Motif ID: Pitx1

Z-value: 0.718


Transcription factors associated with Pitx1:

Gene SymbolEntrez IDGene Name
Pitx1 ENSMUSG00000021506.7 Pitx1



Activity profile for motif Pitx1.

activity profile for motif Pitx1


Sorted Z-values histogram for motif Pitx1

Sorted Z-values for motif Pitx1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pitx1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_99298652 2.335 ENSMUST00000005279.6
Klf5
Kruppel-like factor 5
chr4_-_64046925 2.102 ENSMUST00000107377.3
Tnc
tenascin C
chrX_+_169879596 1.846 ENSMUST00000112105.1
ENSMUST00000078947.5
Mid1

midline 1

chr1_+_167598450 1.755 ENSMUST00000111386.1
ENSMUST00000111384.1
Rxrg

retinoid X receptor gamma

chr4_+_144892813 1.699 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chrX_+_169685191 1.674 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr3_+_95526777 1.554 ENSMUST00000015667.2
ENSMUST00000116304.2
Ctss

cathepsin S

chr4_+_144893077 1.432 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr10_+_21993890 1.361 ENSMUST00000092673.4
Sgk1
serum/glucocorticoid regulated kinase 1
chr6_+_108213086 1.351 ENSMUST00000032192.6
Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr1_+_167598384 1.315 ENSMUST00000015987.3
Rxrg
retinoid X receptor gamma
chr19_+_8617991 1.283 ENSMUST00000010250.2
Slc22a6
solute carrier family 22 (organic anion transporter), member 6
chr13_-_97747373 1.181 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr15_-_79164477 1.165 ENSMUST00000040019.4
Sox10
SRY-box containing gene 10
chr4_+_144893127 1.131 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr19_-_47919269 1.119 ENSMUST00000095998.5
Itprip
inositol 1,4,5-triphosphate receptor interacting protein
chr8_-_46294592 1.118 ENSMUST00000058636.7
Helt
helt bHLH transcription factor
chr8_+_127063893 1.100 ENSMUST00000162309.1
Pard3
par-3 (partitioning defective 3) homolog (C. elegans)
chr8_+_127064022 1.066 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
Pard3


par-3 (partitioning defective 3) homolog (C. elegans)


chr7_-_4752972 1.021 ENSMUST00000183971.1
ENSMUST00000182173.1
ENSMUST00000182738.1
ENSMUST00000184143.1
ENSMUST00000182111.1
ENSMUST00000182048.1
ENSMUST00000063324.7
Cox6b2






cytochrome c oxidase subunit VIb polypeptide 2






chr12_+_58211772 1.003 ENSMUST00000110671.2
ENSMUST00000044299.2
Sstr1

somatostatin receptor 1

chr3_-_33083016 0.937 ENSMUST00000078226.3
ENSMUST00000108224.1
Pex5l

peroxisomal biogenesis factor 5-like

chr18_+_60925612 0.920 ENSMUST00000102888.3
ENSMUST00000025519.4
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr9_+_50617516 0.718 ENSMUST00000141366.1
Pih1d2
PIH1 domain containing 2
chr14_+_26122609 0.683 ENSMUST00000100810.6
Duxbl2
doubl homeobox B-like 2
chr12_+_81631369 0.678 ENSMUST00000036116.5
Ttc9
tetratricopeptide repeat domain 9
chr13_-_116309639 0.669 ENSMUST00000036060.6
Isl1
ISL1 transcription factor, LIM/homeodomain
chr3_-_8964037 0.664 ENSMUST00000091354.5
ENSMUST00000094381.4
Tpd52

tumor protein D52

chr14_+_64588112 0.662 ENSMUST00000181808.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr7_+_30553263 0.623 ENSMUST00000044048.7
Hspb6
heat shock protein, alpha-crystallin-related, B6
chr1_+_177444653 0.604 ENSMUST00000094276.3
Zbtb18
zinc finger and BTB domain containing 18
chr10_+_80329953 0.602 ENSMUST00000105358.1
ENSMUST00000105357.1
ENSMUST00000105354.1
ENSMUST00000105355.1
Reep6



receptor accessory protein 6



chr19_-_36919606 0.601 ENSMUST00000057337.7
Fgfbp3
fibroblast growth factor binding protein 3
chr14_+_25983005 0.595 ENSMUST00000049793.8
Duxbl1
double homeobox B-like 1
chr5_-_125294107 0.594 ENSMUST00000127148.1
Scarb1
scavenger receptor class B, member 1
chr7_-_15879844 0.581 ENSMUST00000172758.1
ENSMUST00000044434.6
Crx

cone-rod homeobox containing gene

chr16_-_10313940 0.573 ENSMUST00000078357.4
Emp2
epithelial membrane protein 2
chr19_-_32196393 0.569 ENSMUST00000151822.1
Sgms1
sphingomyelin synthase 1
chr3_-_113630068 0.547 ENSMUST00000092154.3
ENSMUST00000106536.1
ENSMUST00000106535.1
Rnpc3


RNA-binding region (RNP1, RRM) containing 3


chr18_+_36365774 0.543 ENSMUST00000144158.1
Cystm1
cysteine-rich transmembrane module containing 1
chr4_-_156255327 0.538 ENSMUST00000179919.1
Samd11
sterile alpha motif domain containing 11
chr2_+_119325784 0.526 ENSMUST00000102517.3
Dll4
delta-like 4 (Drosophila)
chr18_+_60925644 0.526 ENSMUST00000115297.1
Camk2a
calcium/calmodulin-dependent protein kinase II alpha
chrX_+_56779699 0.518 ENSMUST00000114772.2
ENSMUST00000114768.3
ENSMUST00000155882.1
Fhl1


four and a half LIM domains 1


chr18_+_73863672 0.510 ENSMUST00000134847.1
Mro
maestro
chr10_+_128225830 0.510 ENSMUST00000026455.7
Mip
major intrinsic protein of eye lens fiber
chr3_+_136670076 0.500 ENSMUST00000070198.7
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr2_+_38341068 0.496 ENSMUST00000133661.1
Lhx2
LIM homeobox protein 2
chr6_+_121300227 0.495 ENSMUST00000064580.7
Slc6a13
solute carrier family 6 (neurotransmitter transporter, GABA), member 13
chrX_+_56779437 0.487 ENSMUST00000114773.3
Fhl1
four and a half LIM domains 1
chr2_+_14388316 0.484 ENSMUST00000114731.1
ENSMUST00000082290.7
Slc39a12

solute carrier family 39 (zinc transporter), member 12

chr17_+_34969912 0.483 ENSMUST00000173680.1
Gm20481
predicted gene 20481
chr13_-_97747399 0.478 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr6_-_35308110 0.477 ENSMUST00000031868.4
Slc13a4
solute carrier family 13 (sodium/sulfate symporters), member 4
chr10_-_127189981 0.473 ENSMUST00000019611.7
Arhgef25
Rho guanine nucleotide exchange factor (GEF) 25
chr7_+_82175156 0.470 ENSMUST00000180243.1
Sh3gl3
SH3-domain GRB2-like 3
chr4_-_137766474 0.469 ENSMUST00000139951.1
Alpl
alkaline phosphatase, liver/bone/kidney
chr4_+_15881255 0.468 ENSMUST00000029876.1
Calb1
calbindin 1
chr19_-_12765447 0.459 ENSMUST00000112933.1
Cntf
ciliary neurotrophic factor
chr3_-_84270782 0.458 ENSMUST00000054990.4
Trim2
tripartite motif-containing 2
chr14_-_54926784 0.454 ENSMUST00000022813.6
Efs
embryonal Fyn-associated substrate
chr3_-_33082004 0.450 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chr11_+_70459940 0.448 ENSMUST00000147289.1
ENSMUST00000126105.1
Zmynd15

zinc finger, MYND-type containing 15

chr13_+_3361029 0.438 ENSMUST00000179981.1
Gm16505
predicted gene 16505
chr4_-_155010984 0.432 ENSMUST00000105631.2
ENSMUST00000139976.2
ENSMUST00000145662.2
Plch2


phospholipase C, eta 2


chr18_+_36281069 0.429 ENSMUST00000051301.3
Pura
purine rich element binding protein A
chr16_+_8470763 0.423 ENSMUST00000046470.9
ENSMUST00000150790.1
ENSMUST00000142899.1
Mettl22


methyltransferase like 22


chr11_+_116657106 0.419 ENSMUST00000116318.2
Gm11744
predicted gene 11744
chr6_+_17749170 0.401 ENSMUST00000053148.7
ENSMUST00000115417.3
St7

suppression of tumorigenicity 7

chr15_+_18818895 0.393 ENSMUST00000166873.2
Cdh10
cadherin 10
chr3_-_57294880 0.382 ENSMUST00000171384.1
Tm4sf1
transmembrane 4 superfamily member 1
chrX_+_134585644 0.360 ENSMUST00000113211.1
Rpl36a
ribosomal protein L36A
chr5_+_3344194 0.359 ENSMUST00000042410.4
Cdk6
cyclin-dependent kinase 6
chr5_+_137787769 0.353 ENSMUST00000035852.7
Zcwpw1
zinc finger, CW type with PWWP domain 1
chr7_+_16781341 0.340 ENSMUST00000108496.2
Slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chr13_+_63014934 0.338 ENSMUST00000091560.4
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr17_-_58991343 0.323 ENSMUST00000025064.7
2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr1_-_191907527 0.311 ENSMUST00000069573.5
1700034H15Rik
RIKEN cDNA 1700034H15 gene
chr18_-_15718046 0.306 ENSMUST00000053017.6
Chst9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr2_+_120476911 0.304 ENSMUST00000110716.1
ENSMUST00000028748.6
ENSMUST00000090028.5
ENSMUST00000110719.2
Capn3



calpain 3



chr7_-_127725616 0.301 ENSMUST00000076091.2
Ctf2
cardiotrophin 2
chr10_+_19951055 0.293 ENSMUST00000152533.1
Map3k5
mitogen-activated protein kinase kinase kinase 5
chr4_+_109343029 0.292 ENSMUST00000030281.5
Eps15
epidermal growth factor receptor pathway substrate 15
chr1_+_74542881 0.283 ENSMUST00000113749.1
ENSMUST00000067916.6
ENSMUST00000113745.1
ENSMUST00000113747.1
ENSMUST00000113750.1
Plcd4




phospholipase C, delta 4




chr7_-_13034722 0.268 ENSMUST00000005711.4
Chmp2a
charged multivesicular body protein 2A
chr11_+_87578384 0.260 ENSMUST00000107962.1
ENSMUST00000122067.1
Sept4

septin 4

chr9_+_31030621 0.255 ENSMUST00000115222.2
Zbtb44
zinc finger and BTB domain containing 44
chr4_+_84884418 0.254 ENSMUST00000169371.2
Cntln
centlein, centrosomal protein
chr17_-_57059795 0.252 ENSMUST00000040280.7
Slc25a23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr3_+_136670679 0.252 ENSMUST00000056758.8
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr6_+_3993776 0.250 ENSMUST00000031673.5
Gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr10_-_127288999 0.247 ENSMUST00000119078.1
Mbd6
methyl-CpG binding domain protein 6
chr10_+_25408346 0.243 ENSMUST00000092645.6
Epb4.1l2
erythrocyte protein band 4.1-like 2
chr10_-_127288851 0.241 ENSMUST00000156208.1
ENSMUST00000026476.6
Mbd6

methyl-CpG binding domain protein 6

chr4_+_116708687 0.239 ENSMUST00000135499.1
Ccdc163
coiled-coil domain containing 163
chr10_-_22149270 0.238 ENSMUST00000179054.1
ENSMUST00000069372.6
E030030I06Rik

RIKEN cDNA E030030I06 gene

chr10_+_80292453 0.222 ENSMUST00000068408.7
ENSMUST00000062674.6
Rps15

ribosomal protein S15

chr18_+_37447641 0.209 ENSMUST00000052387.3
Pcdhb14
protocadherin beta 14
chr7_-_80403315 0.208 ENSMUST00000147150.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr5_+_8422831 0.208 ENSMUST00000066921.3
Slc25a40
solute carrier family 25, member 40
chr18_+_37320374 0.206 ENSMUST00000078271.2
Pcdhb5
protocadherin beta 5
chrM_+_8600 0.198 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chrX_+_7909542 0.193 ENSMUST00000086274.2
Gm10490
predicted gene 10490
chr13_-_113618549 0.188 ENSMUST00000109241.3
Snx18
sorting nexin 18
chr9_+_58134535 0.186 ENSMUST00000128378.1
ENSMUST00000150820.1
ENSMUST00000167479.1
ENSMUST00000134450.1
Stra6



stimulated by retinoic acid gene 6



chr17_-_24073479 0.184 ENSMUST00000017090.5
Kctd5
potassium channel tetramerisation domain containing 5
chr5_+_64159429 0.183 ENSMUST00000043893.6
Tbc1d1
TBC1 domain family, member 1
chr7_+_5062143 0.181 ENSMUST00000005041.7
U2af2
U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2
chr7_+_13398115 0.181 ENSMUST00000005791.7
Cabp5
calcium binding protein 5
chr6_-_122340200 0.181 ENSMUST00000159384.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr16_+_90831113 0.179 ENSMUST00000037539.7
ENSMUST00000099543.3
Eva1c

eva-1 homolog C (C. elegans)

chr16_-_31081363 0.177 ENSMUST00000055389.7
Xxylt1
xyloside xylosyltransferase 1
chr4_+_129960760 0.176 ENSMUST00000139884.1
1700003M07Rik
RIKEN cDNA 1700003M07 gene
chr2_-_121456693 0.174 ENSMUST00000110613.2
ENSMUST00000056312.3
Serinc4

serine incorporator 4

chr5_+_66968961 0.174 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr1_-_165934900 0.173 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
Pou2f1


POU domain, class 2, transcription factor 1


chr9_-_50617228 0.158 ENSMUST00000147671.1
ENSMUST00000145139.1
ENSMUST00000155435.1
AU019823


expressed sequence AU019823


chr10_-_103029043 0.149 ENSMUST00000167156.2
Alx1
ALX homeobox 1
chr1_-_51915968 0.149 ENSMUST00000046390.7
Myo1b
myosin IB
chr3_+_105973711 0.145 ENSMUST00000000573.2
Ovgp1
oviductal glycoprotein 1
chr7_+_101969796 0.145 ENSMUST00000084852.5
Numa1
nuclear mitotic apparatus protein 1
chr9_+_44101722 0.142 ENSMUST00000161703.1
ENSMUST00000161381.1
ENSMUST00000034654.7
Mfrp


membrane-type frizzled-related protein


chr17_-_23586214 0.141 ENSMUST00000115516.3
Zfp13
zinc finger protein 13
chrX_+_7728439 0.141 ENSMUST00000033489.7
Praf2
PRA1 domain family 2
chr6_-_124840192 0.140 ENSMUST00000024206.5
Gnb3
guanine nucleotide binding protein (G protein), beta 3
chr8_+_85060055 0.140 ENSMUST00000095220.3
Fbxw9
F-box and WD-40 domain protein 9
chr17_+_7925990 0.140 ENSMUST00000036370.7
Tagap
T cell activation Rho GTPase activating protein
chr7_-_98656530 0.129 ENSMUST00000038359.4
2210018M11Rik
RIKEN cDNA 2210018M11 gene
chr11_+_98026695 0.129 ENSMUST00000092425.4
Rpl19
ribosomal protein L19
chr11_-_69398226 0.128 ENSMUST00000050140.5
Tmem88
transmembrane protein 88
chr10_-_9901079 0.127 ENSMUST00000141722.1
Stxbp5
syntaxin binding protein 5 (tomosyn)
chr11_+_4186789 0.125 ENSMUST00000041042.6
ENSMUST00000180088.1
Tbc1d10a

TBC1 domain family, member 10a

chr7_-_134232005 0.123 ENSMUST00000134504.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr5_+_8422908 0.119 ENSMUST00000170496.1
Slc25a40
solute carrier family 25, member 40
chr15_+_102331700 0.113 ENSMUST00000113682.2
ENSMUST00000001331.6
ENSMUST00000171244.1
Myg1


melanocyte proliferating gene 1


chrX_+_82948861 0.109 ENSMUST00000114000.1
Dmd
dystrophin, muscular dystrophy
chr11_+_19924354 0.109 ENSMUST00000093299.6
Spred2
sprouty-related, EVH1 domain containing 2
chr3_+_79884496 0.101 ENSMUST00000118853.1
Fam198b
family with sequence similarity 198, member B
chr2_+_121456963 0.097 ENSMUST00000126764.1
Hypk
huntingtin interacting protein K
chr11_-_22982090 0.092 ENSMUST00000093270.5
ENSMUST00000071068.8
ENSMUST00000159081.1
ENSMUST00000160826.1
Commd1


RP23-242C19.7
COMM domain containing 1


UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 (B3gnt2), transcript variant 2, mRNA
chr9_-_99876147 0.088 ENSMUST00000054819.8
Sox14
SRY-box containing gene 14
chr10_+_90576872 0.083 ENSMUST00000182550.1
ENSMUST00000099364.5
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr12_+_8921598 0.073 ENSMUST00000020909.3
Laptm4a
lysosomal-associated protein transmembrane 4A
chr10_-_117376955 0.072 ENSMUST00000069168.6
ENSMUST00000176686.1
Cpsf6

cleavage and polyadenylation specific factor 6

chr19_-_6077183 0.070 ENSMUST00000025711.5
ENSMUST00000160590.1
Vps51

vacuolar protein sorting 51 homolog (S. cerevisiae)

chr2_+_69670100 0.068 ENSMUST00000100050.3
Klhl41
kelch-like 41
chr11_+_95010277 0.063 ENSMUST00000124735.1
Samd14
sterile alpha motif domain containing 14
chr2_+_102658640 0.056 ENSMUST00000080210.3
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr11_-_106920359 0.053 ENSMUST00000167787.1
ENSMUST00000092517.2
Smurf2

SMAD specific E3 ubiquitin protein ligase 2

chr10_-_14718191 0.052 ENSMUST00000020016.4
Gje1
gap junction protein, epsilon 1
chr4_-_133968611 0.048 ENSMUST00000102552.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr7_+_120917744 0.047 ENSMUST00000033173.7
ENSMUST00000106483.2
Polr3e

polymerase (RNA) III (DNA directed) polypeptide E

chr9_-_50617428 0.046 ENSMUST00000131351.1
ENSMUST00000171462.1
AU019823

expressed sequence AU019823

chr19_+_36083696 0.045 ENSMUST00000025714.7
Rpp30
ribonuclease P/MRP 30 subunit
chr3_+_129199960 0.044 ENSMUST00000173645.2
Pitx2
paired-like homeodomain transcription factor 2
chr13_+_94788873 0.043 ENSMUST00000046644.5
Tbca
tubulin cofactor A
chr9_-_108567336 0.042 ENSMUST00000074208.4
Ndufaf3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr1_-_44218952 0.036 ENSMUST00000054801.3
Mettl21e
methyltransferase like 21E
chr9_-_100486788 0.033 ENSMUST00000098458.3
Il20rb
interleukin 20 receptor beta
chrX_+_134295225 0.031 ENSMUST00000037687.7
Tmem35
transmembrane protein 35
chr14_+_27039001 0.030 ENSMUST00000035336.3
Il17rd
interleukin 17 receptor D
chr13_+_59585259 0.029 ENSMUST00000168367.1
ENSMUST00000022038.7
ENSMUST00000166923.1
Naa35


N(alpha)-acetyltransferase 35, NatC auxiliary subunit


chr8_-_54718664 0.028 ENSMUST00000144711.2
ENSMUST00000093510.2
Wdr17

WD repeat domain 17

chr2_-_64097994 0.024 ENSMUST00000131615.2
Fign
fidgetin
chr17_+_7945653 0.022 ENSMUST00000097423.2
Rsph3a
radial spoke 3A homolog (Chlamydomonas)
chr2_+_121357714 0.021 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
Ckmt1



creatine kinase, mitochondrial 1, ubiquitous



chr6_-_93913678 0.018 ENSMUST00000093769.5
Magi1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr5_+_149184678 0.018 ENSMUST00000139474.1
ENSMUST00000117878.1
Uspl1

ubiquitin specific peptidase like 1

chr5_-_5694559 0.018 ENSMUST00000115426.2
Steap2
six transmembrane epithelial antigen of prostate 2
chr2_+_28506095 0.012 ENSMUST00000074761.4
Gm10134
predicted gene 10134
chr4_-_139833524 0.011 ENSMUST00000030508.7
Pax7
paired box gene 7
chr10_+_94198955 0.006 ENSMUST00000020209.9
ENSMUST00000179990.1
Ndufa12

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12

chr11_+_23256566 0.005 ENSMUST00000136235.1
Xpo1
exportin 1, CRM1 homolog (yeast)
chr6_+_122707489 0.005 ENSMUST00000112581.1
ENSMUST00000112580.1
ENSMUST00000012540.4
Nanog


Nanog homeobox


chr11_+_29718563 0.003 ENSMUST00000060992.5
Rtn4
reticulon 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.4 4.3 GO:0042572 retinol metabolic process(GO:0042572)
0.4 2.2 GO:0003383 apical constriction(GO:0003383)
0.3 2.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.3 0.8 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.2 1.4 GO:0042045 epithelial fluid transport(GO:0042045)
0.2 0.7 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) cardiac cell fate determination(GO:0060913)
0.2 1.4 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.2 0.6 GO:0015920 regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920)
0.2 0.5 GO:0072554 blood vessel lumenization(GO:0072554)
0.2 0.5 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.1 0.4 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1 1.2 GO:0048484 enteric nervous system development(GO:0048484)
0.1 0.5 GO:0048143 astrocyte activation(GO:0048143)
0.1 1.4 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 1.5 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.3 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 1.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.3 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1 1.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.6 GO:0070836 caveola assembly(GO:0070836)
0.1 3.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 0.3 GO:1903722 regulation of centriole elongation(GO:1903722)
0.1 0.6 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.3 GO:0097274 urea homeostasis(GO:0097274)
0.1 0.6 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 3.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 0.4 GO:0032782 bile acid secretion(GO:0032782)
0.1 1.1 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.1 1.0 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.2 GO:0032911 nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.1 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.2 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.0 0.3 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.3 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 0.1 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.0 0.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 1.1 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0 0.3 GO:0015825 L-serine transport(GO:0015825)
0.0 1.0 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.2 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.5 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.0 0.5 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.2 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.5 GO:0007614 short-term memory(GO:0007614)
0.0 0.2 GO:0007602 phototransduction(GO:0007602)
0.0 0.5 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.3 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.3 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.0 GO:0002074 extraocular skeletal muscle development(GO:0002074) pulmonary myocardium development(GO:0003350) subthalamus development(GO:0021539) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.0 0.0 GO:0002765 immune response-inhibiting signal transduction(GO:0002765)
0.0 0.0 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0031088 platelet dense granule membrane(GO:0031088)
0.3 1.4 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.3 2.2 GO:0033269 internode region of axon(GO:0033269)
0.2 0.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 0.8 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 2.1 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.0 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.3 GO:0097227 sperm annulus(GO:0097227)
0.1 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.6 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.6 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.5 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.5 GO:0010369 chromocenter(GO:0010369)
0.0 0.6 GO:0005921 gap junction(GO:0005921)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.6 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.5 1.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.4 2.1 GO:0045545 syndecan binding(GO:0045545)
0.3 1.0 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 3.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.3 1.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 0.6 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 1.4 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 0.5 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.6 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.5 GO:0042731 PH domain binding(GO:0042731)
0.1 1.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.8 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 1.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.8 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 1.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.6 GO:0001968 fibronectin binding(GO:0001968)
0.1 2.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.2 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.5 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.5 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.9 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.3 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 4.0 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.0 0.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)