Motif ID: Nr5a2

Z-value: 0.810


Transcription factors associated with Nr5a2:

Gene SymbolEntrez IDGene Name
Nr5a2 ENSMUSG00000026398.8 Nr5a2



Activity profile for motif Nr5a2.

activity profile for motif Nr5a2


Sorted Z-values histogram for motif Nr5a2

Sorted Z-values for motif Nr5a2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr5a2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_79716588 1.011 ENSMUST00000099513.1
ENSMUST00000020581.2
 Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr8_+_94152607 0.789 ENSMUST00000034211.8
 Mt3
metallothionein 3
chr9_-_77347816 0.762 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
 Mlip



muscular LMNA-interacting protein



chr6_+_90550789 0.741 ENSMUST00000130418.1
ENSMUST00000032175.8
 Aldh1l1

aldehyde dehydrogenase 1 family, member L1

chr9_-_77347787 0.727 ENSMUST00000184848.1
ENSMUST00000184415.1
 Mlip

muscular LMNA-interacting protein

chr10_-_125328957 0.726 ENSMUST00000063318.2
 Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr9_-_77347889 0.702 ENSMUST00000185039.1
 Mlip
muscular LMNA-interacting protein
chr5_-_3473178 0.694 ENSMUST00000168422.1
 Gm17590
predicted gene, 17590
chr11_+_121702591 0.675 ENSMUST00000125580.1
 Metrnl
meteorin, glial cell differentiation regulator-like
chr15_+_25742314 0.667 ENSMUST00000135981.1
 Myo10
myosin X
chr17_-_83631892 0.606 ENSMUST00000051482.1
 Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr1_-_120074023 0.586 ENSMUST00000056089.7
 Tmem37
transmembrane protein 37
chr19_+_6399746 0.563 ENSMUST00000113468.1
 Rasgrp2
RAS, guanyl releasing protein 2
chr13_+_21722057 0.562 ENSMUST00000110476.3
 Hist1h2bm
histone cluster 1, H2bm
chr18_-_15063560 0.550 ENSMUST00000168989.1
 Kctd1
potassium channel tetramerisation domain containing 1
chr6_+_83349446 0.549 ENSMUST00000136501.1
 Bola3
bolA-like 3 (E. coli)
chrX_-_141874870 0.543 ENSMUST00000182079.1
 Gm15294
predicted gene 15294
chr13_+_29014399 0.537 ENSMUST00000146336.1
ENSMUST00000130109.1
 A330102I10Rik

RIKEN cDNA A330102I10 gene

chr5_-_62765618 0.525 ENSMUST00000159470.1
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_+_140170641 0.524 ENSMUST00000044825.4
 Ndufaf5
NADH dehydrogenase (ubiquinone) complex I, assembly factor 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 100 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.2 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 1.3 GO:0009060 aerobic respiration(GO:0009060)
0.0 1.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.2 1.0 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.0 0.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.9 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.3 0.8 GO:0042822 vitamin B6 metabolic process(GO:0042816) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.3 0.8 GO:0097212 lysosomal membrane organization(GO:0097212)
0.3 0.8 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.1 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.8 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.8 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 0.7 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.2 0.7 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.2 0.7 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 0.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.7 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.6 GO:0019249 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.1 0.6 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.6 GO:0010388 cullin deneddylation(GO:0010388)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.3 GO:0016605 PML body(GO:0016605)
0.1 1.6 GO:0045259 proton-transporting ATP synthase complex(GO:0045259)
0.0 1.6 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 1.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 1.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.0 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.6 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.6 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1 0.5 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0070469 respiratory chain(GO:0070469)
0.0 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 76 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.2 GO:0016504 peptidase activator activity(GO:0016504)
0.3 1.1 GO:0004111 creatine kinase activity(GO:0004111)
0.2 1.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 1.0 GO:0005179 hormone activity(GO:0005179)
0.1 0.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3 0.8 GO:0031403 lithium ion binding(GO:0031403)
0.0 0.8 GO:0070888 E-box binding(GO:0070888)
0.2 0.7 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.2 0.7 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.7 GO:0015288 porin activity(GO:0015288)
0.1 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.7 GO:0008430 selenium binding(GO:0008430)
0.0 0.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.1 0.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.6 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.6 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)