Motif ID: Nr3c2

Z-value: 0.555


Transcription factors associated with Nr3c2:

Gene SymbolEntrez IDGene Name
Nr3c2 ENSMUSG00000031618.7 Nr3c2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr3c2mm10_v2_chr8_+_76902277_769024760.283.4e-01Click!


Activity profile for motif Nr3c2.

activity profile for motif Nr3c2


Sorted Z-values histogram for motif Nr3c2

Sorted Z-values for motif Nr3c2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr3c2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_6882068 2.393 ENSMUST00000142635.1
ENSMUST00000052609.8
 Dlx5

distal-less homeobox 5

chr8_+_94179089 2.233 ENSMUST00000034215.6
 Mt1
metallothionein 1
chr10_-_117282262 1.911 ENSMUST00000092163.7
 Lyz2
lysozyme 2
chr9_+_123366921 1.327 ENSMUST00000038863.7
 Lars2
leucyl-tRNA synthetase, mitochondrial
chr11_+_101448403 1.265 ENSMUST00000010502.6
 Ifi35
interferon-induced protein 35
chr10_+_26822560 1.129 ENSMUST00000135866.1
 Arhgap18
Rho GTPase activating protein 18
chr10_+_21993890 0.884 ENSMUST00000092673.4
 Sgk1
serum/glucocorticoid regulated kinase 1
chr3_-_95904683 0.616 ENSMUST00000147962.1
ENSMUST00000036181.8
 Car14

carbonic anhydrase 14

chr14_-_8309770 0.604 ENSMUST00000121887.1
ENSMUST00000036070.8
ENSMUST00000137133.1
 Fam107a


family with sequence similarity 107, member A


chr5_+_112288734 0.575 ENSMUST00000151947.1
 Tpst2
protein-tyrosine sulfotransferase 2
chr15_+_102102926 0.568 ENSMUST00000169627.1
ENSMUST00000046144.9
 Tenc1

tensin like C1 domain-containing phosphatase

chr14_+_70530819 0.491 ENSMUST00000047331.6
 Lgi3
leucine-rich repeat LGI family, member 3
chr1_-_74935549 0.457 ENSMUST00000094844.3
 Ccdc108
coiled-coil domain containing 108
chr16_-_96192222 0.425 ENSMUST00000113804.1
ENSMUST00000054855.7
 Lca5l

Leber congenital amaurosis 5-like

chr2_+_172472512 0.380 ENSMUST00000029007.2
 Fam209
family with sequence similarity 209
chr3_-_88739692 0.289 ENSMUST00000090946.2
 Gm10253
predicted gene 10253
chr8_+_71406003 0.251 ENSMUST00000119976.1
ENSMUST00000120725.1
 Ankle1

ankyrin repeat and LEM domain containing 1

chr5_+_31697665 0.247 ENSMUST00000080598.7
 Bre
brain and reproductive organ-expressed protein
chr8_+_70697739 0.205 ENSMUST00000095267.4
 Jund
Jun proto-oncogene related gene d
chr10_-_78464969 0.194 ENSMUST00000041616.8
 Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr10_+_128225830 0.176 ENSMUST00000026455.7
 Mip
major intrinsic protein of eye lens fiber
chr1_-_171240055 0.172 ENSMUST00000131286.1
 Ndufs2
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr15_-_82047579 0.163 ENSMUST00000166578.1
ENSMUST00000080622.7
 Nhp2l1

NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)

chr7_-_25390098 0.152 ENSMUST00000054301.7
 Lipe
lipase, hormone sensitive
chr10_-_78464853 0.139 ENSMUST00000105385.1
 Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr11_+_69098937 0.029 ENSMUST00000021271.7
 Per1
period circadian clock 1
chr10_-_14718191 0.024 ENSMUST00000020016.4
 Gje1
gap junction protein, epsilon 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0060166 olfactory pit development(GO:0060166)
0.3 2.2 GO:0010273 detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169)
0.2 0.6 GO:0060468 prevention of polyspermy(GO:0060468)
0.1 0.3 GO:0042822 vitamin B6 metabolic process(GO:0042816) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 1.9 GO:0019835 cytolysis(GO:0019835)
0.1 0.6 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.9 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 1.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.2 GO:0032782 cellular water homeostasis(GO:0009992) bile acid secretion(GO:0032782)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.2 GO:0001651 dense fibrillar component(GO:0001651)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.3 GO:0031403 lithium ion binding(GO:0031403)
0.1 0.9 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 2.4 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 2.1 GO:0005507 copper ion binding(GO:0005507)
0.0 0.2 GO:0034511 U4 snRNA binding(GO:0030621) U3 snoRNA binding(GO:0034511)
0.0 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.2 GO:0015168 glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
0.0 0.2 GO:0048038 quinone binding(GO:0048038)
0.0 1.9 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)