Motif ID: Pax8

Z-value: 0.960


Transcription factors associated with Pax8:

Gene SymbolEntrez IDGene Name
Pax8 ENSMUSG00000026976.9 Pax8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax8mm10_v2_chr2_-_24475097_24475215-0.117.0e-01Click!


Activity profile for motif Pax8.

activity profile for motif Pax8


Sorted Z-values histogram for motif Pax8

Sorted Z-values for motif Pax8



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax8

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 35 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_-_66860458 7.835 ENSMUST00000057942.2
 Mc4r
melanocortin 4 receptor
chr7_-_42578588 4.485 ENSMUST00000179470.1
 Gm21028
predicted gene, 21028
chr4_+_103313806 2.741 ENSMUST00000035780.3
 Oma1
OMA1 homolog, zinc metallopeptidase (S. cerevisiae)
chr1_+_6487231 2.040 ENSMUST00000140079.1
ENSMUST00000131494.1
 St18

suppression of tumorigenicity 18

chr13_-_62607499 1.788 ENSMUST00000091563.4
 6720489N17Rik
RIKEN cDNA 6720489N17 gene
chrX_-_105391770 1.167 ENSMUST00000136406.1
ENSMUST00000150604.1
 5330434G04Rik

RIKEN cDNA 5330434G04 gene

chr13_-_25270076 0.970 ENSMUST00000057866.6
 Nrsn1
neurensin 1
chr11_-_69801716 0.934 ENSMUST00000011285.4
ENSMUST00000102585.1
 Fgf11

fibroblast growth factor 11

chr7_-_42706369 0.932 ENSMUST00000180131.1
 Gm17067
predicted gene 17067
chr16_-_17125106 0.908 ENSMUST00000093336.6
 2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr9_+_109052828 0.811 ENSMUST00000124432.1
 Shisa5
shisa homolog 5 (Xenopus laevis)
chrX_-_105391726 0.800 ENSMUST00000142109.1
 5330434G04Rik
RIKEN cDNA 5330434G04 gene
chr7_+_6961160 0.774 ENSMUST00000054055.6
 Usp29
ubiquitin specific peptidase 29
chr4_+_6191093 0.695 ENSMUST00000029907.5
 Ubxn2b
UBX domain protein 2B
chr1_+_65186727 0.582 ENSMUST00000097707.4
ENSMUST00000081154.7
 Pikfyve

phosphoinositide kinase, FYVE finger containing

chr5_+_100196611 0.505 ENSMUST00000066813.1
 Gm9932
predicted gene 9932
chr17_+_21691860 0.493 ENSMUST00000072133.4
 Gm10226
predicted gene 10226
chr4_+_156215920 0.456 ENSMUST00000105572.1
 2310042D19Rik
RIKEN cDNA 2310042D19 gene
chr13_-_62520451 0.450 ENSMUST00000082203.6
ENSMUST00000101547.4
 Zfp934

zinc finger protein 934

chr7_+_112742025 0.430 ENSMUST00000164363.1
 Tead1
TEA domain family member 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 10.6 GO:0002024 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0 0.8 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 0.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.6 GO:0032288 myelin assembly(GO:0032288)
0.1 0.4 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1 0.4 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.4 GO:0014883 transition between fast and slow fiber(GO:0014883) positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460)
0.0 0.1 GO:0042940 D-amino acid transport(GO:0042940)

Gene overrepresentation in cellular_component category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778) mitotic spindle midzone(GO:1990023)
0.0 0.1 GO:0097433 dense body(GO:0097433)

Gene overrepresentation in molecular_function category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.6 7.8 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 2.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0050699 WW domain binding(GO:0050699)
0.1 0.6 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.4 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)