Motif ID: Nr2e1

Z-value: 0.540


Transcription factors associated with Nr2e1:

Gene SymbolEntrez IDGene Name
Nr2e1 ENSMUSG00000019803.5 Nr2e1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2e1mm10_v2_chr10_-_42583628_425836390.175.6e-01Click!


Activity profile for motif Nr2e1.

activity profile for motif Nr2e1


Sorted Z-values histogram for motif Nr2e1

Sorted Z-values for motif Nr2e1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2e1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_36489191 2.324 ENSMUST00000171777.1
6430573F11Rik
RIKEN cDNA 6430573F11 gene
chr4_+_32238950 2.026 ENSMUST00000037416.6
Bach2
BTB and CNC homology 2
chr3_+_26331150 1.743 ENSMUST00000099182.2
A830092H15Rik
RIKEN cDNA A830092H15 gene
chr4_+_28813152 0.686 ENSMUST00000108194.2
ENSMUST00000108191.1
Epha7

Eph receptor A7

chr4_+_28813125 0.649 ENSMUST00000029964.5
ENSMUST00000080934.4
Epha7

Eph receptor A7

chr14_+_32028989 0.628 ENSMUST00000022460.4
Galnt15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr7_+_78895903 0.478 ENSMUST00000107425.1
ENSMUST00000107421.1
ENSMUST00000107423.1
Aen


apoptosis enhancing nuclease


chr4_-_35845204 0.476 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chr12_+_111166485 0.423 ENSMUST00000139162.1
Traf3
TNF receptor-associated factor 3
chr4_-_63403330 0.370 ENSMUST00000035724.4
Akna
AT-hook transcription factor
chr15_+_41830921 0.349 ENSMUST00000166917.1
Oxr1
oxidation resistance 1
chr15_-_10485385 0.333 ENSMUST00000168690.1
Brix1
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chrX_-_139998519 0.324 ENSMUST00000113007.1
ENSMUST00000033810.7
ENSMUST00000113011.2
ENSMUST00000087400.5
Rbm41



RNA binding motif protein 41



chr10_+_18469958 0.320 ENSMUST00000162891.1
ENSMUST00000100054.3
Nhsl1

NHS-like 1

chr4_-_119415494 0.287 ENSMUST00000063642.2
Ccdc30
coiled-coil domain containing 30
chr6_+_126939957 0.264 ENSMUST00000032497.3
D6Wsu163e
DNA segment, Chr 6, Wayne State University 163, expressed
chrX_-_95658379 0.254 ENSMUST00000119640.1
Zc4h2
zinc finger, C4H2 domain containing
chrX_-_95658392 0.254 ENSMUST00000120620.1
Zc4h2
zinc finger, C4H2 domain containing
chr15_-_10485890 0.254 ENSMUST00000169050.1
ENSMUST00000022855.5
Brix1

BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)

chr10_-_61784014 0.215 ENSMUST00000020283.4
H2afy2
H2A histone family, member Y2
chrX_-_95658416 0.209 ENSMUST00000044382.6
Zc4h2
zinc finger, C4H2 domain containing
chr12_+_111166413 0.204 ENSMUST00000021706.4
Traf3
TNF receptor-associated factor 3
chr15_+_10486008 0.183 ENSMUST00000022856.8
ENSMUST00000100775.3
ENSMUST00000169519.1
Rad1


RAD1 homolog (S. pombe)


chr9_-_71163224 0.156 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr15_-_97705787 0.154 ENSMUST00000023104.5
Rpap3
RNA polymerase II associated protein 3
chr12_+_111166349 0.149 ENSMUST00000117269.1
Traf3
TNF receptor-associated factor 3
chr18_+_34840575 0.114 ENSMUST00000043484.7
Reep2
receptor accessory protein 2
chr2_-_73386396 0.109 ENSMUST00000112044.1
ENSMUST00000112043.1
ENSMUST00000076463.5
Gpr155


G protein-coupled receptor 155


chr12_+_111166536 0.096 ENSMUST00000060274.6
Traf3
TNF receptor-associated factor 3
chr18_+_36793918 0.094 ENSMUST00000001419.8
Zmat2
zinc finger, matrin type 2
chr14_-_54517353 0.079 ENSMUST00000023873.5
Prmt5
protein arginine N-methyltransferase 5
chr4_+_33924632 0.055 ENSMUST00000057188.6
Cnr1
cannabinoid receptor 1 (brain)
chr8_-_61902669 0.014 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr7_-_80405425 0.009 ENSMUST00000107362.3
ENSMUST00000135306.1
Furin

furin (paired basic amino acid cleaving enzyme)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 0.9 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.2 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.0 0.1 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.0 0.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.2 GO:0032782 urea transport(GO:0015840) bile acid secretion(GO:0032782) urea transmembrane transport(GO:0071918)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 2.3 GO:0008033 tRNA processing(GO:0008033)
0.0 0.1 GO:0060161 peptidyl-arginine omega-N-methylation(GO:0035247) histone H4-R3 methylation(GO:0043985) positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.1 GO:0031622 positive regulation of fever generation(GO:0031622)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 2.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 1.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 1.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.9 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 2.4 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.0 0.2 GO:0015265 urea channel activity(GO:0015265)