Motif ID: Osr2_Osr1

Z-value: 1.340

Transcription factors associated with Osr2_Osr1:

Gene SymbolEntrez IDGene Name
Osr1 ENSMUSG00000048387.7 Osr1
Osr2 ENSMUSG00000022330.4 Osr2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Osr1mm10_v2_chr12_+_9574437_9574448-0.165.9e-01Click!


Activity profile for motif Osr2_Osr1.

activity profile for motif Osr2_Osr1


Sorted Z-values histogram for motif Osr2_Osr1

Sorted Z-values for motif Osr2_Osr1



Network of associatons between targets according to the STRING database.



First level regulatory network of Osr2_Osr1

PNG image of the network

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Top targets:


Showing 1 to 20 of 162 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_144209448 6.589 ENSMUST00000077160.5
 Sox5
SRY-box containing gene 5
chr6_-_144209471 6.543 ENSMUST00000038815.7
 Sox5
SRY-box containing gene 5
chr6_-_144209558 5.793 ENSMUST00000111749.1
ENSMUST00000170367.2
 Sox5

SRY-box containing gene 5

chr1_+_90203980 4.483 ENSMUST00000065587.4
ENSMUST00000159654.1
 Ackr3

atypical chemokine receptor 3

chr4_+_102087543 3.185 ENSMUST00000106911.1
 Pde4b
phosphodiesterase 4B, cAMP specific
chr2_-_80128834 2.781 ENSMUST00000102654.4
ENSMUST00000102655.3
 Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr19_-_41206774 2.749 ENSMUST00000025986.7
ENSMUST00000169941.1
 Tll2

tolloid-like 2

chr2_+_136892168 2.630 ENSMUST00000099311.2
 Slx4ip
SLX4 interacting protein
chr10_-_63927434 2.624 ENSMUST00000079279.3
 Gm10118
predicted gene 10118
chr6_-_59024470 2.534 ENSMUST00000089860.5
 Fam13a
family with sequence similarity 13, member A
chr5_-_112589990 2.442 ENSMUST00000183186.1
ENSMUST00000182949.1
 1700034G24Rik

RIKEN cDNA 1700034G24 gene

chr19_-_14598031 2.341 ENSMUST00000167776.2
 Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr19_-_14597983 2.324 ENSMUST00000052011.7
 Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr6_-_59024340 2.288 ENSMUST00000173193.1
 Fam13a
family with sequence similarity 13, member A
chr9_-_16378231 2.249 ENSMUST00000082170.5
 Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr10_-_109823585 1.685 ENSMUST00000161582.1
 Nav3
neuron navigator 3
chr15_-_43869993 1.629 ENSMUST00000067469.4
 Tmem74
transmembrane protein 74
chr10_+_43901782 1.620 ENSMUST00000054418.5
 Rtn4ip1
reticulon 4 interacting protein 1
chr9_+_49102720 1.572 ENSMUST00000070390.5
ENSMUST00000167095.1
 Tmprss5

transmembrane protease, serine 5 (spinesin)

chr9_+_108508005 1.570 ENSMUST00000006838.8
ENSMUST00000134939.1
 Qars

glutaminyl-tRNA synthetase


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.4 18.9 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 4.7 GO:0016055 Wnt signaling pathway(GO:0016055) cell-cell signaling by wnt(GO:0198738)
0.1 4.5 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.2 3.2 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 2.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.5 2.7 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 2.3 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 2.2 GO:0010842 retina layer formation(GO:0010842)
0.4 2.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 2.0 GO:0043039 tRNA aminoacylation(GO:0043039)
0.2 1.8 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.3 1.3 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.2 1.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.4 1.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 1.1 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) negative regulation of protein localization to plasma membrane(GO:1903077) signal transduction involved in cellular response to ammonium ion(GO:1903831) negative regulation of protein localization to cell periphery(GO:1904376) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 1.1 GO:0042168 heme metabolic process(GO:0042168)
0.1 1.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 1.0 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.0 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.3 0.9 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 18.9 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.1 7.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 3.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.5 2.1 GO:1990032 parallel fiber(GO:1990032)
0.0 1.8 GO:0043034 costamere(GO:0043034)
0.0 1.7 GO:0031225 anchored component of membrane(GO:0031225)
0.2 1.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 1.2 GO:0016363 nuclear matrix(GO:0016363)
0.2 1.0 GO:0008623 CHRAC(GO:0008623)
0.3 0.9 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.9 GO:0071437 invadopodium(GO:0071437)
0.1 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.7 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.6 GO:0072562 blood microparticle(GO:0072562)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.3 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.3 GO:0070449 elongin complex(GO:0070449)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 16.7 GO:0046982 protein heterodimerization activity(GO:0046982)
1.5 4.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
0.1 4.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 3.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.4 2.8 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 2.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.5 GO:0070064 proline-rich region binding(GO:0070064)
0.3 2.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 1.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 1.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.6 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812)
0.4 1.3 GO:0032052 bile acid binding(GO:0032052)
0.2 1.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.4 1.2 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.1 1.1 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 1.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 1.1 GO:0005496 steroid binding(GO:0005496)
0.0 1.0 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.0 GO:0004402 histone acetyltransferase activity(GO:0004402)