Motif ID: Nr2e3

Z-value: 0.944


Transcription factors associated with Nr2e3:

Gene SymbolEntrez IDGene Name
Nr2e3 ENSMUSG00000032292.2 Nr2e3



Activity profile for motif Nr2e3.

activity profile for motif Nr2e3


Sorted Z-values histogram for motif Nr2e3

Sorted Z-values for motif Nr2e3



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2e3

PNG image of the network

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Top targets:


Showing 1 to 20 of 169 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_72986716 2.776 ENSMUST00000112062.1
 Gm11084
predicted gene 11084
chr1_+_143640664 1.531 ENSMUST00000038252.2
 B3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr12_+_95695350 1.396 ENSMUST00000110117.1
 Flrt2
fibronectin leucine rich transmembrane protein 2
chr10_-_109009055 1.344 ENSMUST00000156979.1
 Syt1
synaptotagmin I
chr10_-_109010955 1.293 ENSMUST00000105276.1
ENSMUST00000064054.7
 Syt1

synaptotagmin I

chr7_+_36698002 1.173 ENSMUST00000021641.6
 Tshz3
teashirt zinc finger family member 3
chr2_-_140671440 1.167 ENSMUST00000099301.1
 Flrt3
fibronectin leucine rich transmembrane protein 3
chr2_+_65620829 1.129 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr9_-_16378231 1.035 ENSMUST00000082170.5
 Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr2_+_96318014 1.007 ENSMUST00000135431.1
ENSMUST00000162807.2
 Lrrc4c

leucine rich repeat containing 4C

chrX_-_143933089 1.004 ENSMUST00000087313.3
 Dcx
doublecortin
chr6_+_104492790 0.998 ENSMUST00000161446.1
ENSMUST00000161070.1
ENSMUST00000089215.5
 Cntn6


contactin 6


chr2_-_45112890 0.958 ENSMUST00000076836.6
 Zeb2
zinc finger E-box binding homeobox 2
chr18_-_35215008 0.946 ENSMUST00000091636.3
 Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr10_-_29144194 0.938 ENSMUST00000070359.2
 Gm9996
predicted gene 9996
chr5_+_76809964 0.891 ENSMUST00000120818.1
 C530008M17Rik
RIKEN cDNA C530008M17 gene
chr2_-_140671400 0.844 ENSMUST00000056760.3
 Flrt3
fibronectin leucine rich transmembrane protein 3
chr11_-_42182924 0.835 ENSMUST00000020707.5
ENSMUST00000132971.1
 Gabra1

gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1

chrX_+_120290259 0.829 ENSMUST00000113358.3
ENSMUST00000050239.9
ENSMUST00000113364.3
 Pcdh11x


protocadherin 11 X-linked


chr10_+_90576570 0.809 ENSMUST00000182786.1
ENSMUST00000182600.1
 Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 63 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.0 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.3 2.8 GO:0005513 detection of calcium ion(GO:0005513)
0.9 2.7 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.1 1.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 1.5 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 1.5 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.4 1.3 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.2 1.3 GO:2000809 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
0.3 1.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.2 1.0 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 1.0 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 1.0 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 1.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.9 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.2 0.8 GO:0086013 membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.0 0.8 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.8 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 0.7 GO:2000224 testosterone biosynthetic process(GO:0061370) regulation of testosterone biosynthetic process(GO:2000224)
0.1 0.7 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 2.7 GO:0044295 axonal growth cone(GO:0044295)
0.2 2.6 GO:0031045 dense core granule(GO:0031045)
0.2 1.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.3 1.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.1 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 0.8 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.7 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.6 GO:0097440 apical dendrite(GO:0097440)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.2 0.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.5 GO:0001740 Barr body(GO:0001740)
0.0 0.5 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.5 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1 0.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.4 GO:0005861 troponin complex(GO:0005861)
0.1 0.4 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.1 0.4 GO:0071437 invadopodium(GO:0071437)
0.1 0.3 GO:0097427 microtubule bundle(GO:0097427)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 3.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 2.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 2.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 1.5 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 1.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 1.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 1.3 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 1.1 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 1.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 0.8 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 0.7 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.7 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.6 GO:0050786 arachidonic acid binding(GO:0050544) RAGE receptor binding(GO:0050786)
0.1 0.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.6 GO:0005355 glucose transmembrane transporter activity(GO:0005355)