Motif ID: Nr2f6

Z-value: 0.594


Transcription factors associated with Nr2f6:

Gene SymbolEntrez IDGene Name
Nr2f6 ENSMUSG00000002393.8 Nr2f6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2f6mm10_v2_chr8_-_71381907_71381977-0.214.7e-01Click!


Activity profile for motif Nr2f6.

activity profile for motif Nr2f6


Sorted Z-values histogram for motif Nr2f6

Sorted Z-values for motif Nr2f6



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2f6

PNG image of the network

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Top targets:


Showing 1 to 20 of 130 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_121967822 1.939 ENSMUST00000137089.1
 Arhgap29
Rho GTPase activating protein 29
chr2_+_164805082 1.166 ENSMUST00000052107.4
 Zswim3
zinc finger SWIM-type containing 3
chr4_+_85205120 1.158 ENSMUST00000107188.3
 Sh3gl2
SH3-domain GRB2-like 2
chr4_+_85205417 1.058 ENSMUST00000030212.8
ENSMUST00000107189.1
ENSMUST00000107184.1
 Sh3gl2


SH3-domain GRB2-like 2


chr11_+_32283511 0.968 ENSMUST00000093209.3
 Hba-a1
hemoglobin alpha, adult chain 1
chr5_-_24902315 0.899 ENSMUST00000131486.1
 Prkag2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr9_+_109051153 0.870 ENSMUST00000155541.1
ENSMUST00000120305.1
ENSMUST00000154113.1
ENSMUST00000128976.1
ENSMUST00000135942.1
ENSMUST00000143754.1
 Shisa5





shisa homolog 5 (Xenopus laevis)





chr4_-_97778042 0.738 ENSMUST00000146447.1
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr2_+_158028687 0.730 ENSMUST00000109518.1
ENSMUST00000029180.7
 Rprd1b

regulation of nuclear pre-mRNA domain containing 1B

chr2_+_158028733 0.726 ENSMUST00000152452.1
 Rprd1b
regulation of nuclear pre-mRNA domain containing 1B
chr2_+_158028481 0.689 ENSMUST00000103123.3
 Rprd1b
regulation of nuclear pre-mRNA domain containing 1B
chr6_+_86365673 0.675 ENSMUST00000071492.7
 Fam136a
family with sequence similarity 136, member A
chr10_-_35711891 0.663 ENSMUST00000080898.2
 Amd2
S-adenosylmethionine decarboxylase 2
chr7_+_38183217 0.645 ENSMUST00000165308.1
 1600014C10Rik
RIKEN cDNA 1600014C10 gene
chr5_-_137741601 0.614 ENSMUST00000119498.1
ENSMUST00000061789.7
 Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr16_+_4684070 0.614 ENSMUST00000060067.5
ENSMUST00000115854.3
 Dnaja3

DnaJ (Hsp40) homolog, subfamily A, member 3

chr13_-_73328442 0.587 ENSMUST00000022097.5
 Ndufs6
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr4_-_137048695 0.579 ENSMUST00000049583.7
 Zbtb40
zinc finger and BTB domain containing 40
chr7_-_30232186 0.575 ENSMUST00000006254.5
 Tbcb
tubulin folding cofactor B
chr6_+_83156401 0.571 ENSMUST00000032106.4
 1700003E16Rik
RIKEN cDNA 1700003E16 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.2 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.2 2.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 1.0 GO:0048821 erythrocyte development(GO:0048821)
0.0 0.9 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.9 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.8 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.2 0.7 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.6 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 0.6 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.6 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.4 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.1 0.4 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.1 0.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.4 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.0 0.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.4 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.3 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.2 1.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.9 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 0.6 GO:1990879 CST complex(GO:1990879)
0.1 0.6 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.1 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.5 GO:0031314 mitochondrial inner membrane presequence translocase complex(GO:0005744) extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.5 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.5 GO:0016460 myosin II complex(GO:0016460)
0.1 0.4 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 0.4 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.3 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.2 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.2 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.2 1.0 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.9 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 0.9 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 0.7 GO:0019808 polyamine binding(GO:0019808)
0.1 0.6 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.6 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.1 0.2 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.1 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.2 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)