Motif ID: Pax5

Z-value: 1.395


Transcription factors associated with Pax5:

Gene SymbolEntrez IDGene Name
Pax5 ENSMUSG00000014030.9 Pax5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax5mm10_v2_chr4_-_44710408_447104180.263.7e-01Click!


Activity profile for motif Pax5.

activity profile for motif Pax5


Sorted Z-values histogram for motif Pax5

Sorted Z-values for motif Pax5



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax5

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_190170671 1.965 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr18_+_65873478 1.906 ENSMUST00000025395.8
ENSMUST00000173530.1
Grp

gastrin releasing peptide

chr11_-_102897123 1.776 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr1_-_190170178 1.611 ENSMUST00000177288.1
Prox1
prospero-related homeobox 1
chr3_+_118433797 1.564 ENSMUST00000180593.1
ENSMUST00000181926.1
ENSMUST00000181060.1
ENSMUST00000181310.1
Gm26871



predicted gene, 26871



chr16_-_37384915 1.462 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
Stxbp5l



syntaxin binding protein 5-like



chr12_+_16653470 1.428 ENSMUST00000111064.1
Ntsr2
neurotensin receptor 2
chr2_-_77816758 1.408 ENSMUST00000111831.1
Zfp385b
zinc finger protein 385B
chr19_+_23141183 1.385 ENSMUST00000036884.1
Klf9
Kruppel-like factor 9
chr8_-_105637403 1.376 ENSMUST00000182046.1
Gm5914
predicted gene 5914
chr11_-_107716517 1.374 ENSMUST00000021065.5
Cacng1
calcium channel, voltage-dependent, gamma subunit 1
chr10_+_127725392 1.325 ENSMUST00000026466.3
Tac2
tachykinin 2
chr6_+_21215472 1.299 ENSMUST00000081542.5
Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
chr12_-_34528844 1.286 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr11_-_77078404 1.283 ENSMUST00000102494.1
Ccdc55
coiled-coil domain containing 55
chr7_+_51878967 1.239 ENSMUST00000051912.6
Gas2
growth arrest specific 2
chr16_-_37384940 1.212 ENSMUST00000114781.1
ENSMUST00000114780.1
Stxbp5l

syntaxin binding protein 5-like

chr5_-_134747241 1.189 ENSMUST00000015138.9
Eln
elastin
chr3_-_116968827 1.178 ENSMUST00000119557.1
Palmd
palmdelphin
chr11_+_77518566 1.171 ENSMUST00000147386.1
Abhd15
abhydrolase domain containing 15

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 303 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 3.6 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 3.4 GO:0017145 stem cell division(GO:0017145)
0.5 3.1 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.1 2.9 GO:0015701 bicarbonate transport(GO:0015701)
0.0 2.7 GO:0008360 regulation of cell shape(GO:0008360)
0.0 2.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 2.5 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1 2.3 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 1.9 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 1.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.4 1.8 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 1.8 GO:0021510 spinal cord development(GO:0021510)
0.5 1.4 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.2 1.4 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.2 1.4 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1 1.4 GO:0090527 actin filament reorganization(GO:0090527)
0.0 1.4 GO:0048278 vesicle docking(GO:0048278)
0.3 1.3 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.2 1.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 1.3 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 127 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 4.0 GO:0005667 transcription factor complex(GO:0005667)
0.7 2.9 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 2.4 GO:0030027 lamellipodium(GO:0030027)
0.0 2.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.2 GO:0031201 SNARE complex(GO:0031201)
0.5 2.0 GO:0097441 basilar dendrite(GO:0097441)
0.1 1.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.5 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 1.4 GO:0035253 ciliary rootlet(GO:0035253)
0.1 1.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.4 GO:0005925 focal adhesion(GO:0005925)
0.0 1.3 GO:0031526 brush border membrane(GO:0031526)
0.4 1.2 GO:0071953 elastic fiber(GO:0071953)
0.1 1.2 GO:0005605 basal lamina(GO:0005605)
0.0 1.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.2 GO:0016234 inclusion body(GO:0016234)
0.2 1.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 1.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 1.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 182 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 4.0 GO:0005178 integrin binding(GO:0005178)
0.4 3.6 GO:0050693 LBD domain binding(GO:0050693)
0.1 3.6 GO:0017091 AU-rich element binding(GO:0017091)
0.1 2.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 2.1 GO:0070888 E-box binding(GO:0070888)
0.1 2.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 1.9 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 1.8 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 1.8 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.7 GO:0002039 p53 binding(GO:0002039)
0.1 1.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 1.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 1.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.5 GO:0018733 3,4-dihydrocoumarin hydrolase activity(GO:0018733)
0.1 1.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 1.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.4 GO:0035326 enhancer binding(GO:0035326)
0.3 1.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 1.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)