Motif ID: Nr6a1

Z-value: 0.621


Transcription factors associated with Nr6a1:

Gene SymbolEntrez IDGene Name
Nr6a1 ENSMUSG00000063972.7 Nr6a1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr6a1mm10_v2_chr2_-_38926217_38926454-0.049.0e-01Click!


Activity profile for motif Nr6a1.

activity profile for motif Nr6a1


Sorted Z-values histogram for motif Nr6a1

Sorted Z-values for motif Nr6a1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr6a1

PNG image of the network

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Top targets:


Showing 1 to 20 of 64 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_82505274 0.945 ENSMUST00000050872.8
ENSMUST00000064770.2
 Nfib

nuclear factor I/B

chr7_-_145283915 0.916 ENSMUST00000058022.4
 Tpcn2
two pore segment channel 2
chr4_-_82505749 0.804 ENSMUST00000107245.2
ENSMUST00000107246.1
 Nfib

nuclear factor I/B

chr17_+_72918298 0.772 ENSMUST00000024857.6
 Lbh
limb-bud and heart
chr7_+_30314810 0.763 ENSMUST00000054594.8
ENSMUST00000177078.1
ENSMUST00000176504.1
ENSMUST00000176304.1
 Syne4



spectrin repeat containing, nuclear envelope family member 4



chr4_-_45530330 0.717 ENSMUST00000061986.5
 Shb
src homology 2 domain-containing transforming protein B
chr9_-_96437434 0.584 ENSMUST00000070500.2
 BC043934
cDNA sequence BC043934
chr5_-_137611429 0.568 ENSMUST00000031731.7
 Pcolce
procollagen C-endopeptidase enhancer protein
chr6_+_42245907 0.562 ENSMUST00000031897.5
 Gstk1
glutathione S-transferase kappa 1
chr5_-_137611372 0.504 ENSMUST00000054564.6
 Pcolce
procollagen C-endopeptidase enhancer protein
chr16_+_17276337 0.461 ENSMUST00000159065.1
ENSMUST00000159494.1
ENSMUST00000159811.1
 Tmem191c


transmembrane protein 191C


chr14_+_12189943 0.436 ENSMUST00000119888.1
 Ptprg
protein tyrosine phosphatase, receptor type, G
chr12_-_115790884 0.322 ENSMUST00000081809.5
 Ighv1-73
immunoglobulin heavy variable 1-73
chr2_+_25054396 0.316 ENSMUST00000102931.4
ENSMUST00000074422.7
ENSMUST00000132172.1
ENSMUST00000114388.1
ENSMUST00000114386.1
 Nsmf




NMDA receptor synaptonuclear signaling and neuronal migration factor




chr5_+_136987019 0.299 ENSMUST00000004968.4
 Plod3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr2_+_172472512 0.286 ENSMUST00000029007.2
 Fam209
family with sequence similarity 209
chr5_-_5694024 0.270 ENSMUST00000115425.2
ENSMUST00000115427.1
ENSMUST00000115424.2
ENSMUST00000015797.4
 Steap2



six transmembrane epithelial antigen of prostate 2



chr4_-_125065603 0.266 ENSMUST00000036383.3
 Dnali1
dynein, axonemal, light intermediate polypeptide 1
chr16_+_17276291 0.260 ENSMUST00000164950.1
ENSMUST00000159242.1
 Tmem191c

transmembrane protein 191C

chr11_-_69822144 0.258 ENSMUST00000045771.6
 Spem1
sperm maturation 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 1.9 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.9 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 0.8 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.8 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 0.4 GO:0097461 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461)
0.0 0.3 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.3 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.3 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.2 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.1 GO:0009838 abscission(GO:0009838)
0.0 0.1 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0 0.1 GO:0046078 dUMP metabolic process(GO:0046078)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.8 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.2 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.1 GO:0090543 Flemming body(GO:0090543)
0.0 0.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)

Gene overrepresentation in molecular_function category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.3 0.9 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.8 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.6 GO:0015035 glutathione peroxidase activity(GO:0004602) protein disulfide oxidoreductase activity(GO:0015035)
0.1 0.4 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.3 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.2 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)