Motif ID: Nr2f2

Z-value: 0.597


Transcription factors associated with Nr2f2:

Gene SymbolEntrez IDGene Name
Nr2f2 ENSMUSG00000030551.7 Nr2f2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2f2mm10_v2_chr7_-_70366735_703667710.107.4e-01Click!


Activity profile for motif Nr2f2.

activity profile for motif Nr2f2


Sorted Z-values histogram for motif Nr2f2

Sorted Z-values for motif Nr2f2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2f2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_29984219 0.951 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr5_+_124194894 0.560 ENSMUST00000159053.1
ENSMUST00000162577.1
Gm16338

predicted gene 16338

chrX_+_42067876 0.508 ENSMUST00000126375.1
Xiap
X-linked inhibitor of apoptosis
chr2_+_130406478 0.450 ENSMUST00000055421.4
Tmem239
transmembrane 239
chr3_-_94412883 0.412 ENSMUST00000181305.1
1700040D17Rik
RIKEN cDNA 1700040D17 gene
chr5_-_45857473 0.407 ENSMUST00000016026.7
ENSMUST00000067997.6
ENSMUST00000045586.6
Lcorl


ligand dependent nuclear receptor corepressor-like


chr5_-_107869153 0.405 ENSMUST00000128723.1
ENSMUST00000124034.1
Evi5

ecotropic viral integration site 5

chr19_-_10482874 0.400 ENSMUST00000038842.3
Ppp1r32
protein phosphatase 1, regulatory subunit 32
chrX_+_42067836 0.374 ENSMUST00000115094.1
Xiap
X-linked inhibitor of apoptosis
chr12_+_16894894 0.352 ENSMUST00000020904.6
Rock2
Rho-associated coiled-coil containing protein kinase 2
chr16_+_84835070 0.348 ENSMUST00000009120.7
Gabpa
GA repeat binding protein, alpha
chr3_+_157534103 0.348 ENSMUST00000106058.1
Zranb2
zinc finger, RAN-binding domain containing 2
chr3_-_116712198 0.331 ENSMUST00000120120.1
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr17_+_17831004 0.319 ENSMUST00000172097.2
4930546H06Rik
RIKEN cDNA 4930546H06 gene
chr14_-_102982630 0.307 ENSMUST00000184744.1
KCTD12
mmu-mir-5130
chr1_+_6214627 0.301 ENSMUST00000027040.6
Rb1cc1
RB1-inducible coiled-coil 1
chr17_+_21555046 0.301 ENSMUST00000079242.3
Zfp52
zinc finger protein 52
chr7_-_135716374 0.300 ENSMUST00000033310.7
Mki67
antigen identified by monoclonal antibody Ki 67
chr19_-_23273893 0.297 ENSMUST00000087556.5
Smc5
structural maintenance of chromosomes 5
chr8_+_40307458 0.296 ENSMUST00000068999.7
Micu3
mitochondrial calcium uptake family, member 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 80 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.0 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.3 0.9 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.6 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.5 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.4 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.0 0.4 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.3 GO:1990705 cholangiocyte proliferation(GO:1990705)
0.1 0.3 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 0.3 GO:0071139 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) resolution of recombination intermediates(GO:0071139)
0.1 0.3 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.3 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.2 GO:0048296 isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.1 0.2 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.1 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.4 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 0.4 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.3 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0001652 granular component(GO:0001652)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0000346 transcription export complex(GO:0000346)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.4 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.4 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.4 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.4 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)
0.1 0.3 GO:0019002 GMP binding(GO:0019002)
0.0 0.3 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.2 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0031686 A1 adenosine receptor binding(GO:0031686)