Motif ID: Nr2f1_Nr4a1

Z-value: 0.803

Transcription factors associated with Nr2f1_Nr4a1:

Gene SymbolEntrez IDGene Name
Nr2f1 ENSMUSG00000069171.7 Nr2f1
Nr4a1 ENSMUSG00000023034.6 Nr4a1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr4a1mm10_v2_chr15_+_101266839_101266859-0.204.9e-01Click!
Nr2f1mm10_v2_chr13_-_78199757_781998550.175.5e-01Click!


Activity profile for motif Nr2f1_Nr4a1.

activity profile for motif Nr2f1_Nr4a1


Sorted Z-values histogram for motif Nr2f1_Nr4a1

Sorted Z-values for motif Nr2f1_Nr4a1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2f1_Nr4a1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_79716588 2.023 ENSMUST00000099513.1
ENSMUST00000020581.2
 Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr2_-_60963192 1.559 ENSMUST00000028347.6
 Rbms1
RNA binding motif, single stranded interacting protein 1
chr6_+_90550789 1.377 ENSMUST00000130418.1
ENSMUST00000032175.8
 Aldh1l1

aldehyde dehydrogenase 1 family, member L1

chrX_+_10485121 1.292 ENSMUST00000076354.6
ENSMUST00000115526.1
 Tspan7

tetraspanin 7

chr3_+_114030532 1.274 ENSMUST00000123619.1
ENSMUST00000092155.5
 Col11a1

collagen, type XI, alpha 1

chr6_-_119544282 1.110 ENSMUST00000119369.1
ENSMUST00000178696.1
 Wnt5b

wingless-related MMTV integration site 5B

chr16_-_20730544 1.086 ENSMUST00000076422.5
 Thpo
thrombopoietin
chr6_-_137571007 0.948 ENSMUST00000100841.2
 Eps8
epidermal growth factor receptor pathway substrate 8
chr9_-_107668967 0.944 ENSMUST00000177567.1
 Slc38a3
solute carrier family 38, member 3
chr11_-_70656467 0.910 ENSMUST00000131642.1
 Gm12319
predicted gene 12319
chr1_-_164458345 0.909 ENSMUST00000027863.7
 Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr3_-_58885212 0.892 ENSMUST00000055636.6
ENSMUST00000072551.6
ENSMUST00000051408.7
 Clrn1


clarin 1


chr4_+_154960915 0.857 ENSMUST00000049621.6
 Hes5
hairy and enhancer of split 5 (Drosophila)
chr7_-_4522427 0.855 ENSMUST00000098859.3
 Tnni3
troponin I, cardiac 3
chr11_-_3504766 0.843 ENSMUST00000044507.5
 Inpp5j
inositol polyphosphate 5-phosphatase J
chr19_+_8591254 0.831 ENSMUST00000010251.3
ENSMUST00000170817.1
 Slc22a8

solute carrier family 22 (organic anion transporter), member 8

chr13_-_92131494 0.816 ENSMUST00000099326.3
ENSMUST00000146492.1
 Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chr5_+_63649335 0.804 ENSMUST00000159584.1
 3110047P20Rik
RIKEN cDNA 3110047P20 gene
chr17_+_17831298 0.802 ENSMUST00000150302.1
 4930546H06Rik
RIKEN cDNA 4930546H06 gene
chr2_+_130576170 0.789 ENSMUST00000028764.5
 Oxt
oxytocin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 202 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.0 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.5 1.6 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.5 1.4 GO:1903795 regulation of inorganic anion transmembrane transport(GO:1903795)
0.5 1.4 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.2 1.4 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.2 1.3 GO:0035989 tendon development(GO:0035989)
0.0 1.3 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.3 1.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.3 1.0 GO:0042822 vitamin B6 metabolic process(GO:0042816) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 1.0 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2 0.9 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 0.9 GO:0006867 asparagine transport(GO:0006867) glutamine transport(GO:0006868)
0.2 0.9 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.9 GO:0050957 equilibrioception(GO:0050957)
0.1 0.9 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.3 0.8 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.3 0.8 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.3 0.8 GO:0042713 sperm ejaculation(GO:0042713)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 70 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 2.8 GO:0098803 respiratory chain complex(GO:0098803)
0.1 2.2 GO:0032590 dendrite membrane(GO:0032590)
0.2 1.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 1.4 GO:0005861 troponin complex(GO:0005861)
0.1 1.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 1.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.1 GO:0005814 centriole(GO:0005814)
0.1 1.0 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 1.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.0 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.2 0.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.7 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.6 GO:0031902 late endosome membrane(GO:0031902)
0.2 0.5 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.5 GO:0071439 clathrin complex(GO:0071439)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 127 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.2 1.8 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 1.8 GO:0005109 frizzled binding(GO:0005109)
0.0 1.5 GO:0005179 hormone activity(GO:0005179)
0.5 1.4 GO:0030172 troponin C binding(GO:0030172)
0.5 1.4 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 1.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 1.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 1.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.3 1.0 GO:0031403 lithium ion binding(GO:0031403)
0.0 1.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 0.9 GO:0001851 complement component C3b binding(GO:0001851)
0.2 0.9 GO:0015186 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.9 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 0.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.3 0.8 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)