7 GO:0003735 structural constituent of ribosome(GO:0003735)
1.4 4.3 GO:0019770 IgG receptor activity(GO:0019770)
0.7 4.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 3.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.5 3.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.4 3.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
1.2 3.5 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 3.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 3.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.0 3.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.4 3.1 GO:0031419 cobalamin binding(GO:0031419)
0.2 2.9 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.6 2.8 GO:0001849 complement component C1q binding(GO:0001849)
0.1 2.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 2.6 GO:0048018 receptor agonist activity(GO:0048018)
0.2 2.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 2.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)