Motif ID: Nr4a3

Z-value: 0.675


Transcription factors associated with Nr4a3:

Gene SymbolEntrez IDGene Name
Nr4a3 ENSMUSG00000028341.3 Nr4a3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr4a3mm10_v2_chr4_+_48045144_48045160-0.165.9e-01Click!


Activity profile for motif Nr4a3.

activity profile for motif Nr4a3


Sorted Z-values histogram for motif Nr4a3

Sorted Z-values for motif Nr4a3



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr4a3

PNG image of the network

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Top targets:


Showing 1 to 20 of 96 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_-_1245685 2.136 ENSMUST00000143286.1
ENSMUST00000137048.1
ENSMUST00000069309.7
ENSMUST00000139365.1
Uty



ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome



chrY_-_1245753 1.173 ENSMUST00000154004.1
Uty
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr4_+_154960915 1.086 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr1_-_152386675 0.683 ENSMUST00000015124.8
Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr11_-_100822525 0.650 ENSMUST00000107358.2
Stat5b
signal transducer and activator of transcription 5B
chr7_+_30712209 0.553 ENSMUST00000005692.6
ENSMUST00000170371.1
Atp4a

ATPase, H+/K+ exchanging, gastric, alpha polypeptide

chr1_-_152386589 0.542 ENSMUST00000162371.1
Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr11_+_113619318 0.512 ENSMUST00000146390.2
ENSMUST00000106630.1
Sstr2

somatostatin receptor 2

chr7_-_109616548 0.489 ENSMUST00000077909.1
ENSMUST00000084738.3
St5

suppression of tumorigenicity 5

chr11_+_116657106 0.489 ENSMUST00000116318.2
Gm11744
predicted gene 11744
chr6_-_137571007 0.448 ENSMUST00000100841.2
Eps8
epidermal growth factor receptor pathway substrate 8
chr8_+_120668222 0.442 ENSMUST00000034276.6
ENSMUST00000181586.1
Cox4i1

cytochrome c oxidase subunit IV isoform 1

chr3_-_59210881 0.441 ENSMUST00000040622.1
P2ry13
purinergic receptor P2Y, G-protein coupled 13
chr6_+_113531675 0.410 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr7_-_127345314 0.388 ENSMUST00000060783.5
Zfp768
zinc finger protein 768
chr12_-_93929102 0.387 ENSMUST00000180321.1
Gm9726
predicted gene 9726
chr8_+_120668308 0.386 ENSMUST00000181795.1
Cox4i1
cytochrome c oxidase subunit IV isoform 1
chr6_+_41546730 0.367 ENSMUST00000103299.1
Trbc2
T cell receptor beta, constant 2
chr9_-_54661666 0.356 ENSMUST00000128624.1
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr7_+_102267795 0.345 ENSMUST00000033289.4
Stim1
stromal interaction molecule 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.8 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 1.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.3 1.1 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 0.7 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
0.1 0.6 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.6 GO:0036376 sodium ion export from cell(GO:0036376)
0.1 0.5 GO:0030432 peristalsis(GO:0030432)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.4 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.4 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 0.3 GO:0070375 ERK5 cascade(GO:0070375)
0.1 0.3 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.1 0.3 GO:0006842 tricarboxylic acid transport(GO:0006842) succinate transport(GO:0015744) citrate transport(GO:0015746)
0.0 0.3 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.2 GO:0033762 response to glucagon(GO:0033762)
0.0 0.2 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.2 GO:0016557 peroxisome membrane biogenesis(GO:0016557)

Gene overrepresentation in cellular_component category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.6 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.1 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.0 GO:0031983 vesicle lumen(GO:0031983)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.8 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 1.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.8 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.6 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.6 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.2 0.5 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.3 GO:0001847 opsonin receptor activity(GO:0001847)
0.1 0.3 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.3 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)