Motif ID: Otx1

Z-value: 0.345


Transcription factors associated with Otx1:

Gene SymbolEntrez IDGene Name
Otx1 ENSMUSG00000005917.9 Otx1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Otx1mm10_v2_chr11_-_22001605_22001631-0.451.1e-01Click!


Activity profile for motif Otx1.

activity profile for motif Otx1


Sorted Z-values histogram for motif Otx1

Sorted Z-values for motif Otx1



Network of associatons between targets according to the STRING database.



First level regulatory network of Otx1

PNG image of the network

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Top targets:


Showing 1 to 20 of 77 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_60963192 0.956 ENSMUST00000028347.6
 Rbms1
RNA binding motif, single stranded interacting protein 1
chr13_-_60897439 0.841 ENSMUST00000171347.1
ENSMUST00000021884.8
 Ctla2b

cytotoxic T lymphocyte-associated protein 2 beta

chr15_-_74734313 0.704 ENSMUST00000023260.3
 Lypd2
Ly6/Plaur domain containing 2
chrM_+_11734 0.543 ENSMUST00000082418.1
 mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr1_-_165708088 0.477 ENSMUST00000040357.8
ENSMUST00000097474.3
 Rcsd1

RCSD domain containing 1

chr12_-_46818749 0.431 ENSMUST00000021438.6
 Nova1
neuro-oncological ventral antigen 1
chr9_+_68653761 0.417 ENSMUST00000034766.7
 Rora
RAR-related orphan receptor alpha
chr10_+_123264076 0.408 ENSMUST00000050756.7
 Fam19a2
family with sequence similarity 19, member A2
chr7_-_79848191 0.405 ENSMUST00000107392.1
 Anpep
alanyl (membrane) aminopeptidase
chr12_+_103434211 0.393 ENSMUST00000079294.5
ENSMUST00000076788.5
ENSMUST00000076702.5
ENSMUST00000066701.6
ENSMUST00000085065.5
ENSMUST00000140838.1
 Ifi27





interferon, alpha-inducible protein 27





chr10_+_127642975 0.352 ENSMUST00000092074.5
ENSMUST00000120279.1
 Stat6

signal transducer and activator of transcription 6

chr18_+_57468478 0.334 ENSMUST00000091892.2
 Ctxn3
cortexin 3
chr2_+_175275125 0.331 ENSMUST00000109051.1
 Gm14440
predicted gene 14440
chr7_-_83550258 0.325 ENSMUST00000177929.1
 Gm10610
predicted gene 10610
chr9_+_108479849 0.308 ENSMUST00000065014.4
 Lamb2
laminin, beta 2
chr11_-_116694802 0.303 ENSMUST00000079545.5
 St6galnac2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr5_-_5749317 0.291 ENSMUST00000015796.2
 Steap1
six transmembrane epithelial antigen of the prostate 1
chr15_-_79285502 0.269 ENSMUST00000165408.1
 Baiap2l2
BAI1-associated protein 2-like 2
chr11_+_94936224 0.264 ENSMUST00000001547.7
 Col1a1
collagen, type I, alpha 1
chr5_+_109923400 0.223 ENSMUST00000112544.1
 Gm15446
predicted gene 15446

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 0.5 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.1 0.4 GO:0002295 T-helper cell lineage commitment(GO:0002295) interleukin-4-mediated signaling pathway(GO:0035771)
0.1 0.4 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
0.0 0.4 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.1 0.3 GO:0097461 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461)
0.1 0.3 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.1 0.3 GO:0097503 sialylation(GO:0097503)
0.0 0.3 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764) positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286)
0.0 0.2 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.2 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.1 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.1 GO:0048069 eye pigmentation(GO:0048069)
0.0 0.1 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:0032911 nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911)

Gene overrepresentation in cellular_component category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.4 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.3 GO:0005584 collagen type I trimer(GO:0005584)
0.1 0.3 GO:0043256 laminin complex(GO:0043256)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)

Gene overrepresentation in molecular_function category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.4 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.1 0.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.3 GO:0008932 lytic endotransglycosylase activity(GO:0008932)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.2 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0071862 protein phosphatase type 1 activator activity(GO:0071862)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.0 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)