Motif ID: Pitx1
Z-value: 0.718
Transcription factors associated with Pitx1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Pitx1 | ENSMUSG00000021506.7 | Pitx1 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.8 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
0.4 | 4.3 | GO:0042572 | retinol metabolic process(GO:0042572) |
0.4 | 2.2 | GO:0003383 | apical constriction(GO:0003383) |
0.3 | 2.3 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
0.3 | 0.8 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
0.2 | 1.4 | GO:0042045 | epithelial fluid transport(GO:0042045) |
0.2 | 0.7 | GO:0032650 | regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) cardiac cell fate determination(GO:0060913) |
0.2 | 1.4 | GO:0051461 | protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
0.2 | 0.6 | GO:0015920 | regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920) |
0.2 | 0.5 | GO:0072554 | blood vessel lumenization(GO:0072554) |
0.2 | 0.5 | GO:1902358 | sulfate transmembrane transport(GO:1902358) |
0.1 | 0.4 | GO:0043696 | dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697) |
0.1 | 1.2 | GO:0048484 | enteric nervous system development(GO:0048484) |
0.1 | 0.5 | GO:0048143 | astrocyte activation(GO:0048143) |
0.1 | 1.4 | GO:0038166 | angiotensin-activated signaling pathway(GO:0038166) |
0.1 | 1.5 | GO:0010447 | response to acidic pH(GO:0010447) |
0.1 | 0.3 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
0.1 | 1.3 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
0.1 | 0.3 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
0.1 | 1.4 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
0.1 | 0.6 | GO:0070836 | caveola assembly(GO:0070836) |
0.1 | 3.1 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
0.1 | 0.3 | GO:1903722 | regulation of centriole elongation(GO:1903722) |
0.1 | 0.6 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
0.1 | 0.3 | GO:0097274 | urea homeostasis(GO:0097274) |
0.1 | 0.6 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.1 | 3.2 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
0.1 | 0.4 | GO:0032782 | bile acid secretion(GO:0032782) |
0.1 | 1.1 | GO:0097154 | GABAergic neuron differentiation(GO:0097154) |
0.1 | 1.0 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
0.1 | 0.1 | GO:0008065 | establishment of blood-nerve barrier(GO:0008065) |
0.0 | 0.1 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
0.0 | 0.2 | GO:0032911 | nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911) |
0.0 | 0.1 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
0.0 | 0.2 | GO:0046864 | retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143) |
0.0 | 0.3 | GO:0030382 | sperm mitochondrion organization(GO:0030382) |
0.0 | 0.3 | GO:1904707 | positive regulation of vascular smooth muscle cell proliferation(GO:1904707) |
0.0 | 0.1 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
0.0 | 0.4 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.0 | 1.1 | GO:1902042 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042) |
0.0 | 0.4 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
0.0 | 0.2 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
0.0 | 0.1 | GO:1902071 | regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071) |
0.0 | 0.3 | GO:0015825 | L-serine transport(GO:0015825) |
0.0 | 1.0 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
0.0 | 0.2 | GO:0036089 | cleavage furrow formation(GO:0036089) |
0.0 | 0.5 | GO:2000678 | negative regulation of transcription regulatory region DNA binding(GO:2000678) |
0.0 | 0.5 | GO:0015812 | gamma-aminobutyric acid transport(GO:0015812) |
0.0 | 0.2 | GO:0071699 | olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) |
0.0 | 0.5 | GO:0007614 | short-term memory(GO:0007614) |
0.0 | 0.2 | GO:0007602 | phototransduction(GO:0007602) |
0.0 | 0.5 | GO:0046677 | response to antibiotic(GO:0046677) |
0.0 | 0.1 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
0.0 | 0.1 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
0.0 | 0.3 | GO:0043171 | peptide catabolic process(GO:0043171) |
0.0 | 0.3 | GO:0007340 | acrosome reaction(GO:0007340) |
0.0 | 0.0 | GO:0002074 | extraocular skeletal muscle development(GO:0002074) pulmonary myocardium development(GO:0003350) subthalamus development(GO:0021539) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578) |
0.0 | 0.0 | GO:0002765 | immune response-inhibiting signal transduction(GO:0002765) |
0.0 | 0.0 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.4 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
0.3 | 1.4 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
0.3 | 2.2 | GO:0033269 | internode region of axon(GO:0033269) |
0.2 | 0.5 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
0.2 | 0.8 | GO:0005955 | calcineurin complex(GO:0005955) |
0.1 | 1.2 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.1 | 2.1 | GO:0005614 | interstitial matrix(GO:0005614) |
0.1 | 1.0 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.1 | 0.3 | GO:0097227 | sperm annulus(GO:0097227) |
0.1 | 0.3 | GO:1990604 | IRE1-TRAF2-ASK1 complex(GO:1990604) |
0.1 | 0.6 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
0.0 | 0.6 | GO:0031528 | microvillus membrane(GO:0031528) |
0.0 | 0.5 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
0.0 | 0.4 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.0 | 0.9 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
0.0 | 0.3 | GO:0000815 | ESCRT III complex(GO:0000815) |
0.0 | 0.1 | GO:0000235 | astral microtubule(GO:0000235) |
0.0 | 0.2 | GO:0089701 | U2AF(GO:0089701) |
0.0 | 0.5 | GO:0010369 | chromocenter(GO:0010369) |
0.0 | 0.6 | GO:0005921 | gap junction(GO:0005921) |
0.0 | 0.3 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
0.0 | 0.5 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
0.0 | 0.2 | GO:0001739 | sex chromatin(GO:0001739) |
0.0 | 0.1 | GO:0030312 | external encapsulating structure(GO:0030312) |
0.0 | 0.1 | GO:1990745 | EARP complex(GO:1990745) |
0.0 | 0.2 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
0.0 | 0.6 | GO:0045171 | intercellular bridge(GO:0045171) |
0.0 | 0.1 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 4.2 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.5 | 1.4 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
0.4 | 2.1 | GO:0045545 | syndecan binding(GO:0045545) |
0.3 | 1.0 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
0.3 | 3.1 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
0.3 | 1.4 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
0.2 | 0.6 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
0.2 | 1.4 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.2 | 0.5 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) |
0.1 | 0.6 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.1 | 0.5 | GO:0042731 | PH domain binding(GO:0042731) |
0.1 | 1.1 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.1 | 0.8 | GO:0033192 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192) |
0.1 | 0.5 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
0.1 | 1.3 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
0.1 | 0.8 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
0.1 | 0.4 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
0.1 | 1.4 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
0.1 | 1.6 | GO:0001968 | fibronectin binding(GO:0001968) |
0.1 | 2.4 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.1 | 1.2 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.5 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
0.0 | 0.1 | GO:0004568 | chitinase activity(GO:0004568) |
0.0 | 0.5 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 0.7 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
0.0 | 0.5 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) |
0.0 | 0.3 | GO:0031432 | titin binding(GO:0031432) |
0.0 | 0.5 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.0 | 0.7 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.0 | 1.9 | GO:0098811 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
0.0 | 0.7 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.0 | 0.2 | GO:0048406 | nerve growth factor binding(GO:0048406) |
0.0 | 0.3 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
0.0 | 0.1 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
0.0 | 0.2 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
0.0 | 0.3 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
0.0 | 0.5 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
0.0 | 0.1 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.0 | 0.4 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 4.0 | GO:0043774 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738) |
0.0 | 0.0 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |