Motif ID: Onecut2_Onecut3
Z-value: 1.007
Transcription factors associated with Onecut2_Onecut3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Onecut2 | ENSMUSG00000045991.12 | Onecut2 |
Onecut3 | ENSMUSG00000045518.8 | Onecut3 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Onecut2 | mm10_v2_chr18_+_64340225_64340364 | 0.44 | 1.1e-01 | Click! |
Onecut3 | mm10_v2_chr10_+_80494835_80494873 | -0.28 | 3.4e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 3.4 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
0.7 | 2.1 | GO:0030210 | heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014) |
0.7 | 2.1 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
0.6 | 3.2 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
0.5 | 1.5 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
0.3 | 2.1 | GO:0033600 | negative regulation of mammary gland epithelial cell proliferation(GO:0033600) |
0.3 | 0.9 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
0.2 | 2.3 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
0.2 | 1.0 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
0.2 | 2.0 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
0.2 | 0.6 | GO:0070836 | caveola assembly(GO:0070836) |
0.2 | 1.5 | GO:0097421 | liver regeneration(GO:0097421) |
0.1 | 0.8 | GO:0051987 | positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987) |
0.1 | 0.3 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
0.1 | 0.3 | GO:0006285 | base-excision repair, AP site formation(GO:0006285) |
0.1 | 0.9 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
0.1 | 0.3 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
0.1 | 2.2 | GO:0006828 | manganese ion transport(GO:0006828) |
0.1 | 3.3 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
0.1 | 0.3 | GO:0009812 | flavonoid metabolic process(GO:0009812) flavonoid biosynthetic process(GO:0009813) flavonoid glucuronidation(GO:0052696) |
0.1 | 0.3 | GO:1902071 | regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071) |
0.1 | 0.7 | GO:0048625 | myoblast fate commitment(GO:0048625) |
0.1 | 0.5 | GO:1903847 | regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) |
0.1 | 1.3 | GO:0006825 | copper ion transport(GO:0006825) |
0.1 | 0.6 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
0.1 | 0.3 | GO:0046684 | response to pyrethroid(GO:0046684) |
0.1 | 0.5 | GO:0045199 | maintenance of epithelial cell apical/basal polarity(GO:0045199) |
0.1 | 0.2 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
0.1 | 0.4 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
0.1 | 0.8 | GO:2001275 | positive regulation of glucose import in response to insulin stimulus(GO:2001275) |
0.1 | 0.4 | GO:0050957 | equilibrioception(GO:0050957) |
0.0 | 1.3 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
0.0 | 4.0 | GO:0048663 | neuron fate commitment(GO:0048663) |
0.0 | 0.2 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
0.0 | 0.4 | GO:0032695 | negative regulation of interleukin-12 production(GO:0032695) |
0.0 | 0.5 | GO:0071670 | smooth muscle cell chemotaxis(GO:0071670) |
0.0 | 0.1 | GO:0070543 | response to linoleic acid(GO:0070543) |
0.0 | 0.2 | GO:0032929 | negative regulation of macrophage derived foam cell differentiation(GO:0010745) negative regulation of superoxide anion generation(GO:0032929) |
0.0 | 0.6 | GO:0045792 | negative regulation of cell size(GO:0045792) |
0.0 | 0.3 | GO:0030432 | peristalsis(GO:0030432) |
0.0 | 0.4 | GO:0019985 | translesion synthesis(GO:0019985) |
0.0 | 0.1 | GO:0019478 | D-amino acid catabolic process(GO:0019478) |
0.0 | 0.1 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
0.0 | 0.2 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
0.0 | 0.7 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
0.0 | 0.5 | GO:0032148 | activation of protein kinase B activity(GO:0032148) |
0.0 | 0.1 | GO:0045918 | negative regulation of cytolysis(GO:0045918) |
0.0 | 0.3 | GO:0030574 | collagen catabolic process(GO:0030574) |
0.0 | 0.1 | GO:0016139 | glycoside catabolic process(GO:0016139) |
0.0 | 0.1 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
0.0 | 0.3 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
0.0 | 0.2 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.0 | 0.5 | GO:0030488 | tRNA methylation(GO:0030488) |
0.0 | 0.4 | GO:0007617 | mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705) |
0.0 | 0.4 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
0.0 | 0.4 | GO:0046677 | response to antibiotic(GO:0046677) |
0.0 | 0.1 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
0.0 | 0.4 | GO:1903146 | regulation of mitophagy(GO:1903146) |
0.0 | 0.2 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
0.0 | 0.0 | GO:1903800 | positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
0.0 | 0.1 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.5 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
0.3 | 1.5 | GO:0005955 | calcineurin complex(GO:0005955) |
0.2 | 1.3 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.2 | 2.0 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
0.1 | 1.4 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.1 | 0.9 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
0.1 | 0.4 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
0.1 | 0.7 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
0.1 | 0.8 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
0.0 | 0.2 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.0 | 1.4 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.0 | 2.2 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.0 | 2.5 | GO:0005902 | microvillus(GO:0005902) |
0.0 | 0.2 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.0 | 0.4 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.0 | 0.3 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
0.0 | 0.3 | GO:0005614 | interstitial matrix(GO:0005614) |
0.0 | 0.9 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
0.0 | 2.9 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
0.0 | 0.0 | GO:0014802 | terminal cisterna(GO:0014802) |
0.0 | 0.1 | GO:0045277 | respiratory chain complex IV(GO:0045277) |
0.0 | 0.9 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.0 | 0.3 | GO:0030894 | replisome(GO:0030894) |
0.0 | 4.4 | GO:0005667 | transcription factor complex(GO:0005667) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 2.3 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
0.5 | 3.2 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
0.4 | 3.4 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.3 | 3.1 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
0.3 | 0.9 | GO:0004942 | anaphylatoxin receptor activity(GO:0004942) |
0.3 | 1.3 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
0.3 | 1.5 | GO:0033192 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192) |
0.2 | 2.2 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.2 | 0.7 | GO:0043515 | kinetochore binding(GO:0043515) |
0.2 | 2.1 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
0.2 | 2.1 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
0.1 | 0.3 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
0.1 | 0.3 | GO:0070052 | collagen V binding(GO:0070052) |
0.1 | 1.0 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
0.1 | 1.5 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
0.1 | 1.6 | GO:0045295 | gamma-catenin binding(GO:0045295) |
0.1 | 0.2 | GO:0004605 | phosphatidate cytidylyltransferase activity(GO:0004605) |
0.1 | 0.5 | GO:0015616 | DNA translocase activity(GO:0015616) |
0.1 | 0.2 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) |
0.1 | 0.3 | GO:0052630 | CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630) |
0.1 | 0.2 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.0 | 0.1 | GO:0004560 | alpha-L-fucosidase activity(GO:0004560) |
0.0 | 0.3 | GO:0004983 | neuropeptide Y receptor activity(GO:0004983) |
0.0 | 0.4 | GO:0004622 | lysophospholipase activity(GO:0004622) |
0.0 | 0.1 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
0.0 | 2.0 | GO:0031593 | polyubiquitin binding(GO:0031593) |
0.0 | 0.4 | GO:0016443 | bidentate ribonuclease III activity(GO:0016443) |
0.0 | 0.7 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.0 | 0.5 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
0.0 | 0.3 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
0.0 | 0.7 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
0.0 | 0.5 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.0 | 0.1 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.0 | 0.4 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.0 | 0.3 | GO:0004844 | uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
0.0 | 0.5 | GO:0043422 | protein kinase B binding(GO:0043422) |
0.0 | 0.2 | GO:0016215 | acyl-CoA desaturase activity(GO:0016215) |
0.0 | 0.3 | GO:0031402 | sodium ion binding(GO:0031402) |
0.0 | 0.7 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 0.9 | GO:0005179 | hormone activity(GO:0005179) |
0.0 | 0.2 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
0.0 | 0.1 | GO:0001848 | complement binding(GO:0001848) |
0.0 | 0.2 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.0 | 0.0 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319) |
0.0 | 0.1 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
0.0 | 0.5 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
0.0 | 0.0 | GO:0001888 | glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888) |