Motif ID: Pax3

Z-value: 0.487


Transcription factors associated with Pax3:

Gene SymbolEntrez IDGene Name
Pax3 ENSMUSG00000004872.9 Pax3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax3mm10_v2_chr1_-_78197112_781971340.723.8e-03Click!


Activity profile for motif Pax3.

activity profile for motif Pax3


Sorted Z-values histogram for motif Pax3

Sorted Z-values for motif Pax3



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_114474312 0.927 ENSMUST00000113371.1
ENSMUST00000040504.5
 Klhl4

kelch-like 4

chr12_+_38780284 0.574 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
 Etv1


ets variant gene 1


chr12_+_38781093 0.563 ENSMUST00000161513.1
 Etv1
ets variant gene 1
chr12_+_38780817 0.496 ENSMUST00000160856.1
 Etv1
ets variant gene 1
chr7_+_30121915 0.474 ENSMUST00000098596.3
ENSMUST00000153792.1
 Zfp382

zinc finger protein 382

chr8_-_71043040 0.431 ENSMUST00000170101.1
 Gm17576
predicted gene, 17576
chr4_+_127077374 0.429 ENSMUST00000046751.6
ENSMUST00000094713.3
 Zmym6

zinc finger, MYM-type 6

chrX_-_103623648 0.418 ENSMUST00000156211.1
 Ftx
Ftx transcript, Xist regulator (non-protein coding)
chrX_-_103623704 0.367 ENSMUST00000130063.1
ENSMUST00000125419.1
 Ftx

Ftx transcript, Xist regulator (non-protein coding)

chr10_-_70592782 0.310 ENSMUST00000162251.1
 Phyhipl
phytanoyl-CoA hydroxylase interacting protein-like
chr10_+_82138253 0.298 ENSMUST00000105314.2
 AU041133
expressed sequence AU041133
chr3_+_36159522 0.290 ENSMUST00000165956.2
 D3Ertd254e
DNA segment, Chr 3, ERATO Doi 254, expressed
chr1_+_87404916 0.267 ENSMUST00000173152.1
ENSMUST00000173663.1
 Gigyf2

GRB10 interacting GYF protein 2

chr3_-_59262825 0.262 ENSMUST00000050360.7
 P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr2_-_136387929 0.251 ENSMUST00000035264.2
ENSMUST00000077200.3
 Pak7

p21 protein (Cdc42/Rac)-activated kinase 7

chr12_+_109540979 0.239 ENSMUST00000129245.1
ENSMUST00000143836.1
ENSMUST00000124106.1
 Meg3


maternally expressed 3


chr4_-_25281801 0.232 ENSMUST00000102994.3
 Ufl1
UFM1 specific ligase 1
chr12_+_52699297 0.231 ENSMUST00000095737.3
 Akap6
A kinase (PRKA) anchor protein 6
chr8_+_71887264 0.203 ENSMUST00000034259.7
 Zfp709
zinc finger protein 709
chr2_+_102659213 0.195 ENSMUST00000111213.1
 Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr13_-_21716143 0.193 ENSMUST00000091756.1
 Hist1h2bl
histone cluster 1, H2bl
chr16_-_32877723 0.180 ENSMUST00000119810.1
 1700021K19Rik
RIKEN cDNA 1700021K19 gene
chr8_+_33428709 0.177 ENSMUST00000059351.7
 5930422O12Rik
RIKEN cDNA 5930422O12 gene
chr18_+_35562158 0.165 ENSMUST00000166793.1
 Matr3
matrin 3
chr16_-_88056176 0.150 ENSMUST00000072256.5
ENSMUST00000023652.8
ENSMUST00000114137.1
 Grik1


glutamate receptor, ionotropic, kainate 1


chr4_-_25281752 0.141 ENSMUST00000038705.7
 Ufl1
UFM1 specific ligase 1
chr16_+_32877775 0.134 ENSMUST00000023489.4
ENSMUST00000171325.1
 Fyttd1

forty-two-three domain containing 1

chr2_+_133552159 0.117 ENSMUST00000028836.6
 Bmp2
bone morphogenetic protein 2
chr1_+_176814660 0.117 ENSMUST00000056773.8
ENSMUST00000027785.8
 Sdccag8

serologically defined colon cancer antigen 8

chrX_+_159840463 0.103 ENSMUST00000112451.1
ENSMUST00000112453.2
 Sh3kbp1

SH3-domain kinase binding protein 1

chr13_+_14630237 0.083 ENSMUST00000178289.1
ENSMUST00000038690.4
 AW209491

expressed sequence AW209491

chr17_+_87107621 0.081 ENSMUST00000041369.6
 Socs5
suppressor of cytokine signaling 5
chr11_-_50292302 0.069 ENSMUST00000059458.4
 Maml1
mastermind like 1 (Drosophila)
chr17_+_21691860 0.053 ENSMUST00000072133.4
 Gm10226
predicted gene 10226
chr9_+_64235201 0.043 ENSMUST00000039011.3
 Uchl4
ubiquitin carboxyl-terminal esterase L4
chr4_+_11486002 0.029 ENSMUST00000108307.2
 1110037F02Rik
RIKEN cDNA 1110037F02 gene
chr11_+_3649759 0.023 ENSMUST00000140242.1
 Morc2a
microrchidia 2A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 0.3 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 0.4 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.2 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 1.6 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0060129 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.0 0.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.0 0.1 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0071638 positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.2 GO:0008340 determination of adult lifespan(GO:0008340)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)