Motif ID: Pbx2

Z-value: 0.849


Transcription factors associated with Pbx2:

Gene SymbolEntrez IDGene Name
Pbx2 ENSMUSG00000034673.8 Pbx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pbx2mm10_v2_chr17_+_34593388_345934170.714.1e-03Click!


Activity profile for motif Pbx2.

activity profile for motif Pbx2


Sorted Z-values histogram for motif Pbx2

Sorted Z-values for motif Pbx2



Network of associatons between targets according to the STRING database.



First level regulatory network of Pbx2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 132 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_143947061 5.817 ENSMUST00000124233.1
 Sox5
SRY-box containing gene 5
chr11_-_110095937 4.632 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
 Abca8a


ATP-binding cassette, sub-family A (ABC1), member 8a


chr6_-_143947092 4.562 ENSMUST00000144289.1
ENSMUST00000111748.1
 Sox5

SRY-box containing gene 5

chr3_+_121953213 3.117 ENSMUST00000037958.7
ENSMUST00000128366.1
 Arhgap29

Rho GTPase activating protein 29

chr15_-_66812593 2.124 ENSMUST00000100572.3
 Sla
src-like adaptor
chr17_+_21690766 1.046 ENSMUST00000097384.1
 Gm10509
predicted gene 10509
chr11_-_110095974 1.029 ENSMUST00000100287.2
 Abca8a
ATP-binding cassette, sub-family A (ABC1), member 8a
chr3_+_32708546 1.013 ENSMUST00000029214.7
 Actl6a
actin-like 6A
chr13_-_99516537 0.991 ENSMUST00000064762.4
 Map1b
microtubule-associated protein 1B
chr2_+_65620829 0.973 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr6_-_127109517 0.966 ENSMUST00000039913.8
 9630033F20Rik
RIKEN cDNA 9630033F20 gene
chrX_+_140367494 0.952 ENSMUST00000141660.1
 Frmpd3
FERM and PDZ domain containing 3
chr12_-_83921809 0.874 ENSMUST00000135962.1
ENSMUST00000155112.1
ENSMUST00000136848.1
ENSMUST00000126943.1
 Numb



numb gene homolog (Drosophila)



chr17_-_45686899 0.858 ENSMUST00000156254.1
 Tmem63b
transmembrane protein 63b
chr1_+_134560190 0.855 ENSMUST00000112198.1
ENSMUST00000112197.1
 Kdm5b

lysine (K)-specific demethylase 5B

chr8_-_84237042 0.850 ENSMUST00000039480.5
 Zswim4
zinc finger SWIM-type containing 4
chr9_+_92309362 0.823 ENSMUST00000098477.1
ENSMUST00000150594.1
 1700057G04Rik

RIKEN cDNA 1700057G04 gene

chr8_-_8639363 0.757 ENSMUST00000152698.1
 Efnb2
ephrin B2
chr16_-_50330987 0.756 ENSMUST00000114488.1
 Bbx
bobby sox homolog (Drosophila)
chr10_-_119240006 0.744 ENSMUST00000020315.6
 Cand1
cullin associated and neddylation disassociated 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 10.4 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 5.7 GO:0006869 lipid transport(GO:0006869)
0.2 2.0 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 1.1 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.3 1.0 GO:0030862 neuroblast division in subventricular zone(GO:0021849) regulation of polarized epithelial cell differentiation(GO:0030860) positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.2 1.0 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 1.0 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 1.0 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.1 1.0 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.8 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 0.8 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.8 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.7 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 0.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.6 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.5 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.5 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.5 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.5 GO:0045070 positive regulation of viral genome replication(GO:0045070)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.3 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.1 1.0 GO:0031011 Ino80 complex(GO:0031011)
0.1 1.0 GO:0043196 varicosity(GO:0043196)
0.1 1.0 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.7 GO:0043204 perikaryon(GO:0043204)
0.0 0.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.5 GO:0030891 VCB complex(GO:0030891)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 4.6 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.5 1.6 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 1.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.0 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 1.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.9 GO:0030553 cGMP binding(GO:0030553)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.7 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.7 GO:0030276 clathrin binding(GO:0030276)
0.2 0.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.5 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)