Motif ID: Obox6_Obox5

Z-value: 1.002

Transcription factors associated with Obox6_Obox5:

Gene SymbolEntrez IDGene Name
Obox5 ENSMUSG00000074366.3 Obox5
Obox6 ENSMUSG00000041583.7 Obox6



Activity profile for motif Obox6_Obox5.

activity profile for motif Obox6_Obox5


Sorted Z-values histogram for motif Obox6_Obox5

Sorted Z-values for motif Obox6_Obox5



Network of associatons between targets according to the STRING database.



First level regulatory network of Obox6_Obox5

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_+_1010543 9.167 ENSMUST00000091197.3
 Eif2s3y
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr3_+_95526777 3.827 ENSMUST00000015667.2
ENSMUST00000116304.2
 Ctss

cathepsin S

chr7_-_112159034 2.024 ENSMUST00000033036.5
 Dkk3
dickkopf homolog 3 (Xenopus laevis)
chrX_+_169685191 1.892 ENSMUST00000112104.1
ENSMUST00000112107.1
 Mid1

midline 1

chr5_+_17574268 1.689 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr16_+_59471775 1.682 ENSMUST00000023407.5
ENSMUST00000120667.1
ENSMUST00000120674.1
 Mina


myc induced nuclear antigen


chr8_+_57455898 1.597 ENSMUST00000034023.3
 Scrg1
scrapie responsive gene 1
chr11_-_60046477 1.563 ENSMUST00000000310.7
ENSMUST00000102693.2
ENSMUST00000148512.1
 Pemt


phosphatidylethanolamine N-methyltransferase


chr10_-_33624587 1.543 ENSMUST00000160299.1
ENSMUST00000019920.6
 Clvs2

clavesin 2

chr2_-_77519565 1.520 ENSMUST00000111830.2
 Zfp385b
zinc finger protein 385B
chr19_-_47919269 1.490 ENSMUST00000095998.5
 Itprip
inositol 1,4,5-triphosphate receptor interacting protein
chr10_+_123264076 1.386 ENSMUST00000050756.7
 Fam19a2
family with sequence similarity 19, member A2
chr9_-_77347816 1.138 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
 Mlip



muscular LMNA-interacting protein



chr11_+_3514861 1.134 ENSMUST00000094469.4
 Selm
selenoprotein M
chr9_-_77347787 1.106 ENSMUST00000184848.1
ENSMUST00000184415.1
 Mlip

muscular LMNA-interacting protein

chr7_-_93081027 1.072 ENSMUST00000098303.1
 Gm9934
predicted gene 9934
chr6_+_86195214 1.067 ENSMUST00000032066.9
 Tgfa
transforming growth factor alpha
chr4_+_141368116 1.030 ENSMUST00000006380.4
 Fam131c
family with sequence similarity 131, member C
chr9_-_77347889 0.976 ENSMUST00000185039.1
 Mlip
muscular LMNA-interacting protein
chr4_+_130913120 0.925 ENSMUST00000151698.1
 Laptm5
lysosomal-associated protein transmembrane 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 114 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 9.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.3 4.0 GO:0010447 response to acidic pH(GO:0010447)
0.1 2.9 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.4 2.0 GO:2000065 negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.2 1.7 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 1.7 GO:0043687 post-translational protein modification(GO:0043687)
0.3 1.6 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 1.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.3 1.4 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 1.4 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 1.3 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.3 1.1 GO:0035934 corticosterone secretion(GO:0035934)
0.1 1.1 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 1.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 1.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.1 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.2 1.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.9 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.3 0.8 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.2 0.7 GO:1902358 sulfate transmembrane transport(GO:1902358)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 3.3 GO:0016605 PML body(GO:0016605)
0.0 1.5 GO:0031526 brush border membrane(GO:0031526)
0.3 1.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 1.1 GO:0000786 nucleosome(GO:0000786)
0.1 0.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 0.7 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.7 GO:0002177 manchette(GO:0002177)
0.1 0.6 GO:0033269 internode region of axon(GO:0033269)
0.2 0.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.4 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.4 GO:0045298 tubulin complex(GO:0045298)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.3 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0098536 deuterosome(GO:0098536)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 96 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 4.7 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.2 3.8 GO:0001968 fibronectin binding(GO:0001968)
0.2 1.7 GO:0038191 neuropilin binding(GO:0038191)
0.2 1.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2 1.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.4 GO:0002039 p53 binding(GO:0002039)
0.0 1.3 GO:0005507 copper ion binding(GO:0005507)
0.1 1.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.8 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.8 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.2 0.7 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.7 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.6 GO:0015026 coreceptor activity(GO:0015026)