Motif ID: Nr2c1

Z-value: 0.436


Transcription factors associated with Nr2c1:

Gene SymbolEntrez IDGene Name
Nr2c1 ENSMUSG00000005897.8 Nr2c1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2c1mm10_v2_chr10_+_94147982_941480230.156.1e-01Click!


Activity profile for motif Nr2c1.

activity profile for motif Nr2c1


Sorted Z-values histogram for motif Nr2c1

Sorted Z-values for motif Nr2c1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2c1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 125 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_107631322 0.849 ENSMUST00000106703.1
 Gm10961
predicted gene 10961
chr2_-_54085542 0.391 ENSMUST00000100089.2
 Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr13_-_9878998 0.364 ENSMUST00000063093.9
 Chrm3
cholinergic receptor, muscarinic 3, cardiac
chr1_+_133309778 0.343 ENSMUST00000094557.4
ENSMUST00000183457.1
ENSMUST00000183738.1
ENSMUST00000185157.1
ENSMUST00000184603.1
 Golt1a

Kiss1

GOLT1A
golgi transport 1 homolog A (S. cerevisiae)

KiSS-1 metastasis-suppressor

KISS1 isoform e
chr1_+_59256906 0.326 ENSMUST00000160662.1
ENSMUST00000114248.2
 Cdk15

cyclin-dependent kinase 15

chr3_+_96830069 0.304 ENSMUST00000058865.7
 Pdzk1
PDZ domain containing 1
chr15_-_89425795 0.303 ENSMUST00000168376.1
 Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr7_+_45896941 0.296 ENSMUST00000069772.7
ENSMUST00000107716.1
 Tmem143

transmembrane protein 143

chr12_+_61523889 0.272 ENSMUST00000119481.1
ENSMUST00000055815.7
 Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr16_-_4523056 0.252 ENSMUST00000090500.3
ENSMUST00000023161.7
 Srl

sarcalumenin

chr2_-_112480817 0.240 ENSMUST00000099589.2
 Chrm5
cholinergic receptor, muscarinic 5
chr2_+_164805082 0.236 ENSMUST00000052107.4
 Zswim3
zinc finger SWIM-type containing 3
chr4_+_117251951 0.226 ENSMUST00000062824.5
 Tmem53
transmembrane protein 53
chr11_+_75193783 0.220 ENSMUST00000102514.3
 Rtn4rl1
reticulon 4 receptor-like 1
chr4_+_117252010 0.216 ENSMUST00000125943.1
ENSMUST00000106434.1
 Tmem53

transmembrane protein 53

chr13_-_73328442 0.197 ENSMUST00000022097.5
 Ndufs6
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr19_+_46152505 0.197 ENSMUST00000026254.7
 Gbf1
golgi-specific brefeldin A-resistance factor 1
chr4_+_150853919 0.194 ENSMUST00000073600.2
 Errfi1
ERBB receptor feedback inhibitor 1
chr7_+_45897429 0.193 ENSMUST00000140243.1
 Tmem143
transmembrane protein 143
chr8_-_123894736 0.189 ENSMUST00000034453.4
 Acta1
actin, alpha 1, skeletal muscle

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.6 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.3 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.1 0.3 GO:0032275 luteinizing hormone secretion(GO:0032275) positive regulation of gonadotropin secretion(GO:0032278)
0.1 0.3 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.1 0.3 GO:0015879 carnitine transport(GO:0015879)
0.1 0.2 GO:0070973 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.2 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.0 0.1 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.0 0.1 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 0.1 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.4 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.1 GO:0002177 manchette(GO:0002177)

Gene overrepresentation in molecular_function category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.5 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 0.3 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 0.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.2 GO:0048045 4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)