Motif ID: Pgr_Nr3c1

Z-value: 0.637

Transcription factors associated with Pgr_Nr3c1:

Gene SymbolEntrez IDGene Name
Nr3c1 ENSMUSG00000024431.8 Nr3c1
Pgr ENSMUSG00000031870.10 Pgr

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr3c1mm10_v2_chr18_-_39489880_39489915-0.497.6e-02Click!


Activity profile for motif Pgr_Nr3c1.

activity profile for motif Pgr_Nr3c1


Sorted Z-values histogram for motif Pgr_Nr3c1

Sorted Z-values for motif Pgr_Nr3c1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pgr_Nr3c1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 119 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_20665250 6.275 ENSMUST00000075312.3
 Ttr
transthyretin
chr10_+_97565436 2.050 ENSMUST00000038160.4
 Lum
lumican
chr4_-_136898803 1.075 ENSMUST00000046285.5
 C1qa
complement component 1, q subcomponent, alpha polypeptide
chr7_-_142576492 0.915 ENSMUST00000140716.1
 H19
H19 fetal liver mRNA
chr14_+_99298652 0.718 ENSMUST00000005279.6
 Klf5
Kruppel-like factor 5
chr13_-_84064772 0.671 ENSMUST00000182477.1
 Gm17750
predicted gene, 17750
chr5_+_24364804 0.655 ENSMUST00000030834.4
ENSMUST00000115090.1
 Nos3

nitric oxide synthase 3, endothelial cell

chr11_-_110168073 0.524 ENSMUST00000044850.3
 Abca9
ATP-binding cassette, sub-family A (ABC1), member 9
chr11_-_3931960 0.520 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
 Tcn2




transcobalamin 2




chr10_-_63421739 0.459 ENSMUST00000054760.4
 Gm7075
predicted gene 7075
chr18_-_15063560 0.405 ENSMUST00000168989.1
 Kctd1
potassium channel tetramerisation domain containing 1
chr3_-_33082004 0.384 ENSMUST00000108225.3
 Pex5l
peroxisomal biogenesis factor 5-like
chr11_-_3931789 0.384 ENSMUST00000109992.1
ENSMUST00000109988.1
 Tcn2

transcobalamin 2

chr4_-_143299498 0.363 ENSMUST00000030317.7
 Pdpn
podoplanin
chr2_-_154613425 0.295 ENSMUST00000181369.1
 4930519P11Rik
RIKEN cDNA 4930519P11 gene
chr3_-_95904683 0.281 ENSMUST00000147962.1
ENSMUST00000036181.8
 Car14

carbonic anhydrase 14

chr10_+_14523062 0.271 ENSMUST00000096020.5
 Gm10335
predicted gene 10335
chr3_-_152193803 0.265 ENSMUST00000050073.6
 Dnajb4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr2_-_180776749 0.262 ENSMUST00000061098.2
 Bhlhe23
basic helix-loop-helix family, member e23
chr4_-_143299463 0.261 ENSMUST00000119654.1
 Pdpn
podoplanin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 6.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.5 2.0 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 1.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.3 0.9 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.9 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.2 0.7 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.1 0.7 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.6 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.4 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.3 GO:0046671 negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.3 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.3 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.3 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.1 0.2 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.2 GO:0086013 membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.0 0.2 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.2 GO:0060353 regulation of cell adhesion molecule production(GO:0060353) positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.1 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.7 GO:0005844 polysome(GO:0005844)
0.1 0.4 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.1 0.4 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.3 GO:0045298 tubulin complex(GO:0045298)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)

Gene overrepresentation in molecular_function category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 6.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 2.0 GO:0005518 collagen binding(GO:0005518)
0.1 0.9 GO:0031419 cobalamin binding(GO:0031419)
0.2 0.7 GO:0004517 nitric-oxide synthase activity(GO:0004517) arginine binding(GO:0034618)
0.1 0.6 GO:0008517 folic acid transporter activity(GO:0008517) water channel activity(GO:0015250)
0.1 0.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.2 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)