Motif ID: Nr2c2

Z-value: 1.106


Transcription factors associated with Nr2c2:

Gene SymbolEntrez IDGene Name
Nr2c2 ENSMUSG00000005893.8 Nr2c2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2c2mm10_v2_chr6_+_92092369_92092433-0.602.5e-02Click!


Activity profile for motif Nr2c2.

activity profile for motif Nr2c2


Sorted Z-values histogram for motif Nr2c2

Sorted Z-values for motif Nr2c2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2c2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_79500081 1.661 ENSMUST00000181511.2
ENSMUST00000182937.1
 AI854517

expressed sequence AI854517

chr7_+_79500018 1.619 ENSMUST00000182495.1
ENSMUST00000183043.1
 AI854517

expressed sequence AI854517

chr11_+_61485431 1.588 ENSMUST00000064783.3
ENSMUST00000040522.6
 Mfap4

microfibrillar-associated protein 4

chr7_-_99695809 1.550 ENSMUST00000107086.2
 Slco2b1
solute carrier organic anion transporter family, member 2b1
chr10_-_79983970 1.474 ENSMUST00000124536.1
 Tmem259
transmembrane protein 259
chr10_-_79984227 1.357 ENSMUST00000052885.7
 Tmem259
transmembrane protein 259
chr19_+_8929628 1.305 ENSMUST00000096241.4
 Eml3
echinoderm microtubule associated protein like 3
chr14_-_52020698 1.265 ENSMUST00000067549.7
 Zfp219
zinc finger protein 219
chr9_-_124424154 1.199 ENSMUST00000180270.1
 Ppp2r3d
protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta
chr3_+_118433797 1.196 ENSMUST00000180593.1
ENSMUST00000181926.1
ENSMUST00000181060.1
ENSMUST00000181310.1
 Gm26871



predicted gene, 26871



chr11_+_116593687 1.188 ENSMUST00000153476.1
 Aanat
arylalkylamine N-acetyltransferase
chr8_-_71537402 1.116 ENSMUST00000051672.7
 Bst2
bone marrow stromal cell antigen 2
chr13_-_24761861 1.093 ENSMUST00000006898.3
ENSMUST00000110382.2
 Gmnn

geminin

chr14_+_65806066 1.068 ENSMUST00000139644.1
 Pbk
PDZ binding kinase
chr19_-_8929323 0.979 ENSMUST00000096242.3
 Rom1
rod outer segment membrane protein 1
chr3_-_115888086 0.967 ENSMUST00000067500.5
 A930005H10Rik
RIKEN cDNA A930005H10 gene
chr8_+_4248188 0.945 ENSMUST00000110993.1
 Gm14378
predicted gene 14378
chr1_+_195017399 0.939 ENSMUST00000181273.1
 A330023F24Rik
RIKEN cDNA A330023F24 gene
chr4_-_97778042 0.902 ENSMUST00000146447.1
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr17_-_56717681 0.901 ENSMUST00000164907.1
 Vmac
vimentin-type intermediate filament associated coiled-coil protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 191 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.4 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.2 2.0 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.6 1.9 GO:0030421 defecation(GO:0030421)
0.0 1.8 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 1.7 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 1.7 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.2 1.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 1.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 1.6 GO:0060074 synapse maturation(GO:0060074)
0.0 1.5 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.3 1.3 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.1 1.2 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)
0.0 1.2 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.3 1.1 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.0 1.1 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 1.0 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 1.0 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.3 0.9 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.9 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 76 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 2.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.5 1.6 GO:0071953 elastic fiber(GO:0071953)
0.0 1.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.3 0.9 GO:0014802 terminal cisterna(GO:0014802)
0.2 0.9 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.8 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.8 GO:0061574 ASAP complex(GO:0061574)
0.1 0.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 0.7 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 0.6 GO:1990879 CST complex(GO:1990879)
0.1 0.6 GO:0031314 mitochondrial inner membrane presequence translocase complex(GO:0005744) extrinsic component of mitochondrial inner membrane(GO:0031314)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 125 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.4 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 2.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.2 1.6 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 1.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.3 1.3 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 1.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 1.2 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.1 1.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 1.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 0.9 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 0.9 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.9 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)