Motif ID: Pbx2
Z-value: 0.849
Transcription factors associated with Pbx2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Pbx2 | ENSMUSG00000034673.8 | Pbx2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Pbx2 | mm10_v2_chr17_+_34593388_34593417 | 0.71 | 4.1e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 10.4 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
0.3 | 1.0 | GO:0030862 | neuroblast division in subventricular zone(GO:0021849) regulation of polarized epithelial cell differentiation(GO:0030860) positive regulation of polarized epithelial cell differentiation(GO:0030862) |
0.2 | 2.0 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) |
0.2 | 1.0 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
0.1 | 0.8 | GO:1903847 | regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) |
0.1 | 1.0 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
0.1 | 0.8 | GO:0017121 | phospholipid scrambling(GO:0017121) |
0.1 | 0.6 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
0.1 | 0.6 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
0.1 | 0.5 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
0.1 | 0.3 | GO:0042795 | snRNA transcription from RNA polymerase II promoter(GO:0042795) |
0.1 | 1.0 | GO:0061162 | establishment of monopolar cell polarity(GO:0061162) |
0.1 | 0.3 | GO:0018377 | N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377) |
0.1 | 0.2 | GO:0002678 | positive regulation of chronic inflammatory response(GO:0002678) |
0.1 | 1.0 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.0 | 1.1 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
0.0 | 0.7 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.0 | 0.1 | GO:0090611 | ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) |
0.0 | 0.2 | GO:1901096 | regulation of autophagosome maturation(GO:1901096) |
0.0 | 0.7 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
0.0 | 0.5 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
0.0 | 0.2 | GO:0010825 | positive regulation of centrosome duplication(GO:0010825) |
0.0 | 0.1 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
0.0 | 0.5 | GO:0097352 | autophagosome maturation(GO:0097352) |
0.0 | 0.4 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
0.0 | 0.1 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
0.0 | 0.2 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
0.0 | 0.1 | GO:1903898 | positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898) |
0.0 | 0.1 | GO:0006547 | histidine metabolic process(GO:0006547) |
0.0 | 0.2 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
0.0 | 5.7 | GO:0006869 | lipid transport(GO:0006869) |
0.0 | 0.4 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
0.0 | 0.5 | GO:0045070 | positive regulation of viral genome replication(GO:0045070) |
0.0 | 0.3 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
0.0 | 0.2 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
0.0 | 0.8 | GO:0031122 | cytoplasmic microtubule organization(GO:0031122) |
0.0 | 0.2 | GO:0051900 | regulation of mitochondrial depolarization(GO:0051900) |
0.0 | 0.3 | GO:0006301 | postreplication repair(GO:0006301) |
0.0 | 0.1 | GO:0033313 | meiotic cell cycle checkpoint(GO:0033313) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.0 | GO:0031011 | Ino80 complex(GO:0031011) |
0.1 | 1.0 | GO:0043196 | varicosity(GO:0043196) |
0.1 | 0.5 | GO:0030891 | VCB complex(GO:0030891) |
0.1 | 10.3 | GO:0044798 | nuclear transcription factor complex(GO:0044798) |
0.1 | 1.0 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
0.0 | 0.7 | GO:0043204 | perikaryon(GO:0043204) |
0.0 | 0.3 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
0.0 | 0.6 | GO:0031083 | BLOC-1 complex(GO:0031083) |
0.0 | 0.1 | GO:0045298 | tubulin complex(GO:0045298) |
0.0 | 0.4 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.0 | 0.1 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
0.0 | 0.1 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
0.0 | 0.1 | GO:0033269 | internode region of axon(GO:0033269) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.6 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
0.2 | 0.6 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
0.1 | 1.0 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.1 | 1.0 | GO:0045294 | alpha-catenin binding(GO:0045294) |
0.1 | 0.8 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.1 | 1.0 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.1 | 0.2 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
0.1 | 0.8 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
0.0 | 0.9 | GO:0030553 | cGMP binding(GO:0030553) |
0.0 | 1.1 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.0 | 0.1 | GO:0017057 | 6-phosphogluconolactonase activity(GO:0017057) |
0.0 | 0.3 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
0.0 | 4.6 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
0.0 | 0.2 | GO:0003945 | N-acetyllactosamine synthase activity(GO:0003945) |
0.0 | 0.3 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.0 | 0.1 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
0.0 | 0.7 | GO:0017025 | TBP-class protein binding(GO:0017025) |
0.0 | 0.1 | GO:0047389 | glycerophosphocholine phosphodiesterase activity(GO:0047389) |
0.0 | 0.1 | GO:0004477 | methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) |
0.0 | 1.0 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 0.5 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
0.0 | 0.2 | GO:0002151 | G-quadruplex RNA binding(GO:0002151) |
0.0 | 0.6 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.0 | 0.4 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 0.9 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 0.1 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
0.0 | 9.6 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
0.0 | 0.1 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.0 | 0.7 | GO:0030276 | clathrin binding(GO:0030276) |
0.0 | 1.6 | GO:0030165 | PDZ domain binding(GO:0030165) |
0.0 | 0.2 | GO:0017160 | Ral GTPase binding(GO:0017160) |