Motif ID: Olig2_Olig3

Z-value: 0.812

Transcription factors associated with Olig2_Olig3:

Gene SymbolEntrez IDGene Name
Olig2 ENSMUSG00000039830.8 Olig2
Olig3 ENSMUSG00000045591.5 Olig3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Olig2mm10_v2_chr16_+_91225550_91225579-0.678.1e-03Click!
Olig3mm10_v2_chr10_+_19356558_19356565-0.156.2e-01Click!


Activity profile for motif Olig2_Olig3.

activity profile for motif Olig2_Olig3


Sorted Z-values histogram for motif Olig2_Olig3

Sorted Z-values for motif Olig2_Olig3



Network of associatons between targets according to the STRING database.



First level regulatory network of Olig2_Olig3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_44558864 2.571 ENSMUST00000023370.4
 Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr16_-_44558879 2.539 ENSMUST00000114634.1
 Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr10_-_64090241 2.484 ENSMUST00000133588.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr10_-_64090265 2.334 ENSMUST00000105439.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr3_-_120886691 2.307 ENSMUST00000182099.1
ENSMUST00000183168.1
ENSMUST00000183276.1
ENSMUST00000182124.1
 6530403H02Rik



RIKEN cDNA 6530403H02 gene



chr17_+_88626549 1.896 ENSMUST00000163588.1
ENSMUST00000064035.6
 Ston1

stonin 1

chr4_+_86053887 1.829 ENSMUST00000107178.2
ENSMUST00000048885.5
ENSMUST00000141889.1
ENSMUST00000120678.1
 Adamtsl1



ADAMTS-like 1



chr11_-_103938211 1.722 ENSMUST00000133774.2
ENSMUST00000149642.1
 Nsf

N-ethylmaleimide sensitive fusion protein

chr3_+_102734496 1.703 ENSMUST00000029451.5
 Tspan2
tetraspanin 2
chr6_+_5725639 1.681 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
 Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr1_-_186117251 1.671 ENSMUST00000045388.7
 Lyplal1
lysophospholipase-like 1
chr17_+_88626569 1.491 ENSMUST00000150023.1
 Ston1
stonin 1
chr12_+_108410625 1.456 ENSMUST00000109857.1
 Eml1
echinoderm microtubule associated protein like 1
chr8_-_34146974 1.402 ENSMUST00000033910.8
 Leprotl1
leptin receptor overlapping transcript-like 1
chr5_-_24902315 1.384 ENSMUST00000131486.1
 Prkag2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr13_+_16014457 1.383 ENSMUST00000164993.1
 Inhba
inhibin beta-A
chr5_-_66618636 1.351 ENSMUST00000162382.1
ENSMUST00000160870.1
ENSMUST00000087256.5
ENSMUST00000160103.1
ENSMUST00000162349.1
 Apbb2




amyloid beta (A4) precursor protein-binding, family B, member 2




chr8_+_36489191 1.306 ENSMUST00000171777.1
 6430573F11Rik
RIKEN cDNA 6430573F11 gene
chr2_-_80129458 1.300 ENSMUST00000102653.1
 Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr2_+_136892168 1.286 ENSMUST00000099311.2
 Slx4ip
SLX4 interacting protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 116 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 4.8 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.2 4.8 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 2.8 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 2.7 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 2.7 GO:0030048 actin filament-based movement(GO:0030048)
0.1 2.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.6 1.7 GO:0048211 Golgi vesicle docking(GO:0048211)
0.6 1.7 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.3 1.7 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.3 1.7 GO:0032796 uropod organization(GO:0032796)
0.0 1.7 GO:0047496 vesicle transport along microtubule(GO:0047496)
0.3 1.4 GO:0042701 progesterone secretion(GO:0042701)
0.3 1.4 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 1.3 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 1.3 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.1 1.2 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 1.2 GO:0010107 potassium ion import(GO:0010107)
0.0 1.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 1.0 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.0 1.0 GO:0014037 Schwann cell differentiation(GO:0014037)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 4.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.2 2.7 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 2.7 GO:0043209 myelin sheath(GO:0043209)
0.0 2.3 GO:0043198 dendritic shaft(GO:0043198)
0.1 1.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.6 GO:0043034 costamere(GO:0043034)
0.5 1.4 GO:0043512 inhibin A complex(GO:0043512)
0.1 1.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.3 1.2 GO:0031673 H zone(GO:0031673)
0.0 1.2 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.2 GO:0031201 SNARE complex(GO:0031201)
0.1 1.0 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.0 GO:0030315 T-tubule(GO:0030315)
0.1 0.9 GO:0005642 annulate lamellae(GO:0005642)
0.2 0.6 GO:0044299 C-fiber(GO:0044299)
0.0 0.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.5 GO:0033391 chromatoid body(GO:0033391)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 91 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 3.4 GO:0008017 microtubule binding(GO:0008017)
0.1 2.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.3 2.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 1.7 GO:0045503 dynein light chain binding(GO:0045503)
0.2 1.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 1.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.7 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 1.6 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) DNA-methyltransferase activity(GO:0009008) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.2 1.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 1.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 1.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 1.2 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.3 1.0 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.1 0.9 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 0.9 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.9 GO:0070008 serine-type exopeptidase activity(GO:0070008)