Motif ID: Pgr_Nr3c1

Z-value: 0.637

Transcription factors associated with Pgr_Nr3c1:

Gene SymbolEntrez IDGene Name
Nr3c1 ENSMUSG00000024431.8 Nr3c1
Pgr ENSMUSG00000031870.10 Pgr

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr3c1mm10_v2_chr18_-_39489880_39489915-0.497.6e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Pgr_Nr3c1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_20665250 6.275 ENSMUST00000075312.3
Ttr
transthyretin
chr10_+_97565436 2.050 ENSMUST00000038160.4
Lum
lumican
chr4_-_136898803 1.075 ENSMUST00000046285.5
C1qa
complement component 1, q subcomponent, alpha polypeptide
chr7_-_142576492 0.915 ENSMUST00000140716.1
H19
H19 fetal liver mRNA
chr14_+_99298652 0.718 ENSMUST00000005279.6
Klf5
Kruppel-like factor 5
chr13_-_84064772 0.671 ENSMUST00000182477.1
Gm17750
predicted gene, 17750
chr5_+_24364804 0.655 ENSMUST00000030834.4
ENSMUST00000115090.1
Nos3

nitric oxide synthase 3, endothelial cell

chr11_-_110168073 0.524 ENSMUST00000044850.3
Abca9
ATP-binding cassette, sub-family A (ABC1), member 9
chr11_-_3931960 0.520 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
Tcn2




transcobalamin 2




chr10_-_63421739 0.459 ENSMUST00000054760.4
Gm7075
predicted gene 7075
chr18_-_15063560 0.405 ENSMUST00000168989.1
Kctd1
potassium channel tetramerisation domain containing 1
chr3_-_33082004 0.384 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chr11_-_3931789 0.384 ENSMUST00000109992.1
ENSMUST00000109988.1
Tcn2

transcobalamin 2

chr4_-_143299498 0.363 ENSMUST00000030317.7
Pdpn
podoplanin
chr2_-_154613425 0.295 ENSMUST00000181369.1
4930519P11Rik
RIKEN cDNA 4930519P11 gene
chr3_-_95904683 0.281 ENSMUST00000147962.1
ENSMUST00000036181.8
Car14

carbonic anhydrase 14

chr10_+_14523062 0.271 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr3_-_152193803 0.265 ENSMUST00000050073.6
Dnajb4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr2_-_180776749 0.262 ENSMUST00000061098.2
Bhlhe23
basic helix-loop-helix family, member e23
chr4_-_143299463 0.261 ENSMUST00000119654.1
Pdpn
podoplanin
chr17_-_25081138 0.261 ENSMUST00000024984.6
Tmem204
transmembrane protein 204
chr11_+_111066154 0.242 ENSMUST00000042970.2
Kcnj2
potassium inwardly-rectifying channel, subfamily J, member 2
chr9_-_79718631 0.235 ENSMUST00000180083.1
Col12a1
collagen, type XII, alpha 1
chr11_-_83649349 0.233 ENSMUST00000001008.5
Ccl3
chemokine (C-C motif) ligand 3
chr5_-_123140135 0.232 ENSMUST00000160099.1
AI480526
expressed sequence AI480526
chr2_-_122611238 0.219 ENSMUST00000028624.8
Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr18_+_9707639 0.214 ENSMUST00000040069.8
Colec12
collectin sub-family member 12
chr1_+_93235836 0.211 ENSMUST00000062202.7
Sned1
sushi, nidogen and EGF-like domains 1
chr8_+_70042768 0.196 ENSMUST00000011450.6
Sugp1
SURP and G patch domain containing 1
chrX_+_101383726 0.196 ENSMUST00000119190.1
Gjb1
gap junction protein, beta 1
chr3_+_106034661 0.192 ENSMUST00000170669.2
Gm4540
predicted gene 4540
chr5_+_30913398 0.191 ENSMUST00000031055.5
Emilin1
elastin microfibril interfacer 1
chr14_+_75845296 0.179 ENSMUST00000142061.1
Tpt1
tumor protein, translationally-controlled 1
chr7_-_109616548 0.166 ENSMUST00000077909.1
ENSMUST00000084738.3
St5

suppression of tumorigenicity 5

chr14_+_75845093 0.158 ENSMUST00000110894.2
Tpt1
tumor protein, translationally-controlled 1
chr19_+_55894508 0.156 ENSMUST00000142291.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr3_-_146839365 0.131 ENSMUST00000084614.3
Gm10288
predicted gene 10288
chr19_-_32466575 0.129 ENSMUST00000078034.3
Rpl9-ps6
ribosomal protein L9, pseudogene 6
chr7_+_30553263 0.125 ENSMUST00000044048.7
Hspb6
heat shock protein, alpha-crystallin-related, B6
chr17_+_34644805 0.125 ENSMUST00000174796.1
Fkbpl
FK506 binding protein-like
chr4_+_152325831 0.124 ENSMUST00000103191.4
ENSMUST00000139685.1
Rpl22

ribosomal protein L22

chr17_-_46031813 0.119 ENSMUST00000024747.7
Vegfa
vascular endothelial growth factor A
chr9_-_79718518 0.118 ENSMUST00000071750.6
Col12a1
collagen, type XII, alpha 1
chr17_-_68004075 0.106 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr1_-_171240055 0.100 ENSMUST00000131286.1
Ndufs2
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr2_+_39008076 0.098 ENSMUST00000112862.1
ENSMUST00000090993.5
Arpc5l

actin related protein 2/3 complex, subunit 5-like

chr9_-_79718720 0.096 ENSMUST00000121227.1
Col12a1
collagen, type XII, alpha 1
chr13_+_75967704 0.092 ENSMUST00000022081.1
Spata9
spermatogenesis associated 9
chr11_+_62820469 0.092 ENSMUST00000108703.1
Trim16
tripartite motif-containing 16
chr9_+_106453838 0.090 ENSMUST00000024260.6
Pcbp4
poly(rC) binding protein 4
chr4_-_72852622 0.090 ENSMUST00000179234.1
ENSMUST00000078617.4
Aldoart1

aldolase 1 A, retrogene 1

chr10_-_116473418 0.087 ENSMUST00000087965.4
ENSMUST00000164271.1
Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr12_-_24493656 0.084 ENSMUST00000073088.2
Gm16372
predicted pseudogene 16372
chr1_-_139377094 0.082 ENSMUST00000131586.1
ENSMUST00000145244.1
Crb1

crumbs homolog 1 (Drosophila)

chr14_-_16575456 0.081 ENSMUST00000063750.6
Rarb
retinoic acid receptor, beta
chr13_+_29016267 0.078 ENSMUST00000140415.1
A330102I10Rik
RIKEN cDNA A330102I10 gene
chr5_+_30814571 0.072 ENSMUST00000031058.8
Mapre3
microtubule-associated protein, RP/EB family, member 3
chr16_-_10543028 0.068 ENSMUST00000184863.1
ENSMUST00000038281.5
Dexi

dexamethasone-induced transcript

chr19_-_55315980 0.065 ENSMUST00000076891.5
Zdhhc6
zinc finger, DHHC domain containing 6
chr11_-_117826092 0.065 ENSMUST00000026661.3
Tk1
thymidine kinase 1
chr2_+_163994960 0.065 ENSMUST00000018470.3
Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr1_-_144004142 0.065 ENSMUST00000127206.1
Rgs2
regulator of G-protein signaling 2
chr18_+_15832772 0.065 ENSMUST00000079733.5
Gm10036
predicted gene 10036
chr7_-_127421787 0.064 ENSMUST00000126756.1
Zfp688
zinc finger protein 688
chr11_+_88294043 0.064 ENSMUST00000037268.4
1700106J16Rik
RIKEN cDNA 1700106J16 gene
chr3_-_33143025 0.063 ENSMUST00000108226.1
Pex5l
peroxisomal biogenesis factor 5-like
chr12_-_73047179 0.061 ENSMUST00000050029.7
Six1
sine oculis-related homeobox 1
chr7_+_131560363 0.057 ENSMUST00000084502.5
Bub3
budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae)
chr8_-_70042685 0.053 ENSMUST00000168013.2
ENSMUST00000050561.6
Mau2

MAU2 chromatid cohesion factor homolog (C. elegans)

chr16_-_5222257 0.048 ENSMUST00000050160.4
AU021092
expressed sequence AU021092
chr5_+_30814722 0.045 ENSMUST00000114724.1
Mapre3
microtubule-associated protein, RP/EB family, member 3
chr16_+_43363855 0.045 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr17_-_46440099 0.045 ENSMUST00000166852.1
Gm5093
predicted gene 5093
chr15_+_82016420 0.044 ENSMUST00000168581.1
ENSMUST00000170630.1
ENSMUST00000164779.1
Xrcc6


X-ray repair complementing defective repair in Chinese hamster cells 6


chr8_-_70234401 0.044 ENSMUST00000019679.5
Armc6
armadillo repeat containing 6
chr17_+_35049966 0.042 ENSMUST00000007257.9
Clic1
chloride intracellular channel 1
chr4_-_120815703 0.040 ENSMUST00000120779.1
Nfyc
nuclear transcription factor-Y gamma
chr2_-_91255995 0.040 ENSMUST00000180732.1
Gm17281
predicted gene, 17281
chr14_-_69732510 0.039 ENSMUST00000036381.8
Chmp7
charged multivesicular body protein 7
chr1_-_139377041 0.037 ENSMUST00000059825.5
Crb1
crumbs homolog 1 (Drosophila)
chr6_-_33060172 0.036 ENSMUST00000115091.1
ENSMUST00000127666.1
Chchd3

coiled-coil-helix-coiled-coil-helix domain containing 3

chr9_+_91368970 0.036 ENSMUST00000172646.1
Zic4
zinc finger protein of the cerebellum 4
chr8_+_46739745 0.036 ENSMUST00000034041.7
Irf2
interferon regulatory factor 2
chr18_-_62756275 0.032 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr7_+_105640448 0.031 ENSMUST00000058333.3
Timm10b
translocase of inner mitochondrial membrane 10B
chr19_+_55316313 0.030 ENSMUST00000095950.2
Vti1a
vesicle transport through interaction with t-SNAREs 1A
chr14_-_124677089 0.029 ENSMUST00000095529.3
Fgf14
fibroblast growth factor 14
chr5_-_17835857 0.029 ENSMUST00000082367.6
Cd36
CD36 antigen
chr11_+_87664274 0.026 ENSMUST00000092800.5
Rnf43
ring finger protein 43
chr7_-_30194150 0.026 ENSMUST00000126116.1
Capns1
calpain, small subunit 1
chr6_-_33060256 0.025 ENSMUST00000066379.4
Chchd3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr11_-_75178792 0.025 ENSMUST00000071562.2
Ovca2
candidate tumor suppressor in ovarian cancer 2
chr11_+_100622971 0.024 ENSMUST00000142993.1
Nkiras2
NFKB inhibitor interacting Ras-like protein 2
chr14_+_123659971 0.021 ENSMUST00000049681.7
Itgbl1
integrin, beta-like 1
chr4_-_53159885 0.020 ENSMUST00000030010.3
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr7_+_6371364 0.020 ENSMUST00000086323.4
ENSMUST00000108559.2
Zfp78

zinc finger protein 78

chr7_+_144838590 0.018 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr7_-_127345314 0.017 ENSMUST00000060783.5
Zfp768
zinc finger protein 768
chr4_-_129742275 0.017 ENSMUST00000066257.5
Khdrbs1
KH domain containing, RNA binding, signal transduction associated 1
chr8_-_31168699 0.015 ENSMUST00000033983.4
Mak16
MAK16 homolog (S. cerevisiae)
chr13_-_106847267 0.014 ENSMUST00000057427.4
Lrrc70
leucine rich repeat containing 70
chr11_-_48816936 0.014 ENSMUST00000140800.1
Trim41
tripartite motif-containing 41
chr6_-_3494587 0.014 ENSMUST00000049985.8
Hepacam2
HEPACAM family member 2
chr7_-_127824469 0.011 ENSMUST00000106267.3
Stx1b
syntaxin 1B
chr19_-_6084873 0.010 ENSMUST00000160977.1
ENSMUST00000159859.1
Zfpl1

zinc finger like protein 1

chr17_-_6961156 0.009 ENSMUST00000063683.6
Tagap1
T cell activation GTPase activating protein 1
chr10_+_102158858 0.008 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
Mgat4c


mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)


chr7_+_45216671 0.007 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr15_-_89477400 0.007 ENSMUST00000165199.1
Arsa
arylsulfatase A
chr18_+_11633276 0.006 ENSMUST00000115861.2
Rbbp8
retinoblastoma binding protein 8
chr14_-_69707546 0.006 ENSMUST00000118374.1
R3hcc1
R3H domain and coiled-coil containing 1
chr11_-_48817332 0.006 ENSMUST00000047145.7
Trim41
tripartite motif-containing 41
chr6_+_34709442 0.004 ENSMUST00000115021.1
Cald1
caldesmon 1
chr11_+_105126425 0.004 ENSMUST00000021030.7
Mettl2
methyltransferase like 2
chr8_+_123373778 0.004 ENSMUST00000057934.3
ENSMUST00000108840.2
Tcf25

transcription factor 25 (basic helix-loop-helix)

chr8_-_71043040 0.002 ENSMUST00000170101.1
Gm17576
predicted gene, 17576
chr16_-_97851796 0.001 ENSMUST00000121584.1
Prdm15
PR domain containing 15
chr11_+_101425068 0.000 ENSMUST00000040561.5
Rundc1
RUN domain containing 1
chr3_+_121531603 0.000 ENSMUST00000180804.1
A530020G20Rik
RIKEN cDNA A530020G20 gene

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.5 2.0 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.3 0.9 GO:0015889 cobalamin transport(GO:0015889)
0.2 0.7 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.1 0.7 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.3 GO:0046671 negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.3 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1 0.9 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 0.2 GO:0006601 creatine biosynthetic process(GO:0006601)
0.1 0.4 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.6 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 1.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.2 GO:0086013 membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.0 0.1 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.0 0.3 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.3 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0 0.2 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.1 GO:0046104 thymidine metabolic process(GO:0046104)
0.0 0.2 GO:0060353 regulation of cell adhesion molecule production(GO:0060353) positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.0 0.0 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.1 0.4 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.3 GO:0045298 tubulin complex(GO:0045298)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.7 GO:0005844 polysome(GO:0005844)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 0.7 GO:0004517 nitric-oxide synthase activity(GO:0004517) arginine binding(GO:0034618)
0.1 0.9 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.6 GO:0008517 folic acid transporter activity(GO:0008517) water channel activity(GO:0015250)
0.0 0.2 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 2.0 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)