Motif ID: Pax2

Z-value: 0.772


Transcription factors associated with Pax2:

Gene SymbolEntrez IDGene Name
Pax2 ENSMUSG00000004231.9 Pax2



Activity profile for motif Pax2.

activity profile for motif Pax2


Sorted Z-values histogram for motif Pax2

Sorted Z-values for motif Pax2



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_17463927 1.426 ENSMUST00000115442.1
 Met
met proto-oncogene
chr13_-_92131494 1.345 ENSMUST00000099326.3
ENSMUST00000146492.1
 Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chr13_+_13590402 0.966 ENSMUST00000110559.1
 Lyst
lysosomal trafficking regulator
chr16_-_45158183 0.904 ENSMUST00000114600.1
 Slc35a5
solute carrier family 35, member A5
chr17_-_63863791 0.851 ENSMUST00000050753.3
 A930002H24Rik
RIKEN cDNA A930002H24 gene
chr9_+_64811313 0.787 ENSMUST00000038890.5
 Dennd4a
DENN/MADD domain containing 4A
chr2_+_166805506 0.784 ENSMUST00000099078.3
 Arfgef2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr5_-_124425572 0.770 ENSMUST00000168651.1
 Sbno1
sno, strawberry notch homolog 1 (Drosophila)
chr11_+_35769462 0.765 ENSMUST00000018990.7
 Pank3
pantothenate kinase 3
chr2_+_119594288 0.752 ENSMUST00000147425.1
ENSMUST00000153581.1
 1700020I14Rik

RIKEN cDNA 1700020I14 gene

chr16_+_94370786 0.680 ENSMUST00000147046.1
ENSMUST00000149885.1
ENSMUST00000127667.1
ENSMUST00000119131.1
ENSMUST00000145883.1
 Ttc3




tetratricopeptide repeat domain 3




chr2_+_48949495 0.668 ENSMUST00000112745.1
 Mbd5
methyl-CpG binding domain protein 5
chr16_-_45158453 0.652 ENSMUST00000181750.1
 Slc35a5
solute carrier family 35, member A5
chr16_-_45158566 0.647 ENSMUST00000181177.1
 Slc35a5
solute carrier family 35, member A5
chr16_-_45158624 0.627 ENSMUST00000180636.1
 Slc35a5
solute carrier family 35, member A5
chr10_+_111164794 0.609 ENSMUST00000105275.1
ENSMUST00000095310.1
 Osbpl8

oxysterol binding protein-like 8

chr9_+_70679016 0.602 ENSMUST00000144537.1
 Adam10
a disintegrin and metallopeptidase domain 10
chr2_+_71786923 0.588 ENSMUST00000112101.1
ENSMUST00000028522.3
 Itga6

integrin alpha 6

chr6_-_39725193 0.582 ENSMUST00000101497.3
 Braf
Braf transforming gene
chr14_+_34674122 0.582 ENSMUST00000169910.1
 Wapal
wings apart-like homolog (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 66 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.0 GO:0008643 carbohydrate transport(GO:0008643)
0.2 1.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 1.3 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.4 1.1 GO:1901254 positive regulation of intracellular transport of viral material(GO:1901254)
0.3 1.0 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.3 1.0 GO:0033364 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) mast cell secretory granule organization(GO:0033364)
0.0 1.0 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.2 0.9 GO:0042117 monocyte activation(GO:0042117)
0.0 0.9 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.2 0.8 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 0.8 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.1 0.8 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.0 0.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.8 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.2 0.7 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.7 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.7 GO:0060746 parental behavior(GO:0060746)
0.0 0.7 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.2 0.6 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.1 0.6 GO:0035878 nail development(GO:0035878)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.4 GO:0009925 basal plasma membrane(GO:0009925)
0.4 1.1 GO:0042025 viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.1 1.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 1.0 GO:0090544 BAF-type complex(GO:0090544)
0.1 0.9 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 0.8 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.7 GO:0010369 chromocenter(GO:0010369)
0.1 0.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.6 GO:1990391 DNA repair complex(GO:1990391)
0.1 0.5 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.5 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.5 GO:0031430 M band(GO:0031430)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.4 GO:0031523 Myb complex(GO:0031523)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.6 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.4 1.4 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.0 1.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 1.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 1.2 GO:0015485 cholesterol binding(GO:0015485)
0.1 1.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.1 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.2 0.8 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.8 GO:0032564 dATP binding(GO:0032564)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.6 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.6 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.5 GO:0035615 clathrin heavy chain binding(GO:0032050) clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.5 GO:0097109 neuroligin family protein binding(GO:0097109)